PMID- 37591434
OWN - NLM
STAT- Publisher
LR  - 20230826
IS  - 1879-0003 (Electronic)
IS  - 0141-8130 (Linking)
VI  - 251
DP  - 2023 Aug 15
TI  - Silk fibroin/polyvinyl alcohol composite film loaded with antibacterial 
      AgNP/polydopamine-modified montmorillonite; characterization and antibacterial 
      properties.
PG  - 126368
LID - S0141-8130(23)03264-6 [pii]
LID - 10.1016/j.ijbiomac.2023.126368 [doi]
AB  - In this study, a kind of nanocomposite film was fabricated via combining silk 
      fibroin, polyvinyl alcohol (SF/PVA) and AgNP/polydopamine-modified 
      Montmorillonite (AgNP/PDA-Mt). The structural characteristics and properties of 
      the SF/PVA/AgNP/PDA-Mt nanocomposites films were identified using X-ray 
      diffraction (XRD), Thermal gravimetric analyzer (TGA), Fourier transform infrared 
      spectroscopy (FTIR), EDS-mapping analyses and Scanning electron microscope (SEM). 
      The results indicated enhanced thermal performance of SF/PVA/AgNP/PDA-Mt 
      nanocomposites with increased AgNP/PDA-Mt weight. The nanocomposite film 
      exhibited excellent antibacterial activity against E. coli and S. aureus. The 2 % 
      SF/PVA/AgNP/PDA-Mt film showed the highest zone of inhibition with an average 
      inhibition circle diameter of 26.1 mm against E. coli and 20.61 mm against S. 
      aureus. Cytotoxicity test results indicated that the nanocomposites films were 
      biocompatible with L929 cells with a 100 % survival rate, which can be considered 
      as one of the advantages of new nanocomposites films. These findings suggest that 
      SF/PVA/AgNP/PDA-Mt films have potential clinical applications in wound dressing 
      and antibacterial biomedical applications.
CI  - Copyright (c) 2023. Published by Elsevier B.V.
FAU - Sun, Xuemei
AU  - Sun X
AD  - School of Food Science and Pharmaceutical Engineering, Nanjing normal university, 
      Nanjing, PR china.
FAU - Liang, Han
AU  - Liang H
AD  - School of Food Science and Pharmaceutical Engineering, Nanjing normal university, 
      Nanjing, PR china.
FAU - Wang, Huiyan
AU  - Wang H
AD  - School of Food Science and Pharmaceutical Engineering, Nanjing normal university, 
      Nanjing, PR china.
FAU - Meng, Na
AU  - Meng N
AD  - School of Food Science and Pharmaceutical Engineering, Nanjing normal university, 
      Nanjing, PR china. Electronic address: mengnafeiyu@163.com.
FAU - Jin, Suxing
AU  - Jin S
AD  - School of Food Science and Pharmaceutical Engineering, Nanjing normal university, 
      Nanjing, PR china. Electronic address: jinsuxing@njnu.edu.cn.
FAU - Zhou, Ninglin
AU  - Zhou N
AD  - Jiangsu Engineering Research Center for Biomedical Function Materials, Nanjing 
      Normal University, Nanjing 210046, China; Jiangsu Key Laboratory of Biofunctional 
      Materials, College of Chemistry and Materials Science, Nanjing Normal University, 
      Nanjing 210097, China. Electronic address: zhouninglin@njnu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20230815
PL  - Netherlands
TA  - Int J Biol Macromol
JT  - International journal of biological macromolecules
JID - 7909578
SB  - IM
OTO - NOTNLM
OT  - Antibacterial
OT  - Silk fibroin
OT  - Silver nanoparticles
COIS- Declaration of competing interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/08/18 00:42
MHDA- 2023/08/18 00:42
CRDT- 2023/08/17 19:20
PHST- 2023/05/21 00:00 [received]
PHST- 2023/08/12 00:00 [revised]
PHST- 2023/08/14 00:00 [accepted]
PHST- 2023/08/18 00:42 [pubmed]
PHST- 2023/08/18 00:42 [medline]
PHST- 2023/08/17 19:20 [entrez]
AID - S0141-8130(23)03264-6 [pii]
AID - 10.1016/j.ijbiomac.2023.126368 [doi]
PST - aheadofprint
SO  - Int J Biol Macromol. 2023 Aug 15;251:126368. doi: 10.1016/j.ijbiomac.2023.126368.