PMID- 37646386
OWN - NLM
STAT- MEDLINE
DCOM- 20240208
LR  - 20240311
IS  - 1546-3141 (Electronic)
IS  - 0361-803X (Linking)
VI  - 222
IP  - 1
DP  - 2024 Jan
TI  - Photon-Counting Detector CT Versus Energy-Integrating Detector CT of the Lumbar 
      Spine: Comparison of Radiation Dose and Image Quality.
PG  - e2329950
LID - 10.2214/AJR.23.29950 [doi]
AB  - BACKGROUND. Photon-counting detector (PCD) CT could be useful to help address the 
      typically high radiation doses of conventional energy-integrating detector (EID) 
      CT of the lumbar spine. OBJECTIVE. The purpose of our study was to compare PCD CT 
      and EID CT of the lumbar spine, both performed using tin filtration, in terms of 
      radiation dose and image quality. METHODS. This study included a prospective 
      sample of 39 patients (22 men, 17 women; mean age, 27.2 years) who underwent 
      investigational PCD CT of the lumbar spine as part of a separate study and a 
      retrospective sample of 39 patients (22 men, 17 women; mean age, 34.9 years) who 
      underwent clinically indicated EID CT of the lumbar spine. In both groups, all 
      examinations were performed using unenhanced technique with tin prefiltration 
      between June 2022 and January 2023. Patients were matched between groups using 
      age, sex, and BMI. A custom gaussian curve-fitting algorithm was used to 
      automatically calculate image noise, SNR, and CNR for each examination, on the 
      basis of all voxels within the image set. Three radiologists independently 
      reviewed examinations to perform a subjective visual assessment of visualization 
      of trabecular architecture, cortical bone, neuroforaminal content, paraspinal 
      muscles, and intervertebral disk, as well as overall image quality, using a 
      4-point Likert scale (1 = poor, 4 = excellent). PCD CT and EID CT examinations 
      were compared. RESULTS. Mean CTDI(vol) was 4.4 +/- 1.0 (SD) mGy for PCD CT versus 
      11.1 +/- 1.9 mGy for EID CT (p < .001). Mean size-specific dose estimate (SSDE) was 
      6.2 +/- 1.0 (SD) mGy for PCD CT versus 14.2 +/- 1.8 mGy for EID CT (p < .001). PCD CT 
      and EID CT examinations were not significantly different in terms of image noise 
      or SNR (both p > .05). PCD CT, in comparison with EID CT, showed significantly 
      higher CNR (mean +/- SD, 33.6 +/- 3.3 vs 29.3 +/- 4.1; p < .001). For all three 
      readers, the median score for overall image quality was 4 (range, 3-4) for both 
      PCD CT and EID CT. PCD CT and EID CT examinations showed no significant 
      difference in terms of any qualitative measure for any reader (all p > .05). 
      CONCLUSION. PCD CT, in comparison with EID CT, yielded significantly lower 
      radiation dose with preserved image quality. CLINICAL IMPACT. The findings 
      support expanded use of PCD CT for lumbar spine evaluation.
FAU - Marth, Adrian A
AU  - Marth AA
AD  - Swiss Center for Musculoskeletal Imaging, Balgrist Campus AG, Lengghalde 5, 
      Zurich 8008, Switzerland.
AD  - Department of Radiology, Balgrist University Hospital, University of Zurich, 
      Zurich, Switzerland.
FAU - Marcus, Roy P
AU  - Marcus RP
AD  - Department of Radiology, Balgrist University Hospital, University of Zurich, 
      Zurich, Switzerland.
FAU - Feuerriegel, Georg C
AU  - Feuerriegel GC
AD  - Department of Radiology, Balgrist University Hospital, University of Zurich, 
      Zurich, Switzerland.
FAU - Nanz, Daniel
AU  - Nanz D
AD  - Swiss Center for Musculoskeletal Imaging, Balgrist Campus AG, Lengghalde 5, 
      Zurich 8008, Switzerland.
FAU - Sutter, Reto
AU  - Sutter R
AD  - Department of Radiology, Balgrist University Hospital, University of Zurich, 
      Zurich, Switzerland.
LA  - eng
PT  - Journal Article
DEP - 20230830
PL  - United States
TA  - AJR Am J Roentgenol
JT  - AJR. American journal of roentgenology
JID - 7708173
RN  - 7440-31-5 (Tin)
SB  - IM
CIN - AJR Am J Roentgenol. 2023 Sep 13;:. PMID: 37703201
MH  - Male
MH  - Humans
MH  - Female
MH  - Adult
MH  - *Tin
MH  - Prospective Studies
MH  - Retrospective Studies
MH  - *Photons
MH  - Phantoms, Imaging
MH  - Tomography, X-Ray Computed/methods
MH  - Radiation Dosage
OTO - NOTNLM
OT  - CT
OT  - dose reduction
OT  - lumbar spine
OT  - photon-counting detector CT
OT  - spectral shaping
EDAT- 2023/08/30 12:42
MHDA- 2024/02/08 06:42
CRDT- 2023/08/30 07:43
PHST- 2024/02/08 06:42 [medline]
PHST- 2023/08/30 12:42 [pubmed]
PHST- 2023/08/30 07:43 [entrez]
AID - 10.2214/AJR.23.29950 [doi]
PST - ppublish
SO  - AJR Am J Roentgenol. 2024 Jan;222(1):e2329950. doi: 10.2214/AJR.23.29950. Epub 
      2023 Aug 30.