PMID- 37629620 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230829 IS - 2075-1729 (Print) IS - 2075-1729 (Electronic) IS - 2075-1729 (Linking) VI - 13 IP - 8 DP - 2023 Aug 17 TI - Predictors of Quality-of-Life Improvement at Different Minimum Clinically Important Difference Values in Patients with Chronic Obstructive Pulmonary Disease after Climatic Rehabilitation Treatment. LID - 10.3390/life13081763 [doi] LID - 1763 AB - BACKGROUND: The minimum clinically important difference (MCID) for the St George's Respiratory Questionnaire (SGRQ) is debated in chronic obstructive pulmonary disease (COPD) quality-of-life (QoL) assessments. This study aimed to determine whether there is a difference in predictors of clinically significant improvement between the traditional (value of 4) and newly proposed MCID SGRQ (value of 7) after climatic rehabilitation treatment. Climatic rehabilitation treatment consists of two main parts: climatotherapy, which typically involves the controlled exposure of individuals to natural environmental elements, and climatic rehabilitation, which includes other therapeutic factors such as physical activities as well as educating the patient to change their lifestyle. METHODS: This study included 90 consecutive patients diagnosed with COPD who underwent structured complex pulmonary rehabilitation in High Tatras, part of the Carpathian Mountains. The examination before and after treatment included spirometry, QoL assessment using the SGRQ, 6 min walk test (6-MWT), and the Borg, Beck and Zung scale. RESULTS: Patients showed statistically significant improvement after the intervention in FEV1, FEV1/FVC, 6-MWT, (p < 0.001), anxiety scores, depression, and improvement in dyspnoea both before and after the 6-MWT (p < 0.001). For both MCID for SGRQ levels 4 and 7, we confirmed the same predictors of clinical improvement for bronchial obstruction grade (spirometry) and exercise capacity (6-MWT), for quality of life in activity score and total score. CONCLUSION: The results suggest that both the proposed MCID for SGRQ values could be sufficient to assess the clinical significance of the achieved change in health status when assessing the need for pulmonary rehabilitation comprising climatotherapy in patients with COPD. FAU - Kubincova, Anna AU - Kubincova A AD - Department of Physical Medicine, Balneology and Medical Rehabilitation, Medical Faculty of P. J. Safarik University and L. Pasteur University Hospital in Kosice, 04190 Kosice, Slovakia. FAU - Takac, Peter AU - Takac P AUID- ORCID: 0000-0002-6615-1894 AD - Department of Physical Medicine, Balneology and Medical Rehabilitation, Medical Faculty of P. J. Safarik University and L. Pasteur University Hospital in Kosice, 04190 Kosice, Slovakia. FAU - Demjanovic Kendrova, Lucia AU - Demjanovic Kendrova L AD - Department of Physiotherapy, Faculty of Health Care, University of Presov, 08001 Presov, Slovakia. FAU - Joppa, Pavol AU - Joppa P AD - Department of Pneumology and Phtiseology, Medical Faculty of P. J. Safarik University and L. Pasteur University Hospital in Kosice, 04190 Kosice, Slovakia. LA - eng PT - Journal Article DEP - 20230817 PL - Switzerland TA - Life (Basel) JT - Life (Basel, Switzerland) JID - 101580444 PMC - PMC10455286 OTO - NOTNLM OT - COPD OT - climatic rehabilitation OT - climatotherapy OT - minimum clinically important difference (MCID) quality of life (SGRQ) OT - pulmonary rehabilitation COIS- The authors declare no conflict of interest. EDAT- 2023/08/26 10:45 MHDA- 2023/08/26 10:46 PMCR- 2023/08/17 CRDT- 2023/08/26 01:20 PHST- 2023/06/30 00:00 [received] PHST- 2023/08/13 00:00 [revised] PHST- 2023/08/15 00:00 [accepted] PHST- 2023/08/26 10:46 [medline] PHST- 2023/08/26 10:45 [pubmed] PHST- 2023/08/26 01:20 [entrez] PHST- 2023/08/17 00:00 [pmc-release] AID - life13081763 [pii] AID - life-13-01763 [pii] AID - 10.3390/life13081763 [doi] PST - epublish SO - Life (Basel). 2023 Aug 17;13(8):1763. doi: 10.3390/life13081763.