PMID- 37597765
OWN - NLM
STAT- MEDLINE
DCOM- 20230907
LR  - 20230907
IS  - 1873-6351 (Electronic)
IS  - 0278-6915 (Linking)
VI  - 179
DP  - 2023 Sep
TI  - Persistent organic pollutants in Croatian breast milk: An overview of pollutant 
      levels and infant health risk assessment from 1976 to the present.
PG  - 113990
LID - S0278-6915(23)00392-7 [pii]
LID - 10.1016/j.fct.2023.113990 [doi]
AB  - This review article summarizes our research of persistent organic pollutants 
      (POPs) in human milk from Croatian mothers over the last few decades. Our studies 
      make up the bulk of all POPs research in human milk in Croatia and show a 
      state-of-the art in the research area. The first investigations were made in 
      1970's. Aim of our review article is to document the comprehensive results over 
      several decades as the best tool to: 1.) contribute to understanding of POPs and 
      their potential health risks, 2.) evaluate effectiveness of legislative bans and 
      restrictions on human exposure to POPs in Croatia, and 3.) to suggest further 
      actions. In our review we discuss: 1.) Human milk between 2011 and 2014 - 
      evaluation of interrelations of organochlorine pesticides (OCP) and 
      polychlorinated biphenyls (PCB) in human milk and their association with the 
      mother's age and parity using artificial intelligence methods; and our yet 
      unpublished research data on health risks for infants assessed through daily PCB 
      and OCP intake. 2.) Time trends of PCB and OCP in human milk between 1976 and 
      2014. 3.) polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofuran 
      (PCDD/F) in human milk in 2000., and yet unpublished data on PCDD/F and 
      polybrominated diphenyl ethers (PBDE) in 2014.
CI  - Copyright (c) 2023 Elsevier Ltd. All rights reserved.
FAU - Herceg Romanic, Snjezana
AU  - Herceg Romanic S
AD  - Institute for Medical Research and Occupational Health, Ksaverska Cesta 2, 10001, 
      Zagreb, Croatia.
FAU - Milicevic, Tijana
AU  - Milicevic T
AD  - Environmental Physics Laboratory, Institute of Physics Belgrade, National 
      Institute of the Republic of Serbia, University of Belgrade, Pregrevica 118, 
      11080, Belgrade, Serbia.
FAU - Jovanovic, Gordana
AU  - Jovanovic G
AD  - Environmental Physics Laboratory, Institute of Physics Belgrade, National 
      Institute of the Republic of Serbia, University of Belgrade, Pregrevica 118, 
      11080, Belgrade, Serbia; Singidunum University, Danijelova 32, 11000, Belgrade, 
      Serbia.
FAU - Matek Saric, Marijana
AU  - Matek Saric M
AD  - Department of Health Studies, University of Zadar, Splitska 1, 23000, Zadar, 
      Croatia.
FAU - Mendas, Gordana
AU  - Mendas G
AD  - Institute for Medical Research and Occupational Health, Ksaverska Cesta 2, 10001, 
      Zagreb, Croatia. Electronic address: gmendas@imi.hr.
FAU - Fingler, Sanja
AU  - Fingler S
AD  - Institute for Medical Research and Occupational Health, Ksaverska Cesta 2, 10001, 
      Zagreb, Croatia.
FAU - Jaksic, Goran
AU  - Jaksic G
AD  - Aquatika-Freshwater Aquarium Karlovac, Ulica Branka Cavlovica Cavleka 1/A, 47000, 
      Karlovac, Croatia.
FAU - Popovic, Aleksandar
AU  - Popovic A
AD  - University of Belgrade - Faculty of Chemistry, Studentski Trg 12-16, 11000, 
      Belgrade, Serbia.
FAU - Relic, Dubravka
AU  - Relic D
AD  - University of Belgrade - Faculty of Chemistry, Studentski Trg 12-16, 11000, 
      Belgrade, Serbia.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230817
PL  - England
TA  - Food Chem Toxicol
JT  - Food and chemical toxicology : an international journal published for the British 
      Industrial Biological Research Association
JID - 8207483
RN  - 0 (Persistent Organic Pollutants)
RN  - 0 (Environmental Pollutants)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
RN  - 0 (Polychlorinated Dibenzodioxins)
RN  - 0 (Pesticides)
SB  - IM
MH  - Female
MH  - Pregnancy
MH  - Infant
MH  - Humans
MH  - Milk, Human
MH  - Persistent Organic Pollutants
MH  - *Environmental Pollutants
MH  - Croatia
MH  - Artificial Intelligence
MH  - *Polychlorinated Biphenyls
MH  - *Polychlorinated Dibenzodioxins
MH  - *Pesticides
MH  - Risk Assessment
OTO - NOTNLM
OT  - Age
OT  - Machine learning
OT  - Parity
OT  - Persistent organic pollutants (POPs)
OT  - Risk assessment
OT  - Temporal trend
COIS- Declaration of competing interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/08/20 00:41
MHDA- 2023/09/07 06:42
CRDT- 2023/08/19 19:27
PHST- 2023/05/09 00:00 [received]
PHST- 2023/07/03 00:00 [revised]
PHST- 2023/08/14 00:00 [accepted]
PHST- 2023/09/07 06:42 [medline]
PHST- 2023/08/20 00:41 [pubmed]
PHST- 2023/08/19 19:27 [entrez]
AID - S0278-6915(23)00392-7 [pii]
AID - 10.1016/j.fct.2023.113990 [doi]
PST - ppublish
SO  - Food Chem Toxicol. 2023 Sep;179:113990. doi: 10.1016/j.fct.2023.113990. Epub 2023 
      Aug 17.