PMID- 37599363
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231121
IS  - 1758-5996 (Print)
IS  - 1758-5996 (Electronic)
IS  - 1758-5996 (Linking)
VI  - 15
IP  - 1
DP  - 2023 Aug 21
TI  - Sound touch elastography of Achilles tendons in patients with type 2 diabetes 
      mellitus versus healthy adults.
PG  - 174
LID - 10.1186/s13098-023-01148-0 [doi]
LID - 174
AB  - BACKGROUND: The studies of the effect of diabetes on the stiffness of Achilles 
      tendon (AT) tissue remain inconclusive, we believe it is necessary to find a 
      reliable method which can be used to detect the stiffness changes of the AT in 
      the diabetic state. The objective of the present study was to investigate the 
      effectiveness of sound touch elastography (STE) as a tool for detecting diabetic 
      Achilles tendinopathy. METHODS: We conducted a retrospective review of 180 
      participants, consisting of 82 patients with type 2 diabetes mellitus (T2DM) and 
      98 healthy adults, who had undergone AT ultrasonography. Young 's modulus (E) 
      values of the distal, middle, and proximal segments of bilateral ATs of all 
      participants were measured using STE technique. The E values of each AT segment 
      between the case and control group were compared. RESULTS: The E values of the 
      three segments of ATs in T2DM patients were lower than the healthy controls 
      (P < 0.05). In both groups, the E values of the distal segments were lower than 
      those of the middle segments, and the latter were lower than those of the 
      proximal segments (P < 0.05). The E value of each segment of AT was inversely 
      related to FPG, HbA1c, and diabetes duration (P < 0.05). The best cut-off points 
      for the E values of the three segments of the AT for detecting diabetic 
      tendinopathy were 347.44 kPa (AUC, 0.779), 441.57 kPa (AUC, 0.692), and 
      484.35 kPa (AUC, 0.676), respectively. CONCLUSION: STE can be used as a 
      complementary diagnostic tool for the diagnosis of diabetic Achilles 
      tendinopathy.
CI  - (c) 2023. BioMed Central Ltd., part of Springer Nature.
FAU - Huang, Xinxin
AU  - Huang X
AD  - Department of Ultrasonic Diagnosis, The Second Affiliated Hospital and Yuying 
      Children's Hospital of Wenzhou Medical University, 1111 Wenzhou Avenue, Longwan 
      District, Wenzhou, 325000, China.
FAU - Chen, Xingyu
AU  - Chen X
AD  - Department of Ultrasonic Diagnosis, The Second Affiliated Hospital and Yuying 
      Children's Hospital of Wenzhou Medical University, 1111 Wenzhou Avenue, Longwan 
      District, Wenzhou, 325000, China.
FAU - Chen, Xiu
AU  - Chen X
AD  - Department of Ultrasonic Diagnosis, The Second Affiliated Hospital and Yuying 
      Children's Hospital of Wenzhou Medical University, 1111 Wenzhou Avenue, Longwan 
      District, Wenzhou, 325000, China.
FAU - Chi, Ping
AU  - Chi P
AD  - Department of Ultrasonic Diagnosis, The Second Affiliated Hospital and Yuying 
      Children's Hospital of Wenzhou Medical University, 1111 Wenzhou Avenue, Longwan 
      District, Wenzhou, 325000, China.
FAU - Wang, Pengfei
AU  - Wang P
AD  - Department of Ultrasonic Diagnosis, The Second Affiliated Hospital and Yuying 
      Children's Hospital of Wenzhou Medical University, 1111 Wenzhou Avenue, Longwan 
      District, Wenzhou, 325000, China.
FAU - Zhan, Xiaomei
AU  - Zhan X
AD  - Department of Ultrasonic Diagnosis, The Second Affiliated Hospital and Yuying 
      Children's Hospital of Wenzhou Medical University, 1111 Wenzhou Avenue, Longwan 
      District, Wenzhou, 325000, China.
FAU - Zou, Chunpeng
AU  - Zou C
AD  - Department of Ultrasonic Diagnosis, The Second Affiliated Hospital and Yuying 
      Children's Hospital of Wenzhou Medical University, 1111 Wenzhou Avenue, Longwan 
      District, Wenzhou, 325000, China. chpzou@126.com.
FAU - Wang, Liang
AU  - Wang L
AD  - Department of Ultrasonic Diagnosis, The Second Affiliated Hospital and Yuying 
      Children's Hospital of Wenzhou Medical University, 1111 Wenzhou Avenue, Longwan 
      District, Wenzhou, 325000, China. wangliang_moon@126.com.
FAU - Dong, Yanyan
AU  - Dong Y
AD  - Department of Ultrasonic Diagnosis, The Second Affiliated Hospital and Yuying 
      Children's Hospital of Wenzhou Medical University, 1111 Wenzhou Avenue, Longwan 
      District, Wenzhou, 325000, China. yan217168@wzhealth.com.
LA  - eng
GR  - Project No. Y20210223/Wenzhou Municipal Science and Technology Bureau/
PT  - Journal Article
DEP - 20230821
PL  - England
TA  - Diabetol Metab Syndr
JT  - Diabetology & metabolic syndrome
JID - 101488958
PMC - PMC10440868
OTO - NOTNLM
OT  - Achilles tendon
OT  - Elasticity imaging technique
OT  - Sound touch elastography
OT  - Type 2 diabetes mellitus
COIS- The authors declare no competing interests. The authors declare that they have no 
      known competing financial interests or personal relationships that could have 
      appeared to influence the work reported in this paper.
EDAT- 2023/08/21 00:41
MHDA- 2023/08/21 00:42
PMCR- 2023/08/21
CRDT- 2023/08/20 23:14
PHST- 2023/06/28 00:00 [received]
PHST- 2023/08/05 00:00 [accepted]
PHST- 2023/08/21 00:42 [medline]
PHST- 2023/08/21 00:41 [pubmed]
PHST- 2023/08/20 23:14 [entrez]
PHST- 2023/08/21 00:00 [pmc-release]
AID - 10.1186/s13098-023-01148-0 [pii]
AID - 1148 [pii]
AID - 10.1186/s13098-023-01148-0 [doi]
PST - epublish
SO  - Diabetol Metab Syndr. 2023 Aug 21;15(1):174. doi: 10.1186/s13098-023-01148-0.