PMID- 37652298
OWN - NLM
STAT- MEDLINE
DCOM- 20231128
LR  - 20240205
IS  - 1535-7732 (Electronic)
IS  - 1051-0443 (Linking)
VI  - 34
IP  - 12
DP  - 2023 Dec
TI  - Safety and Effectiveness of Sclerotherapy for Nonparasitic Splenic Cysts: A 
      Systematic Review and Meta-Analysis.
PG  - 2110-2119.e1
LID - S1051-0443(23)00645-0 [pii]
LID - 10.1016/j.jvir.2023.08.033 [doi]
AB  - PURPOSE: To assess the reported safety and effectiveness of sclerotherapy for the 
      treatment of nonparasitic splenic cysts through a systematic review and 
      meta-analysis. MATERIALS AND METHODS: A systematic search of PubMed MEDLINE, 
      Embase, Web of Science, and the Cochrane Library through July 2023 was performed. 
      Studies including at least 5 patients reporting percutaneous sclerotherapy of 
      nonparasitic splenic cysts, initial and posttreatment cyst size, clinical 
      symptoms as well as adverse events (AEs), and recurrence rates were included. A 
      0-8-point scale for case reports and case series was used to assess bias. Data 
      were analyzed using random-effects meta-analysis. RESULTS: Twenty-three of 833 
      citations were selected for full-text assessment, and 7 studies were included for 
      a total of 99 patients. The methodological quality of the studies included scored 
      3-7. Composite analysis demonstrated 38% (95% CI, 23%-55%) rate of recurrence 
      after treatment with significant heterogeneity; however, when assessed for a cyst 
      size of <8 cm, recurrence dropped to 7% (95% CI, 2%-20%). Residual symptoms after 
      treatment completion were present in 17% (95% CI, 7%-33%). Intraprocedural and 
      postprocedural AE rates were 6% (95% CI, 3%-13%) and 6% (95% CI, 3%-12%) 
      respectively. CONCLUSIONS: Sclerotherapy of splenic cysts seemed to be safe, with 
      a high rate of recurrence for cysts >/=8 cm.
CI  - Copyright (c) 2023 SIR. All rights reserved.
FAU - Gasparetto, Alessandro
AU  - Gasparetto A
AD  - Department of Interventional Radiology, Hospital for Sick Children, University of 
      Toronto, Toronto, Ontario, Canada. Electronic address: 
      Alessandro.gasparetto@sickkids.ca.
FAU - Alonso, Jaime
AU  - Alonso J
AD  - Department of Interventional Radiology, Hospital for Sick Children, University of 
      Toronto, Toronto, Ontario, Canada.
FAU - Temple, Michael
AU  - Temple M
AD  - Department of Interventional Radiology, St. Jude Hospital, University of 
      Tennessee, Memphis, Tennessee.
FAU - Parra, Dimitri
AU  - Parra D
AD  - Department of Interventional Radiology, Hospital for Sick Children, University of 
      Toronto, Toronto, Ontario, Canada.
FAU - Chiramel, George
AU  - Chiramel G
AD  - Department of Interventional Radiology, Hospital for Sick Children, University of 
      Toronto, Toronto, Ontario, Canada.
FAU - Chand, Rajat
AU  - Chand R
AD  - Department of Interventional Radiology, UNC Hospitals, University of North 
      Carolina, Chapel Hill, North Carolina.
FAU - Amaral, Joao
AU  - Amaral J
AD  - Department of Interventional Radiology, Hospital for Sick Children, University of 
      Toronto, Toronto, Ontario, Canada.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20230829
PL  - United States
TA  - J Vasc Interv Radiol
JT  - Journal of vascular and interventional radiology : JVIR
JID - 9203369
SB  - IM
MH  - Humans
MH  - Sclerotherapy/adverse effects
MH  - *Cysts/diagnostic imaging/therapy
MH  - *Splenic Diseases/diagnostic imaging/therapy
EDAT- 2023/09/01 00:41
MHDA- 2023/11/28 06:42
CRDT- 2023/08/31 19:28
PHST- 2023/04/17 00:00 [received]
PHST- 2023/08/18 00:00 [revised]
PHST- 2023/08/21 00:00 [accepted]
PHST- 2023/11/28 06:42 [medline]
PHST- 2023/09/01 00:41 [pubmed]
PHST- 2023/08/31 19:28 [entrez]
AID - S1051-0443(23)00645-0 [pii]
AID - 10.1016/j.jvir.2023.08.033 [doi]
PST - ppublish
SO  - J Vasc Interv Radiol. 2023 Dec;34(12):2110-2119.e1. doi: 
      10.1016/j.jvir.2023.08.033. Epub 2023 Aug 29.