PMID- 37575997 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230815 IS - 2296-858X (Print) IS - 2296-858X (Electronic) IS - 2296-858X (Linking) VI - 10 DP - 2023 TI - Advances in multi-modal non-invasive imaging techniques in the diagnosis and treatment of polypoidal choroidal vasculopathy. PG - 1221846 LID - 10.3389/fmed.2023.1221846 [doi] LID - 1221846 AB - Polypoidal choroidal vasculopathy (PCV) is a disease characterized by subretinal pigment epithelium (RPE) orange-red polypoidal lesions and abnormal branching neovascular networks (BNNs). In recent years, various non-invasive imaging technologies have rapidly developed, especially the emergence of optical coherence tomography angiography (OCTA), multi-spectral imaging, and other technologies, which enable the observation of more features of PCV. In addition, these technologies are faster and less invasive compared to indocyanine green angiography (ICGA). Multi-modal imaging, which combined multiple imaging techniques, provides important references for the diagnosis and treatment of PCV with the assistance of regression models, deep learning, and other algorithms. In this study, we reviewed the non-invasive imaging techniques, multi-modal imaging diagnosis, and multi-scene therapeutic applications of PCV, with the aim of providing a reference for non-invasive multi-modal diagnosis and treatment of PCV. CI - Copyright (c) 2023 Wang, Gu and Chen. FAU - Wang, Yuelin AU - Wang Y AD - Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. AD - Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences, Beijing, China. FAU - Gu, Xingwang AU - Gu X AD - Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. AD - Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences, Beijing, China. FAU - Chen, Youxin AU - Chen Y AD - Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. AD - Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences, Beijing, China. LA - eng PT - Journal Article PT - Review DEP - 20230727 PL - Switzerland TA - Front Med (Lausanne) JT - Frontiers in medicine JID - 101648047 PMC - PMC10416106 OTO - NOTNLM OT - diagnosis OT - multimodal OT - non-invasive imaging technology OT - polypoidal choroidal vasculopathy (PCV) OT - treatment COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2023/08/14 06:41 MHDA- 2023/08/14 06:42 PMCR- 2023/07/27 CRDT- 2023/08/14 04:37 PHST- 2023/05/13 00:00 [received] PHST- 2023/07/10 00:00 [accepted] PHST- 2023/08/14 06:42 [medline] PHST- 2023/08/14 06:41 [pubmed] PHST- 2023/08/14 04:37 [entrez] PHST- 2023/07/27 00:00 [pmc-release] AID - 10.3389/fmed.2023.1221846 [doi] PST - epublish SO - Front Med (Lausanne). 2023 Jul 27;10:1221846. doi: 10.3389/fmed.2023.1221846. eCollection 2023.