PMID- 37637881
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230829
IS  - 2691-3593 (Electronic)
IS  - 2691-3593 (Linking)
VI  - 2
IP  - 4
DP  - 2021 Dec
TI  - Short-term Results of Transit Bipartition to Promote Weight Loss After 
      Laparoscopic Sleeve Gastrectomy.
PG  - e102
LID - 10.1097/AS9.0000000000000102 [doi]
AB  - OBJECTIVE: To evaluate (1) the efficacy of transit bipartition (TB) as revisional 
      bariatric surgery (RBS) after laparoscopic sleeve gastrectomy (LSG); (2) the 
      impact of the length of the common channel (CC) on weight loss. BACKGROUND: LSG 
      in combination with TB has been shown to be highly efficacious for treating 
      morbid obesity. The role of TB as RBS to address the problem of primary failure 
      or weight recidivism after LSG is less well defined. METHODS: Observational study 
      of outcomes in 100 morbidly obese patients who received a TB following LSG. 
      Follow-up examinations (FE) were performed at 1, 3, 6, and 12 months. Variables 
      analyzed included BMI, percent excess weight loss (%EWL), total body weight loss 
      (%TBWL), effect on obesity-related conditions and complications. RESULTS: The 
      mean BMI before LSG was 49.9 +/- 8.5 kg/m(2). A nadir of 32.7 +/- 6.1 kg/m(2) was 
      reached 22.1 +/- 16.9 months after LSG (%EWL 70.0 +/- 14.5). The time interval 
      between LSG and TB was 52.2 +/- 26.6 months at which the BMI had increased to 37.6 
      +/- 7.1 kg/m(2) and %EWL decreased to 49.4 +/- 19.7. Following TB, the BMI decreased 
      continuously to 31.4 +/- 5.7 kg/m(2) after 12 months with a parallel increase in 
      %EWL to 74.7 +/- 20.3 and %TWL reaching 36.3 +/- 10.5. Weight loss was significantly 
      higher for CC length of 250 versus 300 cm after 12 months (BMI 29.4 +/- 5.3/33 +/- 
      5.3 kg/m(2), P = 0.002; %EWL 79.8 +/- 26.6/70.4 +/- 17; P = 0.009). Improvement of 
      comorbidities was observed in a high proportion of patients. Major early 
      complications occurred in 3% of the patients. CONCLUSION: TB is an effective 
      second-step procedure to address insufficient weight loss or weight recidivism 
      after LSG. CC length of 250 versus 300 cm had a significant impact. While most 
      improvements of obesity-related comorbidities are likely linked to weight loss, 
      amelioration of GERD is largely mediated by accelerated gastric emptying. Major 
      complications were observed in 3% of patients and managed without fatalities.
CI  - Copyright (c) 2021 The Author(s). Published by Wolters Kluwer Health, Inc.
FAU - Reiser, Markus
AU  - Reiser M
AD  - Department of Gastroenterology, Klinikum-Vest GmbH, Paracelsus-klinik Marl, Marl, 
      Germany.
FAU - Christogianni, Vasiliki
AU  - Christogianni V
AD  - Department of Surgery, Klinikum Vest GmbH, Knappschaftskrankenhaus 
      Recklinghausen, Recklinghausen, Germany.
FAU - Nehls, Fabian
AU  - Nehls F
AD  - Department of Surgery, Klinikum Vest GmbH, Knappschaftskrankenhaus 
      Recklinghausen, Recklinghausen, Germany.
FAU - Dukovska, Radostina
AU  - Dukovska R
AD  - Department of Surgery, Klinikum Vest GmbH, Knappschaftskrankenhaus 
      Recklinghausen, Recklinghausen, Germany.
FAU - de la Cruz, Marlon
AU  - de la Cruz M
AD  - Department of Surgery, Klinikum Vest GmbH, Knappschaftskrankenhaus 
      Recklinghausen, Recklinghausen, Germany.
FAU - Busing, Martin
AU  - Busing M
AD  - Department of Surgery, Klinikum Vest GmbH, Knappschaftskrankenhaus 
      Recklinghausen, Recklinghausen, Germany.
LA  - eng
PT  - Journal Article
DEP - 20211001
PL  - United States
TA  - Ann Surg Open
JT  - Annals of surgery open : perspectives of surgical history, education, and 
      clinical approaches
JID - 101769928
PMC - PMC10455425
OTO - NOTNLM
OT  - gastro-esophageal reflux disease
OT  - hypoabsorptive surgery
OT  - laparoscopic sleeve gastrectomy
OT  - revisional bariatric surgery
OT  - single anastomosis sleeve-ileal bypass
OT  - transit bipartition
OT  - weight recidivism
OT  - weight regain
COIS- M.R. acted as a consultant for Adivo Associates Germany and received speaker fees 
      from Hitachi Medical Systems and Abbvie GmbH & Co K.G. M.B. received speaker fees 
      from Medtronic and Gore. The remaining authors have nothing to disclose.
EDAT- 2021/10/01 00:00
MHDA- 2021/10/01 00:01
PMCR- 2021/10/01
CRDT- 2023/08/28 04:55
PHST- 2021/05/05 00:00 [received]
PHST- 2021/09/04 00:00 [accepted]
PHST- 2021/10/01 00:01 [medline]
PHST- 2021/10/01 00:00 [pubmed]
PHST- 2023/08/28 04:55 [entrez]
PHST- 2021/10/01 00:00 [pmc-release]
AID - 10.1097/AS9.0000000000000102 [doi]
PST - epublish
SO  - Ann Surg Open. 2021 Oct 1;2(4):e102. doi: 10.1097/AS9.0000000000000102. 
      eCollection 2021 Dec.