PMID- 37625530 OWN - NLM STAT- MEDLINE DCOM- 20240108 LR - 20240108 IS - 0003-4509 (Print) IS - 0003-4509 (Linking) VI - 82 IP - 1 DP - 2024 Jan TI - [Evaluation of the relevance of the pharmaceutical educational interview on the knowledge and satisfaction of patients who received a vagus nerve neurostimulator implantation]. PG - 163-173 LID - S0003-4509(23)00099-8 [pii] LID - 10.1016/j.pharma.2023.08.005 [doi] AB - INTRODUCTION: Vagal neurostimulation (VNS) medical devices (MDs) are used to treat drug-resistant epilepsy. Using a magnet, the patient can activate on the stimulations in order to stop a seizure or interrupt the adverse effects (AEs) of the device. The objective is to evaluate the improvement of the patients' knowledge about the VNS following a pharmaceutical educational interview (PEI) as well as their satisfaction. MATERIALS AND METHODS: The pharmaceutical educational interview regarding drugs and DMs was performed by the clinical pharmacist at the patient's bed after VNS implantation. A questionnaire about VNS devices (operation, adverse effects, recommendations) and assessing knowledge was submitted to patients before and after the PEI. Satisfaction was assessed by the Likert scale. RESULTS: From March 2020 to August 2021, 18 implanted patients were included in the study. In 78% of cases (14/18), the total number of good responses after PEI increased. The mean good response was significantly increased from 16.11/25 (64%) before PEI to 22.33/25 (89%) after PEI (P-value<0.01). The maximum satisfaction score (4/4) was given in 71% of the items. DISCUSSION-CONCLUSION: The results support the relevance of PEI. Patients feel a need for information and consider the interview useful. An improvement in knowledge was observed, which allows us to hope for an optimization of the effectiveness of the device, in particular, a reduction in seizures and AE. This study shows the feasibility and the interest of the development of clinical pharmacy applied to medical devices in complementarity with the expertise on drugs. CI - Copyright (c) 2023 Academie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights reserved. FAU - Marqueyssat, Gael-Sean AU - Marqueyssat GS AD - Pole pharmacie, equipe de pole neurosciences et cephalique, CHU de Toulouse, Toulouse, France. Electronic address: gs.marqueyssat@gmail.com. FAU - Valton, Luc AU - Valton L AD - Explorations neurophysiologiques, CHU de Purpan, Toulouse, France; Centre de recherche cerveau et cognition (CerCo), University of Toulouse, 31300 Toulouse, France. FAU - Civade, Elodie AU - Civade E AD - Pole pharmacie, equipe de pole neurosciences et cephalique, CHU de Toulouse, Toulouse, France. FAU - Laborde, Charlotte AU - Laborde C AD - Pole pharmacie, equipe de pole neurosciences et cephalique, I2MC equipe Ceramic, UFR Sante service de Pharmacie clinique, CHU de Toulouse, Toulouse, France. LA - fre PT - English Abstract PT - Journal Article TT - Evaluation de la pertinence de l'entretien pharmaceutique educatif sur les connaissances et la satisfaction de patients ayant beneficie d'une implantation d'un neurostimulateur du nerf vague. DEP - 20230823 PL - France TA - Ann Pharm Fr JT - Annales pharmaceutiques francaises JID - 2985176R RN - 0 (Pharmaceutical Preparations) SB - IM MH - Humans MH - Patient Satisfaction MH - *Vagus Nerve Stimulation/adverse effects/methods MH - *Drug Resistant Epilepsy/etiology/therapy MH - *Drug-Related Side Effects and Adverse Reactions MH - Vagus Nerve MH - Pharmaceutical Preparations MH - Treatment Outcome MH - Retrospective Studies OTO - NOTNLM OT - Entretiens pharmaceutiques OT - Epilepsy OT - Implantable neurostimulator OT - Neurochirurgie OT - Neurostimulateurs implantables OT - Neurostimulation du nerf vague OT - Neurosurgery OT - Pharmaceutical services OT - Pharmacie OT - Pharmacy OT - Vagus nerve stimulation OT - Epilepsie EDAT- 2023/08/26 05:42 MHDA- 2024/01/08 06:42 CRDT- 2023/08/25 19:26 PHST- 2023/04/05 00:00 [received] PHST- 2023/07/11 00:00 [revised] PHST- 2023/08/21 00:00 [accepted] PHST- 2024/01/08 06:42 [medline] PHST- 2023/08/26 05:42 [pubmed] PHST- 2023/08/25 19:26 [entrez] AID - S0003-4509(23)00099-8 [pii] AID - 10.1016/j.pharma.2023.08.005 [doi] PST - ppublish SO - Ann Pharm Fr. 2024 Jan;82(1):163-173. doi: 10.1016/j.pharma.2023.08.005. Epub 2023 Aug 23.