PMID- 37621300
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230826
IS  - 2378-8038 (Print)
IS  - 2378-8038 (Electronic)
IS  - 2378-8038 (Linking)
VI  - 8
IP  - 4
DP  - 2023 Aug
TI  - Treatment of sinus headache using a device that combines acoustic vibration with 
      oscillating expiratory pressure.
PG  - 839-846
LID - 10.1002/lio2.1124 [doi]
AB  - OBJECTIVE: To determine if simultaneous administration of acoustic vibration and 
      oscillating expiratory pressure affects the severity of facial pain among 
      patients with complaint of "sinus headache". METHODS: This is a prospective 
      single-arm observational study performed at a tertiary care medical center. 
      Subjects with complaint of sinus headache without evidence of chronic 
      rhinosinusitis on exam or computed tomography participated in a clinical study 
      applying simultaneous acoustic vibrations and positive expiratory pressure to the 
      nasal cavity twice daily over 4 weeks. Efficacy was assessed using three 
      validated pain metrics-pain visual analog scale (VAS), brief pain inventory-short 
      form (BPI-SF), and McGill pain questionnaire-short form (MPQ-SF). Device safety 
      and patient satisfaction were also assessed using questionnaires. RESULTS: 
      Twenty-nine patients (mean age 49 years, 55% female) completed the study without 
      any major adverse events. At the 4 week follow-up, facial pain VAS improved from 
      mean +/- SD of 59.6 +/- 15.7 to 34.6 +/- 21.7 (p < .001), BPI mean pain 
      (mean +/- standard deviation) improved from 4.4 +/- 2.0 to 2.9 +/- 1.9 (p = .007), and 
      MPQ-SF total improved from 12.2 +/- 6.5 to 6.5 +/- 5.2 (p < .001) with approximately 
      70% of patients achieving a minimal clinically important difference (MCID) across 
      all metrics. Additionally, pain VAS was assessed 5 min after a single use at 
      baseline with significant improvement (p < .001). Eighty-six percent of subjects 
      would both use device again and recommend it to others. CONCLUSIONS: Simultaneous 
      administration of acoustic vibration and oscillating expiratory pressure appears 
      to be a safe treatment for sinus headaches in patients without objective evidence 
      of chronic sinusitis. Results from this initial study are promising with regard 
      to efficacy in treatment of sinus headaches but will require further study. LEVEL 
      OF EVIDENCE: 2c.
CI  - (c) 2023 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley 
      Periodicals LLC on behalf of The Triological Society.
FAU - Miglani, Amar
AU  - Miglani A
AUID- ORCID: 0000-0002-0708-4345
AD  - Department of Otolaryngology-Head & Neck Surgery Medical University of South 
      Carolina Charleston South Carolina USA.
AD  - Division of Rhinology and Skull Base Surgery, Department of Otolaryngology-Head & 
      Neck Surgery Mayo Clinic Phoenix Arizona USA.
FAU - Germroth, Matthew
AU  - Germroth M
AD  - Department of Otolaryngology-Head & Neck Surgery Medical University of South 
      Carolina Charleston South Carolina USA.
FAU - LaPointe, Kristina A
AU  - LaPointe KA
AD  - Department of Otolaryngology-Head & Neck Surgery Medical University of South 
      Carolina Charleston South Carolina USA.
FAU - Nguyen, Shaun A
AU  - Nguyen SA
AUID- ORCID: 0000-0003-0664-4571
AD  - Department of Otolaryngology-Head & Neck Surgery Medical University of South 
      Carolina Charleston South Carolina USA.
FAU - Meyer, Ted A
AU  - Meyer TA
AD  - Department of Otolaryngology-Head & Neck Surgery Medical University of South 
      Carolina Charleston South Carolina USA.
LA  - eng
PT  - Journal Article
DEP - 20230728
PL  - United States
TA  - Laryngoscope Investig Otolaryngol
JT  - Laryngoscope investigative otolaryngology
JID - 101684963
PMC - PMC10446260
OTO - NOTNLM
OT  - facial pain
OT  - migraine headaches
OT  - sinogenic pain
OT  - sinus headaches
OT  - vibrational energy
COIS- None.
EDAT- 2023/08/25 06:42
MHDA- 2023/08/25 06:43
PMCR- 2023/07/28
CRDT- 2023/08/25 03:43
PHST- 2023/05/21 00:00 [received]
PHST- 2023/07/06 00:00 [revised]
PHST- 2023/07/16 00:00 [accepted]
PHST- 2023/08/25 06:43 [medline]
PHST- 2023/08/25 06:42 [pubmed]
PHST- 2023/08/25 03:43 [entrez]
PHST- 2023/07/28 00:00 [pmc-release]
AID - LIO21124 [pii]
AID - 10.1002/lio2.1124 [doi]
PST - epublish
SO  - Laryngoscope Investig Otolaryngol. 2023 Jul 28;8(4):839-846. doi: 
      10.1002/lio2.1124. eCollection 2023 Aug.