PMID- 37633882 OWN - NLM STAT- MEDLINE DCOM- 20230914 LR - 20231121 IS - 1477-7525 (Electronic) IS - 1477-7525 (Linking) VI - 21 IP - 1 DP - 2023 Aug 26 TI - Health-related quality of life in Chinese individuals with type 2 diabetes mellitus: a multicenter cross-sectional study. PG - 100 LID - 10.1186/s12955-023-02183-1 [doi] LID - 100 AB - BACKGROUND: Type 2 diabetes mellitus (T2DM) is a chronic and life-threatening disease. Health-related quality of life (HRQoL) is vital for individuals with T2DM. However, little is known about the impact of psychological stability factors on HRQoL among individuals with T2DM in mainland China. METHODS: This multicenter cross-sectional study was conducted in five tertiary grade-A hospitals in Chongqing, China, from January to December 2019. A total of 385 individuals with T2DM were included by the convenient sample method. Fear of Progression (FOP) Questionnaire-short Form, Hypoglycemia Fear Survey II, diabetes-management self-efficacy scale, and EuroQol-5 Dimensions were used for data collection. RESULTS: The mean age of the 385 individuals was 57.65 (SD = 15.15) years, three-quarters of whom had a high school or above education level. The participants in our study had moderate HRQoL and were more likely to have poor scores in the pain/discomfort dimension. The FOP level was moderate on average, and 23.1% of individuals suffered from psychological dysfunction. The participants had higher levels of fear of hypoglycemia (FOH) and self-efficacy (SE). Multiple steppage-regression analysis predicted that higher levels of FOP and FOH, reduced SE, older age, longer duration since diagnosis, lower educational attainment, higher levels of HbA1c, and living with comorbid conditions were related to lower HRQoL. CONCLUSION: This study showed that the HRQoL among Chinese T2DM patients may be impaired by increased FOP and FOH, decreased SE, and poor glycemic control. In addition, as the patient's age and duration since diagnosis increase, their HRQoL further declines. We recommend improving HRQoL by encouraging individuals to attain more health education and resilience skills to enhance SE and reduce negative emotions among individuals with T2DM. CI - (c) 2023. BioMed Central Ltd., part of Springer Nature. FAU - Zeng, Zihuan AU - Zeng Z AD - Institute of Burn Research, The First Affiliated Hospital of Army Medical University, Chongqing, 400038, China. AD - School of Nursing, Chongqing Medical University, Chongqing, 400016, China. FAU - Wang, Xingli AU - Wang X AD - Institute of Burn Research, The First Affiliated Hospital of Army Medical University, Chongqing, 400038, China. FAU - Chen, Yanhan AU - Chen Y AD - School of Nursing, Chongqing Medical University, Chongqing, 400016, China. FAU - Zhou, Hengyu AU - Zhou H AD - School of Nursing, Chongqing Medical University, Chongqing, 400016, China. FAU - Zhu, Wenfen AU - Zhu W AD - School of Nursing, Chongqing Medical University, Chongqing, 400016, China. FAU - Xiong, Xiu AU - Xiong X AD - Department of Dermatology, University-Town Hospital of Chongqing Medical University, Chongqing, China. FAU - Tang, Jiao AU - Tang J AD - School of Nursing, Chongqing Medical University, Chongqing, 400016, China. tangjiao9209@cqmu.edu.cn. AD - Department of Nursing, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. tangjiao9209@cqmu.edu.cn. FAU - Zhao, Qinghua AU - Zhao Q AD - Department of Nursing, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. qh20063@163.com. LA - eng GR - CSTC2021jscx-gksb-N0021/Chongqing Science and Technology Commission/ GR - CSTC2021jscx-gksb-N0021/Chongqing Science and Technology Commission/ PT - Journal Article PT - Multicenter Study DEP - 20230826 PL - England TA - Health Qual Life Outcomes JT - Health and quality of life outcomes JID - 101153626 SB - IM MH - Humans MH - Middle Aged MH - Cross-Sectional Studies MH - *Diabetes Mellitus, Type 2 MH - East Asian People MH - *Hypoglycemia MH - Quality of Life MH - Adult MH - Aged PMC - PMC10464323 OTO - NOTNLM OT - Fear of hypoglycemia OT - Fear of progression OT - Health-related quality of life OT - Self-efficacy OT - Type 2 diabetes mellitus COIS- The authors declare no competing interests. EDAT- 2023/08/27 05:43 MHDA- 2023/08/28 06:43 PMCR- 2023/08/26 CRDT- 2023/08/26 23:12 PHST- 2023/03/11 00:00 [received] PHST- 2023/08/15 00:00 [accepted] PHST- 2023/08/28 06:43 [medline] PHST- 2023/08/27 05:43 [pubmed] PHST- 2023/08/26 23:12 [entrez] PHST- 2023/08/26 00:00 [pmc-release] AID - 10.1186/s12955-023-02183-1 [pii] AID - 2183 [pii] AID - 10.1186/s12955-023-02183-1 [doi] PST - epublish SO - Health Qual Life Outcomes. 2023 Aug 26;21(1):100. doi: 10.1186/s12955-023-02183-1.