PMID- 37581743
OWN - NLM
STAT- MEDLINE
DCOM- 20230816
LR  - 20230905
IS  - 1436-5073 (Electronic)
IS  - 0026-3672 (Linking)
VI  - 190
IP  - 9
DP  - 2023 Aug 15
TI  - Vortex-assisted dispersive liquid-liquid microextraction based on the hydrophobic 
      deep eutectic solvent-based ferrofluid for extraction and detection of 
      myclobutanil.
PG  - 352
LID - 10.1007/s00604-023-05884-y [doi]
AB  - A vortex-assisted dispersive liquid-liquid microextraction (VA-DLLME) procedure 
      using hydrophobic deep eutectic solvent-based ferrofluid (HDES-FF) as an 
      extractant was established. The developed sample preparation method coupled with 
      high-performance liquid chromatography-diode array detector (HPLC-DAD) was 
      applied to the pretreatment and determination of myclobutanil (MYC) in fruit 
      juice. Hydrophobic deep eutectic solvent, synthesized by n-decanoic acid and 
      DL-menthol, was as a carrier and combined with magnetic nanoparticles 
      (Fe(3)O(4)@OA) to form HDES-FF as an extractant with high extraction capacity. 
      The synthesized materials were characterized by Fourier transform infrared 
      (FT-IR) spectroscopy, X-ray diffraction (XRD), and vibrating sample magnetometer 
      (VSM). Parameters affecting extraction efficiency were optimized using 
      single-factor experiments and Box-Behnken design via response surface methodology 
      (BBD-RSM). Parallel tests were performed three times under the optimal conditions 
      predicted by the model, yielding an actual mean recovery of 94.77% with RSD of 
      2.7% (n = 3) and an enrichment factor of 41.8 +/- 0.98 (mean value +/- SD, n = 3). 
      Under the optimal conditions, the linear range was 1.0-100.0 microg.mL(-1); the limit 
      of detection (LOD) and limit of quantification (LOQ) were 0.25 and 
      0.80 microg.mL(-1), respectively. The average spiked recoveries in the samples ranged 
      from 98.2 to 100.5% with intra-day relative standard deviations (RSDs) of 
      1.2-3.5% (n = 3) and inter-day RSDs of 1.1-3.8% (n = 3). Finally, the method was 
      successfully applied to the determination of MYC antimicrobial agent in different 
      fruit juice samples. The proposed HDES-FF-VA-DLLME/HPLC-DAD method was verified 
      to widely apply to the extraction of triazole fungicides.
CI  - (c) 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, 
      part of Springer Nature.
FAU - Na, Yue
AU  - Na Y
AD  - School of Pharmacy, Shenyang Pharmaceutical University, Shenhe District, 103 
      Wenhua Road, Shenyang, Liaoning, 110016, People's Republic of China.
FAU - Gao, Xun
AU  - Gao X
AD  - Co-Innovation Center of Jiangsu Marine Bio-Industry Technology, Jiangsu Ocean 
      University, Lianyungang, 222001, People's Republic of China.
FAU - Hong, Jiawei
AU  - Hong J
AD  - School of Pharmacy, Shenyang Pharmaceutical University, Shenhe District, 103 
      Wenhua Road, Shenyang, Liaoning, 110016, People's Republic of China.
FAU - Zhou, Xunyong
AU  - Zhou X
AD  - Guangdong Province, HC Enzyme Biotech Co., Ltd, Shenzhen, 518001, People's 
      Republic of China.
FAU - Liang, Ning
AU  - Liang N
AD  - School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, 
      Liaoning Province, Shenyang, 110016, People's Republic of China. 
      liangning@syphu.edu.cn.
FAU - Zhao, Longshan
AU  - Zhao L
AD  - School of Pharmacy, Shenyang Pharmaceutical University, Shenhe District, 103 
      Wenhua Road, Shenyang, Liaoning, 110016, People's Republic of China. 
      longshanzhao@163.com.
LA  - eng
GR  - YQ202206/Youqing lift Program of Shenyang Pharmaceutical University/
GR  - ZQN2016011/Middle-aged Backbone Personnel Training Program of Shenyang 
      Pharmaceutical University/
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230815
PL  - Austria
TA  - Mikrochim Acta
JT  - Mikrochimica acta
JID - 7808782
RN  - 0 (Solvents)
RN  - B6T1JTM6KZ (systhane)
RN  - 0 (Deep Eutectic Solvents)
RN  - 0 (Triazoles)
SB  - IM
MH  - Solvents/chemistry
MH  - *Deep Eutectic Solvents
MH  - *Liquid Phase Microextraction/methods
MH  - Spectroscopy, Fourier Transform Infrared
MH  - Triazoles
OTO - NOTNLM
OT  - Box-Behnken design
OT  - Fruit juice
OT  - High-performance liquid chromatography-diode array detector
OT  - Magnetic nanoparticles
OT  - Triazole fungicide
EDAT- 2023/08/15 12:43
MHDA- 2023/08/16 06:43
CRDT- 2023/08/15 11:08
PHST- 2023/03/27 00:00 [received]
PHST- 2023/06/26 00:00 [accepted]
PHST- 2023/08/16 06:43 [medline]
PHST- 2023/08/15 12:43 [pubmed]
PHST- 2023/08/15 11:08 [entrez]
AID - 10.1007/s00604-023-05884-y [pii]
AID - 10.1007/s00604-023-05884-y [doi]
PST - epublish
SO  - Mikrochim Acta. 2023 Aug 15;190(9):352. doi: 10.1007/s00604-023-05884-y.