PMID- 37630773 OWN - NLM STAT- MEDLINE DCOM- 20230828 LR - 20230829 IS - 2072-6643 (Electronic) IS - 2072-6643 (Linking) VI - 15 IP - 16 DP - 2023 Aug 15 TI - Functional Food in Relation to Gastroesophageal Reflux Disease (GERD). LID - 10.3390/nu15163583 [doi] LID - 3583 AB - Gastroesophageal reflux disease (GERD) is a common esophageal disorder characterized by troublesome symptoms associated with increased esophageal acid exposure. The cornerstones of therapy in this regard include treatment with acid-suppressive agents, lifestyle modifications, and dietary therapy, although the latter has not been well defined. As concerns regarding long-term proton pump inhibitor (PPI) use continue to be explored, patients and healthcare providers are becoming increasingly interested in the role of diet in disease management. However, dietary interventions lack evidence of the synthesis effect of functional foods. The following is a review of dietary therapy for GERD, emphasizing food components' impact on GERD pathophysiology and management. Although the sequential dietary elimination of food groups is a common practice, the literature supports broader intervention, including reduced overall sugar intake, increased dietary fiber, and changes in overall eating practices. While the primary concern of food companies is to provide safe products, the caloric, nutritional, and functional composition of foods is also generating interest in the food industry due to consumers' concerns. FAU - Herdiana, Yedi AU - Herdiana Y AUID- ORCID: 0000-0001-5831-9389 AD - Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, Indonesia. LA - eng PT - Journal Article PT - Review DEP - 20230815 PL - Switzerland TA - Nutrients JT - Nutrients JID - 101521595 RN - 0 (Dietary Fiber) SB - IM MH - Humans MH - Functional Food MH - *Gastroesophageal Reflux/therapy MH - *Esophageal Diseases MH - Behavior Therapy MH - Dietary Fiber PMC - PMC10458865 OTO - NOTNLM OT - dietary treatment OT - esophageal disorder OT - food industry OT - lifestyle modifications OT - long-term PPI OT - processing technology COIS- The author declares no conflict of interest. EDAT- 2023/08/26 10:46 MHDA- 2023/08/28 06:42 PMCR- 2023/08/15 CRDT- 2023/08/26 01:27 PHST- 2023/07/23 00:00 [received] PHST- 2023/08/01 00:00 [revised] PHST- 2023/08/04 00:00 [accepted] PHST- 2023/08/28 06:42 [medline] PHST- 2023/08/26 10:46 [pubmed] PHST- 2023/08/26 01:27 [entrez] PHST- 2023/08/15 00:00 [pmc-release] AID - nu15163583 [pii] AID - nutrients-15-03583 [pii] AID - 10.3390/nu15163583 [doi] PST - epublish SO - Nutrients. 2023 Aug 15;15(16):3583. doi: 10.3390/nu15163583.