PMID- 37580149 OWN - NLM STAT- MEDLINE DCOM- 20230816 LR - 20231029 IS - 1526-632X (Electronic) IS - 0028-3878 (Print) IS - 0028-3878 (Linking) VI - 101 IP - 7 Suppl 1 DP - 2023 Aug 15 TI - Advancing Health Equity in Neurologic Disorders and Stroke: Stakeholder Insights Into Health Disparities, Research Gaps, and Potential Interventions. PG - S92-S103 LID - 10.1212/WNL.0000000000207570 [doi] AB - OBJECTIVES: The purpose of this study was to analyze the National Institute of Neurological Disorders and Stroke (NINDS) Request for Information (RFI) input from the public-including health care providers, researchers, patients, patient advocates, caregivers, advocacy organizations, professional societies, and private and academic stakeholders with an interest in health disparities (HDs) in neurologic disease. RFI questions were structured to solicit input on what stakeholders believe are neurologic disease HD research priorities, drivers of health inequity, and potential interventions. Furthermore, these stakeholder insights were examined within the context of contemporary scientific literature and research frameworks on health equity and health disparities. BACKGROUND: The NINDS published a RFI from March 31 to July 15, 2020. The RFI analysis presented here is part of a larger strategic planning process aimed to guide future NINDS efforts in neurologic disorder health equity (HE) research and training. The public commented on facilitators of HDs, populations that experience HDs (HDPs), potential interventions, and research opportunities related to HDs in neurologic disease and/or care in the United States across the lifespan. Responses were analyzed using qualitative methodology. Frequently suggested interventions were thematically clustered using the interpretive phenomenological analysis methodology and are presented in this article to provide a stakeholder-identified roadmap for advancing HE. RESULTS: Respondents identified socioecological factors as driving HDs in 89% of determinants reported. Stakeholder-reported HD determinants and subsequent interventions could be classified into the following conceptual categories: HDP neurospecialty care access, innovative HDP engagement and research inclusion strategies, and development of a well-trained clinician-scientist HD workforce. Clustering of the feedback from patient and patient-adjacent respondents (i.e., caretakers and patient advocates) highlighted the prevalence of patient-provider interpersonal factors and limited resources driving access-to-care barriers among their sentiments. DISCUSSION: Respondent sentiments suggest prioritization of social determinants of health (SDOH) research, shifting away from the common target of biological and behavioral themes addressed in the existing body of HE research provided by the stakeholder. Overall, respondents suggest focusing research prioritization on access to care, engagement across the HE research and care landscape, and HE workforce development. CI - Copyright (c) 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology. FAU - Littlejohn, Erica L AU - Littlejohn EL AUID- ORCID: 0000-0003-3255-8546 AD - From the Office of Global Health and Health Disparities (E.L.L., N.E.B., S.C., C.A.S., R.T.B.), Division of Clinical Research, Division of Extramural Research, and Neuroimmunology Clinic (J.A.A.), Division of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD. erica.littlejohn@nih.gov. FAU - Booker, Naomi E AU - Booker NE AD - From the Office of Global Health and Health Disparities (E.L.L., N.E.B., S.C., C.A.S., R.T.B.), Division of Clinical Research, Division of Extramural Research, and Neuroimmunology Clinic (J.A.A.), Division of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD. FAU - Chambers, Stacey AU - Chambers S AD - From the Office of Global Health and Health Disparities (E.L.L., N.E.B., S.C., C.A.S., R.T.B.), Division of Clinical Research, Division of Extramural Research, and Neuroimmunology Clinic (J.A.A.), Division of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD. FAU - Akinsanya, Jemima A AU - Akinsanya JA AD - From the Office of Global Health and Health Disparities (E.L.L., N.E.B., S.C., C.A.S., R.T.B.), Division of Clinical Research, Division of Extramural Research, and Neuroimmunology Clinic (J.A.A.), Division of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD. FAU - Sankar, Cheryse A AU - Sankar CA AD - From the Office of Global Health and Health Disparities (E.L.L., N.E.B., S.C., C.A.S., R.T.B.), Division of Clinical Research, Division of Extramural Research, and Neuroimmunology Clinic (J.A.A.), Division of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD. FAU - Benson, Richard T AU - Benson RT AUID- ORCID: 0000-0002-0551-7717 AD - From the Office of Global Health and Health Disparities (E.L.L., N.E.B., S.C., C.A.S., R.T.B.), Division of Clinical Research, Division of Extramural Research, and Neuroimmunology Clinic (J.A.A.), Division of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD. LA - eng PT - Journal Article PL - United States TA - Neurology JT - Neurology JID - 0401060 SB - IM MH - Humans MH - United States MH - Evidence Gaps MH - *Health Equity MH - *Nervous System Diseases/epidemiology/therapy MH - *Stroke/epidemiology/therapy MH - Caregivers PMC - PMC10605949 COIS- The authors report no relevant disclosures. Go to Neurology.org/N for full disclosures. EDAT- 2023/08/15 00:42 MHDA- 2023/08/16 06:43 PMCR- 2024/08/15 CRDT- 2023/08/14 21:23 PHST- 2022/09/09 00:00 [received] PHST- 2023/05/09 00:00 [accepted] PHST- 2024/08/15 00:00 [pmc-release] PHST- 2023/08/16 06:43 [medline] PHST- 2023/08/15 00:42 [pubmed] PHST- 2023/08/14 21:23 [entrez] AID - 101/7_Supplement_1/S92 [pii] AID - WNL-2023-000388 [pii] AID - 10.1212/WNL.0000000000207570 [doi] PST - ppublish SO - Neurology. 2023 Aug 15;101(7 Suppl 1):S92-S103. doi: 10.1212/WNL.0000000000207570.