PMID- 37607036 OWN - NLM STAT- MEDLINE DCOM- 20230824 LR - 20230824 IS - 0034-8376 (Print) IS - 0034-8376 (Linking) VI - 75 IP - 4 DP - 2023 TI - Type 2 Diabetes Mellitus and Nonvalvular Atrial Fibrillation in Mexico: National Registries Raise a Red Flag. PG - 179-186 LID - 10.24875/RIC.23000056 [doi] AB - Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases worldwide and is highly prevalent in Mexico, as 10.2% of the adult population harbors this condition. T2DM is usually associated with cardiovascular comorbidities, including arrhythmias. Metabolic impairment is one of the mechanisms that contribute to tissue remodeling that affects atrial structure, and concomitant, the cardiac conduction system, both could result in atrial fibrillation (AF). AF is estimated to affect more than a half million Mexicans, and its incidence is expected to keep rising. According to national registries, T2DM is present in 28.4% of Mexican patients with AF and the coexistence of both diseases is associated with a higher risk of stroke. In clinical practice, the CHA(2)DS(2)-VASc risk score is useful for stroke risk stratification in patients with AF to facilitate the adequate use of anticoagulation therapy. T2DM is among the items of the CHA(2)DS(2)-VASc score because it correlates with an intrinsic prothrombotic state. In this narrative review, we present information that highlights the need for optimal glucose control and adequate anticoagulation in subjects with T2DM and AF. CI - Copyright: (c) 2023 Permanyer. FAU - Marquez-Murillo, Manlio F AU - Marquez-Murillo MF AD - Department of Cardiology, Centro Medico ABC, Mexico City, Mexico. FAU - Brenner-Muslera, Eduardo AU - Brenner-Muslera E AD - School of Medicine, Universidad Panamericana, Mexico City, Mexico. FAU - Rodriguez-Carrillo, Diana L AU - Rodriguez-Carrillo DL AD - Department of Cardiology, Centro Medico ABC, Mexico City, Mexico. FAU - Chua-Lopez, Cesar A AU - Chua-Lopez CA AD - Department of Cardiology, Centro Medico ABC, Mexico City, Mexico. FAU - Torres-Tamayo, Margarita AU - Torres-Tamayo M AD - Sociedad Mexicana de Nutricion y Endocrinologia, Mexico City, Mexico. LA - eng PT - Journal Article PT - Review PL - Mexico TA - Rev Invest Clin JT - Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion JID - 9421552 SB - IM MH - Adult MH - Humans MH - *Atrial Fibrillation/epidemiology MH - *Diabetes Mellitus, Type 2/complications/epidemiology MH - Mexico/epidemiology MH - Registries MH - *Stroke/epidemiology/etiology OTO - NOTNLM OT - Mexico OT - Nonvalvular atrial fibrillation OT - Oral anticoagulation OT - Stroke OT - Type 2 diabetes mellitus EDAT- 2023/08/22 18:42 MHDA- 2023/08/24 06:42 CRDT- 2023/08/22 12:43 PHST- 2023/08/24 06:42 [medline] PHST- 2023/08/22 18:42 [pubmed] PHST- 2023/08/22 12:43 [entrez] AID - j75/4/179 [pii] AID - 10.24875/RIC.23000056 [doi] PST - ppublish SO - Rev Invest Clin. 2023;75(4):179-186. doi: 10.24875/RIC.23000056.