PMID- 37609609
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230928
IS  - 0970-9134 (Print)
IS  - 0973-7723 (Electronic)
IS  - 0970-9134 (Linking)
VI  - 39
IP  - 5
DP  - 2023 Sep
TI  - Long-term outcomes of left ventricular posterior wall plication for ischemic 
      mitral regurgitation.
PG  - 462-470
LID - 10.1007/s12055-023-01527-2 [doi]
AB  - PURPOSE: To evaluate the early and long-term outcomes of left ventricular 
      posterior wall plication for ischemic mitral regurgitation. METHODS: Patients 
      with ischemic mitral regurgitation who underwent left ventricular posterior wall 
      plication via right-sided left atriotomy at our institution between 2010 and 2020 
      were retrospectively reviewed. Cases with normal cardiac function, left 
      ventricular end-systolic diameter < 50 mm, and left ventriculotomy approach were 
      excluded. RESULTS: The mean follow-up period was 5.3 years [standard deviation 
      (SD) = 3.5], with a maximum of 10 years. Among the 21 patients enrolled, 9 had 
      New York Heart Association (NYHA) class >/= III. Three patients required 
      preoperative inotrope support, while two preoperative ventilator support. The 
      mean left ventricular ejection fraction was 31.4% (SD: 8.6), and 16 patients had 
      mitral regurgitation grade >/= III. All patients underwent coronary artery bypass 
      grafting and mitral annuloplasty. Concomitant surgeries included 11 chordae 
      cutting and 3 tricuspid annuloplasties. One in-hospital death occurred due to 
      sepsis. At the follow-up, echocardiographic data showed significant improvement 
      in cardiac dilation and function and good control of mitral regurgitation. The 
      serum brain natriuretic peptide level was significantly reduced, and 85% of 
      patients improved to NYHA class I. Four deaths occurred later due to sudden, 
      unknown causes. The 5- and 8-year survival rates were 60.2% and 46.8%, 
      respectively, and the 5- and 8-year hospitalization rates due to heart failure 
      were 14.9% and 21.3%, respectively. CONCLUSION: The long-term outcomes of left 
      ventricular posterior wall plication were satisfactory for controlling heart 
      failure and improving survival rate and patient prognosis. SUPPLEMENTARY 
      INFORMATION: The online version contains supplementary material available at 
      10.1007/s12055-023-01527-2.
CI  - (c) Indian Association of Cardiovascular-Thoracic Surgeons 2023. Springer Nature or 
      its licensor (e.g. a society or other partner) holds exclusive rights to this 
      article under a publishing agreement with the author(s) or other rightsholder(s); 
      author self-archiving of the accepted manuscript version of this article is 
      solely governed by the terms of such publishing agreement and applicable law.
FAU - Nakamae, Kosuke
AU  - Nakamae K
AUID- ORCID: 0000-0003-3848-0153
AD  - Division of Cardiovascular Surgery, Saiseikai Kumamoto Hospital, 5-3-1, Chikami, 
      Minami-Ku, Kumamoto City, Kumamoto, 861-4193 Japan. GRID: grid.416612.6. ISNI: 
      0000 0004 1774 5826
FAU - Oshitomi, Takashi
AU  - Oshitomi T
AUID- ORCID: 0000-0001-8942-0981
AD  - Division of Cardiovascular Surgery, Saiseikai Kumamoto Hospital, 5-3-1, Chikami, 
      Minami-Ku, Kumamoto City, Kumamoto, 861-4193 Japan. GRID: grid.416612.6. ISNI: 
      0000 0004 1774 5826
FAU - Uesugi, Hideyuki
AU  - Uesugi H
AUID- ORCID: 0000-0002-6214-1373
AD  - Division of Cardiovascular Surgery, Saiseikai Kumamoto Hospital, 5-3-1, Chikami, 
      Minami-Ku, Kumamoto City, Kumamoto, 861-4193 Japan. GRID: grid.416612.6. ISNI: 
      0000 0004 1774 5826
FAU - Ideta, Ichiro
AU  - Ideta I
AD  - Division of Cardiovascular Surgery, Saiseikai Kumamoto Hospital, 5-3-1, Chikami, 
      Minami-Ku, Kumamoto City, Kumamoto, 861-4193 Japan. GRID: grid.416612.6. ISNI: 
      0000 0004 1774 5826
FAU - Takaji, Kentaro
AU  - Takaji K
AUID- ORCID: 0000-0001-9336-3860
AD  - Division of Cardiovascular Surgery, Saiseikai Kumamoto Hospital, 5-3-1, Chikami, 
      Minami-Ku, Kumamoto City, Kumamoto, 861-4193 Japan. GRID: grid.416612.6. ISNI: 
      0000 0004 1774 5826
FAU - Sassa, Toshiharu
AU  - Sassa T
AD  - Division of Cardiovascular Surgery, Saiseikai Kumamoto Hospital, 5-3-1, Chikami, 
      Minami-Ku, Kumamoto City, Kumamoto, 861-4193 Japan. GRID: grid.416612.6. ISNI: 
      0000 0004 1774 5826
FAU - Murata, Hidetaka
AU  - Murata H
AD  - Division of Cardiovascular Surgery, Saiseikai Kumamoto Hospital, 5-3-1, Chikami, 
      Minami-Ku, Kumamoto City, Kumamoto, 861-4193 Japan. GRID: grid.416612.6. ISNI: 
      0000 0004 1774 5826
FAU - Hirota, Masataka
AU  - Hirota M
AUID- ORCID: 0000-0001-6530-2841
AD  - Division of Cardiovascular Surgery, Saiseikai Kumamoto Hospital, 5-3-1, Chikami, 
      Minami-Ku, Kumamoto City, Kumamoto, 861-4193 Japan. GRID: grid.416612.6. ISNI: 
      0000 0004 1774 5826
LA  - eng
PT  - Journal Article
DEP - 20230603
PL  - India
TA  - Indian J Thorac Cardiovasc Surg
JT  - Indian journal of thoracic and cardiovascular surgery
JID - 8700105
PMC - PMC10442011
OTO - NOTNLM
OT  - Heart failure
OT  - Ischemic heart disease
OT  - Ischemic mitral regurgitation
OT  - Left ventricular posterior wall plication
OT  - Mitral valve repair
COIS- Competing interestsThe authors have no competing interests to declare that are 
      relevant to the content of this article.
EDAT- 2023/08/23 06:42
MHDA- 2023/08/23 06:43
PMCR- 2024/09/01
CRDT- 2023/08/23 04:22
PHST- 2023/01/04 00:00 [received]
PHST- 2023/04/19 00:00 [revised]
PHST- 2023/04/21 00:00 [accepted]
PHST- 2024/09/01 00:00 [pmc-release]
PHST- 2023/08/23 06:43 [medline]
PHST- 2023/08/23 06:42 [pubmed]
PHST- 2023/08/23 04:22 [entrez]
AID - 1527 [pii]
AID - 10.1007/s12055-023-01527-2 [doi]
PST - ppublish
SO  - Indian J Thorac Cardiovasc Surg. 2023 Sep;39(5):462-470. doi: 
      10.1007/s12055-023-01527-2. Epub 2023 Jun 3.