PMID- 37576100
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231031
IS  - 0971-6203 (Print)
IS  - 1998-3913 (Electronic)
IS  - 0971-6203 (Linking)
VI  - 48
IP  - 2
DP  - 2023 Apr-Jun
TI  - Multivariate Analysis of Effective Dose and Size-Specific Dose Estimates for 
      Thorax and Abdominal Computed Tomography.
PG  - 210-218
LID - 10.4103/jmp.jmp_102_22 [doi]
AB  - The study aimed to compute the effective dose (E) and size-specific dose estimate 
      (SSDE) of routine adult patients undergoing thorax and abdominal computed 
      tomography (CT) imaging and to present their multivariate analysis. All adult 
      thorax and abdominal CT examinations conducted from March 2022 to June 2022 were 
      prospectively included in this study. The Water Equivalent Diameter (D(w)) and 
      SSDE of all the examinations were computed from CT dose index volume (CTDI(vol)) 
      and Dose length product (DLP) displayed on the dose report in the CT console. The 
      multivariate statistical analysis was performed to investigate the correlation of 
      SSDE and E on CTDI(vol), D(w) area of the region of interest (ROI) (Area(ROI)), 
      body mass index (BMI), conversion factor (f(size)) and hounsfield (HU(mean)) 
      number in the ROI at 95% level of significance (P < 0.05). The linear regression 
      analysis was performed to investigate the dependence of SSDE and E on other 
      parameters for both abdominal and thorax patients. A total number of 135 (Abdomen 
      = 61 and Thorax = 74) measurements were performed. The mean value of effective 
      dose for abdomen and thorax patients was found to be 7.17 +/- 3.94 and 4.89 +/- 2.16 
      mSv, respectively. The SSDE was observed to be 13.24 +/- 3.61 and 13.04 +/- 3.61 mGy 
      for thorax and abdomen respectively. The multivariate analysis suggests that SSDE 
      for abdominal CT is found significantly dependent on CTDI(vol), D(w) and f(size) 
      with P < 0.05 and E is found to be significantly dependent on DLP, Area(ROI), 
      D(w) and f(size) at 95% level of confidence for abdominal CT imaging. SSDE for 
      thorax CT was found significantly dependent on BMI, CTDI(vol), HU(mean), D(w) and 
      f(size) at 95% level of confidence. Furthermore, E was observed dependent on DLP 
      at P < 0.05. The linear regression analysis also shows that E is strongly 
      correlated with DLP (r = 1.0) for both thorax and abdominal CT, further the SSDE 
      was observed strongly correlated with CTDI(vol) with r = 0.79 and r = 0.86 for 
      abdomen and thorax CT respectively. A strong correlation was observed between BMI 
      and for D(w) abdominal CT imaging (r = 0.68). The mean value of SSDE for thorax 
      is slightly greater than abdomen. The average value of effective dose for abdomen 
      and thorax measurements was found to be 7.17 +/- 3.94 and 4.89 +/- 2.16 mSv and , 
      correspondingly. SSDE for both abdomen and thorax CT is significantly dependent 
      on CTDI(vol), D(w) and f(size) at 95% level of confidence. The strong correlation 
      was also observed E on DLP and SSDE on CTDI(vol) for both Abdomen and Thorax CT. 
      The strong dependence of D(w) on BMI (r = 0.68) is due to the excessive fat 
      concentration around the stomach and abdomen.
CI  - Copyright: (c) 2023 Journal of Medical Physics.
FAU - Shah, Mudasir Ashraf
AU  - Shah MA
AD  - Department of Radiodiagnosis, Faculty of Medicine, Jawaharlal Nehru Medical 
      College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
FAU - Ahmad, Mehtab
AU  - Ahmad M
AD  - Department of Radiodiagnosis, Faculty of Medicine, Jawaharlal Nehru Medical 
      College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
FAU - Khalid, Saifullah
AU  - Khalid S
AD  - Department of Radiodiagnosis, Faculty of Medicine, Jawaharlal Nehru Medical 
      College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
FAU - Qaseem, Syed M Danish
AU  - Qaseem SMD
AD  - Department of Radiodiagnosis, Faculty of Medicine, Jawaharlal Nehru Medical 
      College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
FAU - Siddiqui, Shaista
AU  - Siddiqui S
AD  - Department of Radiodiagnosis, Faculty of Medicine, Jawaharlal Nehru Medical 
      College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
FAU - Talib, Sayema
AU  - Talib S
AD  - Department of Radiodiagnosis, Faculty of Medicine, Jawaharlal Nehru Medical 
      College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
FAU - Rather, Sajad Ahmed
AU  - Rather SA
AD  - Department of Radiological Physics and Bio-Engineering, Sher-i-Kashmir Institute 
      of Medical Sciences, Srinagar, India.
FAU - Firdous, Arfat
AU  - Firdous A
AD  - Department of Physics, Government Degree College, Sumbal, Jammu and Kashmir, 
      India.
LA  - eng
PT  - Journal Article
DEP - 20230629
PL  - India
TA  - J Med Phys
JT  - Journal of medical physics
JID - 9441104
PMC - PMC10419744
OTO - NOTNLM
OT  - Dose length product
OT  - effective dose
OT  - size-specific dose estimate
OT  - water-equivalent diameter
COIS- There are no conflicts of interest.
EDAT- 2023/08/14 06:41
MHDA- 2023/08/14 06:42
PMCR- 2023/04/01
CRDT- 2023/08/14 04:38
PHST- 2022/11/16 00:00 [received]
PHST- 2023/05/10 00:00 [revised]
PHST- 2023/05/10 00:00 [accepted]
PHST- 2023/08/14 06:42 [medline]
PHST- 2023/08/14 06:41 [pubmed]
PHST- 2023/08/14 04:38 [entrez]
PHST- 2023/04/01 00:00 [pmc-release]
AID - JMP-48-210 [pii]
AID - 10.4103/jmp.jmp_102_22 [doi]
PST - ppublish
SO  - J Med Phys. 2023 Apr-Jun;48(2):210-218. doi: 10.4103/jmp.jmp_102_22. Epub 2023 
      Jun 29.