PMID- 37603162
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240418
IS  - 2193-8245 (Print)
IS  - 2193-6528 (Electronic)
VI  - 12
IP  - 6
DP  - 2023 Dec
TI  - Management of Corneal Haze After Photorefractive Keratectomy.
PG  - 2841-2862
LID - 10.1007/s40123-023-00782-1 [doi]
AB  - Photorefractive keratectomy (PRK) is a safe and popular corneal surgery performed 
      worldwide. Nevertheless, there is potential risk of corneal haze development 
      after surgery. Proper management of post PRK haze is important for good visual 
      outcome. We performed a comprehensive review of the literature on the various 
      risk factors and treatments for PRK haze, searching the PubMed, Google Scholar, 
      SCOPUS, ScienceDirect, and Embase databases using relevant search terms. All 
      articles in English from August 1989 through April 2023 were reviewed for this 
      study, among which 102 articles were chosen to be included in the study. 
      Depending on the characteristics of and examination findings on post PRK haze, 
      different management options may be preferred. In the proposed framework, 
      management of PRK haze should include a full workup that includes patient's 
      subjective complaints and loss of vision as well as visual acuity, biomicroscopy, 
      anterior segment optical coherence tomography, epithelial mapping, and 
      Scheimpflug densitometry. Topical steroid treatment for haze should be stratified 
      based on early- or late-onset haze. Mechanical debridement or superficial 
      phototherapeutic keratectomy (PTK) may be used to treat superficial corneal haze. 
      Deep PTK and/or PRK can be used to treat deep corneal haze. Mitomycin-C and 
      topical steroids are prophylactic post-surgery agents to prevent recurrence of 
      haze.
CI  - (c) 2023. The Author(s).
FAU - Moshirfar, Majid
AU  - Moshirfar M
AUID- ORCID: 0000-0003-1024-6250
AD  - Hoopes Vision Research Center, Hoopes Vision, 11820 S. State St. #200, Draper, 
      UT, 84020, USA. cornea2020@me.com.
AD  - John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City, 
      UT, 84132, USA. cornea2020@me.com.
AD  - Utah Lions Eye Bank, Murray, UT, 84107, USA. cornea2020@me.com.
FAU - Wang, Qiancheng
AU  - Wang Q
AD  - Baylor College of Medicine, Houston, TX, 77030, USA.
FAU - Theis, Joshua
AU  - Theis J
AD  - University of Arizona College of Medicine-Phoenix, Phoenix, AZ, 85004, USA.
FAU - Porter, Kaiden C
AU  - Porter KC
AD  - University of Arizona College of Medicine-Phoenix, Phoenix, AZ, 85004, USA.
FAU - Stoakes, Isabella M
AU  - Stoakes IM
AD  - Hoopes Vision Research Center, Hoopes Vision, 11820 S. State St. #200, Draper, 
      UT, 84020, USA.
AD  - Pacific Northwest University of Health Sciences, Yakima, WA, 98901, USA.
FAU - Payne, Carter J
AU  - Payne CJ
AD  - Hoopes Vision Research Center, Hoopes Vision, 11820 S. State St. #200, Draper, 
      UT, 84020, USA.
AD  - Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
FAU - Hoopes, Phillip C
AU  - Hoopes PC
AD  - Hoopes Vision Research Center, Hoopes Vision, 11820 S. State St. #200, Draper, 
      UT, 84020, USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230821
PL  - England
TA  - Ophthalmol Ther
JT  - Ophthalmology and therapy
JID - 101634502
PMC - PMC10640498
OTO - NOTNLM
OT  - Corneal densitometry
OT  - Corneal haze
OT  - EBMD
OT  - Epithelial corneal map
OT  - LASEK
OT  - LASIK
OT  - Mechanical corneal debridement
OT  - Mitomycin-C
OT  - PRK
OT  - PTK
COIS- Majid Moshirfar, Qiancheng Wang, Josh S. Theis, Kaiden B. Porter, Isabella M. 
      Stoakes, Carter J. Payne, Phillip C. Hoopes have any conflicts of interest to 
      declare.
EDAT- 2023/08/21 12:42
MHDA- 2023/08/21 12:43
PMCR- 2023/08/21
CRDT- 2023/08/21 11:08
PHST- 2023/06/01 00:00 [received]
PHST- 2023/07/26 00:00 [accepted]
PHST- 2023/08/21 12:43 [medline]
PHST- 2023/08/21 12:42 [pubmed]
PHST- 2023/08/21 11:08 [entrez]
PHST- 2023/08/21 00:00 [pmc-release]
AID - 10.1007/s40123-023-00782-1 [pii]
AID - 782 [pii]
AID - 10.1007/s40123-023-00782-1 [doi]
PST - ppublish
SO  - Ophthalmol Ther. 2023 Dec;12(6):2841-2862. doi: 10.1007/s40123-023-00782-1. Epub 
      2023 Aug 21.