PMID- 37636313 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230829 IS - 2297-055X (Print) IS - 2297-055X (Electronic) IS - 2297-055X (Linking) VI - 10 DP - 2023 TI - Left atrial appendage aneurysm in pediatrics: Case study and literature review. PG - 1211619 LID - 10.3389/fcvm.2023.1211619 [doi] LID - 1211619 AB - Left atrial appendage aneurysm (LAAA) is a rare cardiac pathology that is often identified in adulthood. There are a myriad of presentations related to atrial appendage enlargement, but most are asymptomatic. Pediatric cases of LAAA are extremely rare. We report a case of an incidental giant LAAA found in a healthy 6-year-old boy. He was successfully treated with surgical resection. A review of the literature shows that the presentation of LAAA in pediatrics likely involves cardiac or respiratory symptoms but can also be incidental findings. Similar to adults, diagnosis requires cardiac imaging, with echocardiography being the mainstay. Surgical intervention is indicated in symptomatic and most asymptomatic patients to prevent complications. More research is warranted into the optimal timing of surgery and alternative surgical approaches for complex cases. CI - (c) 2023 Norozi, Subasri, Diaz and Honjo. FAU - Norozi, Kambiz AU - Norozi K AD - Department of Paediatrics, University of Western Ontario, London, ON, Canada. AD - Division of Pediatric Cardiology, Department of Paediatrics, London Health Sciences Centre, London, ON, Canada. AD - Pediatric Cardiopulmonary Research Laboratory, London Health Sciences Centre, London, ON, Canada. AD - Children Health Research Institute, London, ON, Canada. AD - Department of Paediatric Cardiology, Medical School Hannover, Hannover, Germany. FAU - Subasri, Mathushan AU - Subasri M AD - Division of Pediatric Cardiology, Department of Paediatrics, London Health Sciences Centre, London, ON, Canada. AD - Pediatric Cardiopulmonary Research Laboratory, London Health Sciences Centre, London, ON, Canada. AD - Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada. FAU - Diaz, Luis Altamirano AU - Diaz LA AD - Department of Paediatrics, University of Western Ontario, London, ON, Canada. AD - Division of Pediatric Cardiology, Department of Paediatrics, London Health Sciences Centre, London, ON, Canada. AD - Pediatric Cardiopulmonary Research Laboratory, London Health Sciences Centre, London, ON, Canada. AD - Children Health Research Institute, London, ON, Canada. FAU - Honjo, Osami AU - Honjo O AD - Department of Surgery, The Hospital for Sick Children, Toronto, ON, Canada. LA - eng PT - Case Reports DEP - 20230810 PL - Switzerland TA - Front Cardiovasc Med JT - Frontiers in cardiovascular medicine JID - 101653388 PMC - PMC10449248 OTO - NOTNLM OT - case report OT - left atrial appendage aneurysm OT - literature review OT - pediatric cardiac surgery OT - pediatric cardiology COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2023/08/28 06:43 MHDA- 2023/08/28 06:44 PMCR- 2023/01/01 CRDT- 2023/08/28 04:34 PHST- 2023/04/25 00:00 [received] PHST- 2023/07/28 00:00 [accepted] PHST- 2023/08/28 06:44 [medline] PHST- 2023/08/28 06:43 [pubmed] PHST- 2023/08/28 04:34 [entrez] PHST- 2023/01/01 00:00 [pmc-release] AID - 10.3389/fcvm.2023.1211619 [doi] PST - epublish SO - Front Cardiovasc Med. 2023 Aug 10;10:1211619. doi: 10.3389/fcvm.2023.1211619. eCollection 2023.