PMID- 37596447
OWN - NLM
STAT- MEDLINE
DCOM- 20240126
LR  - 20240206
IS  - 1573-2584 (Electronic)
IS  - 0301-1623 (Linking)
VI  - 56
IP  - 2
DP  - 2024 Feb
TI  - Association between controlling nutritional status score and chronic kidney 
      disease in diabetic patients: a cross-sectional study based on the National 
      Health and Nutrition Examination Survey.
PG  - 795-804
LID - 10.1007/s11255-023-03740-9 [doi]
AB  - PURPOSE: This study aimed to explore the association between controlling 
      nutritional status (CONUT) score and chronic kidney disease (CKD) in type-2 
      diabetes mellitus (T2DM) patients. METHODS: This was a cross-sectional study 
      based on the National Health and Nutrition Examination Survey (NHANES). The data 
      on demographic characteristics, physical examination, lifestyle behaviors, 
      comorbidities, medicine use, laboratory values, and energy were extracted. 
      Nutritional status was assessed using CONUT score, and patients were divided into 
      normal nutrition group and malnutrition group. Association between CONUT score 
      and CKD in T2DM patients was assessed using logistic regression analysis, and 
      odds ratio (OR) and 95% confidence intervals (CIs) were reported. Subgroup 
      analysis based on age, body mass index (BMI), cardiovascular disease (CVD), 
      diabetic retinopathy, and hyperlipidemia was performed. RESULTS: A total of 4581 
      patients were finally included for analysis. In the adjusted model, high CONUT 
      score was found to be associated with the high odds of CKD (OR = 1.28, 95% CI 
      1.05-1.56). Also, high CONUT score was associated with the high odds of CKD in 
      T2DM patients with age >/= 65 years, with BMI < 25 kg/m(2), with BMI >/= 25 kg/m(2), 
      without CVD, without diabetic retinopathy, with hyperlipidemia, or without 
      hyperlipidemia (all P < 0.05). CONCLUSIONS: Malnutrition was associated with the 
      high odds of CKD in T2DM patients, indicating that actively monitoring the 
      nutritional status is important for the management of CKD in T2DM patients.
CI  - (c) 2023. The Author(s), under exclusive licence to Springer Nature B.V.
FAU - Qu, Wei
AU  - Qu W
AD  - Department of General Medicine, The Second Hospital of Jilin University, No. 4026 
      Yatai Street, Nanguan District, Changchun, 130022, People's Republic of China.
FAU - Liu, Shanshan
AU  - Liu S
AD  - Department of General Medicine, The Second Hospital of Jilin University, No. 4026 
      Yatai Street, Nanguan District, Changchun, 130022, People's Republic of China.
FAU - Gu, Jinning
AU  - Gu J
AD  - Department of General Medicine, The Second Hospital of Jilin University, No. 4026 
      Yatai Street, Nanguan District, Changchun, 130022, People's Republic of China.
FAU - Wei, Xianyan
AU  - Wei X
AD  - Department of General Medicine, The Second Hospital of Jilin University, No. 4026 
      Yatai Street, Nanguan District, Changchun, 130022, People's Republic of China. 
      weixianyanccjilin@hotmail.com.
LA  - eng
PT  - Journal Article
DEP - 20230818
PL  - Netherlands
TA  - Int Urol Nephrol
JT  - International urology and nephrology
JID - 0262521
SB  - IM
MH  - Humans
MH  - Aged
MH  - Nutritional Status
MH  - Cross-Sectional Studies
MH  - Nutrition Surveys
MH  - *Diabetic Retinopathy/complications
MH  - Nutrition Assessment
MH  - *Malnutrition/complications
MH  - *Renal Insufficiency, Chronic/complications/epidemiology
MH  - *Diabetes Mellitus, Type 2/complications/epidemiology
MH  - *Cardiovascular Diseases/epidemiology/complications
MH  - *Hyperlipidemias
MH  - Retrospective Studies
MH  - Prognosis
OTO - NOTNLM
OT  - CONUT score
OT  - Chronic kidney disease
OT  - Malnutrition
OT  - Type-2 diabetes mellitus
EDAT- 2023/08/19 11:42
MHDA- 2024/01/26 06:43
CRDT- 2023/08/18 23:30
PHST- 2023/05/17 00:00 [received]
PHST- 2023/08/09 00:00 [accepted]
PHST- 2024/01/26 06:43 [medline]
PHST- 2023/08/19 11:42 [pubmed]
PHST- 2023/08/18 23:30 [entrez]
AID - 10.1007/s11255-023-03740-9 [pii]
AID - 10.1007/s11255-023-03740-9 [doi]
PST - ppublish
SO  - Int Urol Nephrol. 2024 Feb;56(2):795-804. doi: 10.1007/s11255-023-03740-9. Epub 
      2023 Aug 18.