PMID- 37579665
OWN - NLM
STAT- MEDLINE
DCOM- 20230920
LR  - 20230920
IS  - 1873-3557 (Electronic)
IS  - 1386-1425 (Linking)
VI  - 303
DP  - 2023 Dec 15
TI  - Bipolar hemicyanine cationic probe for simultaneous sensing of ATP and GTP.
PG  - 123249
LID - S1386-1425(23)00934-4 [pii]
LID - 10.1016/j.saa.2023.123249 [doi]
AB  - Adenosine 5'-triphosphate (ATP) and guanosine 5'-triphosphate (GTP) are the most 
      essential energy source in enormous biological processes. Various probes for ATP 
      or GTP sensing, have been widely established, but the probe that could 
      simultaneously monitor ATP and GTP is still rarely reported. Herein, we report a 
      bipolar hemicyanine cationic probe for simultaneous sensing of ATP and GTP via a 
      one-step monitoring process. This probe exhibited strong affinity to ATP and GTP 
      through intramolecular electrostatic and pi-pi stacking interactions, which the 
      binding constant on each step were determined as 6.15 x 10(7) M(-1) and 
      1.57 x 10(6) M(-1) for ATP, 3.19 x 10(7) M(-1) and 3.81 x 10(6) M(-1) for GTP. 
      The sensitivity and specificity of this probe toward ATP or GTP over other twelve 
      biological analogues (adenosine 5'-diphosphate (ADP), adenosine 5'-monophosphate 
      (AMP), guanosine 5'-diphosphate (GDP), guanosine 5'-monophosphate (GMP), Etc.) 
      have also been successfully demonstrated. Furthermore, due to the rapid response 
      rate (within 10 s), we also proved that this probe could be employed as a monitor 
      tool during the ATP or GTP-related enzymatic reaction process.
CI  - Copyright (c) 2023 Elsevier B.V. All rights reserved.
FAU - Niu, Mengxing
AU  - Niu M
AD  - School of Applied Engineering, Henan University of Science and Technology, 
      Sanmenxia 472000, PR China.
FAU - Liang, Xiaofei
AU  - Liang X
AD  - School of Music, Henan University, Kaifeng 475001, PR China.
FAU - Zhao, Haotian
AU  - Zhao H
AD  - Department of Physical Education, Jiangnan University, Wuxi 214122, PR China.
FAU - Li, Huixin
AU  - Li H
AD  - School of Sport Science, Beijing Sport University, Beijing 100084, PR China.
FAU - Fu, Xuancheng
AU  - Fu X
AD  - Department of Chemistry, Syracuse University, Syracuse 13244, United States. 
      Electronic address: fuxuancheng@iccas.ac.cn.
FAU - Liu, Chang
AU  - Liu C
AD  - School of Sport Science, Beijing Sport University, Beijing 100084, PR China. 
      Electronic address: c.liu@bsu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20230809
PL  - England
TA  - Spectrochim Acta A Mol Biomol Spectrosc
JT  - Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
JID - 9602533
RN  - 86-01-1 (Guanosine Triphosphate)
RN  - 0 (tetramethylene hemicyanine)
RN  - NU43IAG5BC (triphosphoric acid)
RN  - 8L70Q75FXE (Adenosine Triphosphate)
RN  - 146-91-8 (Guanosine Diphosphate)
RN  - K72T3FS567 (Adenosine)
SB  - IM
MH  - Guanosine Triphosphate/metabolism
MH  - *Adenosine Triphosphate/metabolism
MH  - Guanosine Diphosphate/metabolism
MH  - *Adenosine
OTO - NOTNLM
OT  - ATP
OT  - Bipolar hemicyanine cationic probe
OT  - GTP
OT  - Simultaneous sensing
OT  - Ultra-rapid monitoring
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/08/15 00:42
MHDA- 2023/09/20 06:42
CRDT- 2023/08/14 18:07
PHST- 2023/04/11 00:00 [received]
PHST- 2023/07/19 00:00 [revised]
PHST- 2023/08/08 00:00 [accepted]
PHST- 2023/09/20 06:42 [medline]
PHST- 2023/08/15 00:42 [pubmed]
PHST- 2023/08/14 18:07 [entrez]
AID - S1386-1425(23)00934-4 [pii]
AID - 10.1016/j.saa.2023.123249 [doi]
PST - ppublish
SO  - Spectrochim Acta A Mol Biomol Spectrosc. 2023 Dec 15;303:123249. doi: 
      10.1016/j.saa.2023.123249. Epub 2023 Aug 9.