PMID- 37636287 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230829 IS - 2398-8835 (Electronic) IS - 2398-8835 (Linking) VI - 6 IP - 8 DP - 2023 Aug TI - Prevalence, knowledge, and lifestyle-associated risk factors of dyslipidemia among Ghanaian type-2 diabetes mellitus patients in rural and urban areas: A multicenter cross-sectional study. PG - e1475 LID - 10.1002/hsr2.1475 [doi] LID - e1475 AB - BACKGROUND AND AIMS: Dyslipidemia in diabetes mellitus has been linked to unhealthy lifestyle and bad eating habits. However, this association has not been well studied among rural and urban Ghanaian populations. In this study, we determined the prevalence, knowledge, and lifestyle-associated risk factors of dyslipidemia among Ghanaian type-2 diabetes mellitus (T2DM) patients in rural and urban areas. METHODS: This comparative multicentre-cross-sectional study recruited 228 T2DM outpatients attending the St. Michael Hospital, Pramso (rural) and Kumasi South Regional Hospital (urban), Ghana for routine check-ups. Self-structured questionnaire was used to collect sociodemographic, knowledge, and lifestyle characteristics. Fasting blood samples were taken to measure lipid profiles. Dyslipidemia was defined per the American Diabetes Association criteria. All p < 0.05 were considered statistically significant. RESULTS: The overall prevalence of dyslipidemia was 79/228 (34.7%). Dyslipidemia was more prevalent among urban participants 43 (18.9%) than rural participants 36 (15.8%). Twenty-seven (11.7%) had adequate knowledge about the risk factors, complications, and management of diabetes. Eating supper after 7 p.m. [adjusted odds ratio = 3.77, 95% confidence interval (1.70-8.37), p = 0.001] significantly increased one's risk of having dyslipidemia by 3.8-fold compared to eating supper earlier (before 5 p.m.). CONCLUSION: Dyslipidemia is increasing among T2DM patients in both urban and rural areas and it's independently influenced by eating supper after 7 p.m. Most participants were ignorant of the risk factors, complications, and management of diabetes. Adjusting eating habits and increasing diabetes awareness programs to sensitize the general public can mitigate the increasing prevalence of dyslipidemia in both urban and rural areas. CI - (c) 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC. FAU - Boadu, Wina I O AU - Boadu WIO AUID- ORCID: 0000-0002-2660-1707 AD - Department of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana. FAU - Anto, Enoch O AU - Anto EO AUID- ORCID: 0000-0001-9023-6612 AD - Department of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana. AD - School of Medical and Health Sciences Edith Cowan University Perth Australia. AD - Centre for Precision Health, ECU Strategic Research Centre Edith Cowan University Perth Australia. FAU - Frimpong, Joseph AU - Frimpong J AUID- ORCID: 0000-0002-9128-7208 AD - Department of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana. FAU - Ntiful, Felix AU - Ntiful F AD - Department of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana. FAU - Korsah, Emmanuel E AU - Korsah EE AD - Department of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana. FAU - Ansah, Ezekiel AU - Ansah E AD - Department of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana. FAU - Tamakloe, Valentine C K T AU - Tamakloe VCKT AUID- ORCID: 0000-0002-2411-6441 AD - Department of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana. FAU - Agyapomaa, Afia AU - Agyapomaa A AD - Department of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana. FAU - Opoku, Stephen AU - Opoku S AD - Department of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana. FAU - Senu, Ebenezer AU - Senu E AUID- ORCID: 0000-0002-2973-8952 AD - Department of Molecular Medicine, School of Medicine and Dentistry Kwame Nkrumah University of Science and Technology Kumasi Ghana. FAU - Nyantakyi, Michael AU - Nyantakyi M AUID- ORCID: 0000-0003-3864-0604 AD - Department of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana. FAU - Etwi-Mensah, Albright AU - Etwi-Mensah A AD - Department of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana. FAU - Acheampong, Emmanuel AU - Acheampong E AD - School of Medical and Health Sciences Edith Cowan University Perth Australia. AD - Department of Molecular Medicine, School of Medicine and Dentistry Kwame Nkrumah University of Science and Technology Kumasi Ghana. FAU - Boadu, Kwame O AU - Boadu KO AD - Department of Obstetrics and Gynaecology, Kumasi South Hospital Atonsu-Agogo Kumasi Ghana. FAU - Donkoh, Emmanuel Timmy AU - Donkoh ET AUID- ORCID: 0000-0002-7476-4578 AD - Department of Medical Laboratory Science University of Energy and Natural Resources Sunyani Ghana. FAU - Obirikorang, Christian AU - Obirikorang C AD - Department of Molecular Medicine, School of Medicine and Dentistry Kwame Nkrumah University of Science and Technology Kumasi Ghana. LA - eng PT - Journal Article DEP - 20230823 PL - United States TA - Health Sci Rep JT - Health science reports JID - 101728855 PMC - PMC10447875 OTO - NOTNLM OT - dyslipidemia OT - risk factors OT - rural OT - type-2 diabetes mellitus OT - urban COIS- The authors declare no conflict of interest. EDAT- 2023/08/28 06:43 MHDA- 2023/08/28 06:44 PMCR- 2023/08/23 CRDT- 2023/08/28 04:34 PHST- 2023/04/30 00:00 [received] PHST- 2023/07/09 00:00 [revised] PHST- 2023/07/23 00:00 [accepted] PHST- 2023/08/28 06:44 [medline] PHST- 2023/08/28 06:43 [pubmed] PHST- 2023/08/28 04:34 [entrez] PHST- 2023/08/23 00:00 [pmc-release] AID - HSR21475 [pii] AID - 10.1002/hsr2.1475 [doi] PST - epublish SO - Health Sci Rep. 2023 Aug 23;6(8):e1475. doi: 10.1002/hsr2.1475. eCollection 2023 Aug.