PMID- 37599518 OWN - NLM STAT- MEDLINE DCOM- 20240115 LR - 20240115 IS - 1878-6324 (Electronic) IS - 1053-8127 (Linking) VI - 37 IP - 1 DP - 2024 TI - Clinically significant effects of gait modification on knee pain: A systematic review and meta-analysis. PG - 3-12 LID - 10.3233/BMR-220291 [doi] AB - BACKGROUND: Knee pain is the main symptom of knee osteoarthritis. Walking is effective against knee pain, and some studies have shown that gait modification can also relieve this condition. However, the quality of evidence for the clinically significant effects of gait modification on knee pain has not been examined. OBJECTIVE: This systematic review and meta-analysis aimed to evaluate the level of evidence for the clinically significant effects of gait modification on knee pain and determine if the effects are greater than the minimal clinically important difference (MCID). METHODS: We comprehensively searched electronic databases such as MEDLINE, Cochrane Central Register of Controlled Trials, Physiotherapy Evidence Database, and Cumulative Index to Nursing and Allied Health Literature. Intervention studies with experimental groups who received gait modification and control groups who did not were evaluated. The Grading of Recommendations Assessment, Development and Evaluation system was used to assess the level of evidence. RESULTS: Nine studies met the inclusion criteria. All were included in the systematic review and two in the meta-analysis. Results showed that gait modification have significant effects (p= 0.02), and the quality of evidence was very low. However, several studies have revealed that the effects of gait modification, when used as a foot-focused intervention, were greater than the MCID. CONCLUSIONS: We concluded that there is a lack of high-quality evidence that supports the general efficacy of gait modification. Although based on low-quality evidence, when applied to the foot, it may have clinically significant effects. FAU - Tamura, Hiroyuki AU - Tamura H AD - Graduate School of Humanities and Social Sciences, Hiroshima University, Hiroshima, Japan. AD - Karada care Business Promotion Office, NEC Livex Ltd., Tokyo, Japan. FAU - Hirohama, Kenta AU - Hirohama K AD - Graduate School of Humanities and Social Sciences, Hiroshima University, Hiroshima, Japan. AD - Department of Rehabilitation, Sakamidorii Hospital, Hiroshima, Japan. FAU - Hamada, Kazuaki AU - Hamada K AD - Graduate School of Humanities and Social Sciences, Hiroshima University, Hiroshima, Japan. AD - Department of Rehabilitation, Wako Orthopedic Clinic, Hiroshima, Japan. FAU - Imura, Takeshi AU - Imura T AD - Department of Rehabilitation, Faculty of Health Sciences, Hiroshima Cosmopolitan University, Hiroshima, Japan. FAU - Mitsutake, Tsubasa AU - Mitsutake T AD - Department of Physical Therapy, Fukuoka International University of Health and Welfare, Fukuoka, Japan. FAU - Tanaka, Ryo AU - Tanaka R AD - Graduate School of Humanities and Social Sciences, Hiroshima University, Hiroshima, Japan. LA - eng PT - Journal Article PT - Meta-Analysis PT - Review PT - Systematic Review PL - Netherlands TA - J Back Musculoskelet Rehabil JT - Journal of back and musculoskeletal rehabilitation JID - 9201340 SB - IM MH - Humans MH - *Osteoarthritis, Knee/therapy/diagnosis MH - Walking MH - Pain MH - Gait OTO - NOTNLM OT - Osteoarthritis OT - minimal clinically important difference OT - walking EDAT- 2023/08/21 06:42 MHDA- 2024/01/15 12:42 CRDT- 2023/08/21 03:09 PHST- 2024/01/15 12:42 [medline] PHST- 2023/08/21 06:42 [pubmed] PHST- 2023/08/21 03:09 [entrez] AID - BMR220291 [pii] AID - 10.3233/BMR-220291 [doi] PST - ppublish SO - J Back Musculoskelet Rehabil. 2024;37(1):3-12. doi: 10.3233/BMR-220291.