PMID- 37652514
OWN - NLM
STAT- MEDLINE
DCOM- 20231102
LR  - 20231102
IS  - 1791-7549 (Electronic)
IS  - 0258-851X (Print)
IS  - 0258-851X (Linking)
VI  - 37
IP  - 5
DP  - 2023 Sep-Oct
TI  - Acupuncture Treatment Improves Transport Stress in Microminipigs Through the 
      Acupoint in Ears.
PG  - 2100-2104
LID - 10.21873/invivo.13307 [doi]
AB  - BACKGROUND/AIM: This study aimed to investigate the effects of acupuncture 
      treatment through the ear acupoints on transport stress in experimental 
      microminipigs. MATERIALS AND METHODS: Experiment 1: Six animals were equally 
      divided into two groups (Control and Treatment). In the treatment group, before 
      transportation (6 h; vehicle and plane), short, ultrathin circular transdermal 
      needles were applied to locations corresponding to the acupoints on the apical 
      area of both ears. Peripheral blood samples were collected from the cranial vena 
      cava 2 days before and immediately after transportation. Blood stress markers, 
      biochemistry indicators, and oxidative stress levels were examined. Experiment 2 
      (follow-up study: diarrhea incidence after transportation): Diarrhea incidence 
      after transportation in the control and treatment groups was investigated. 
      RESULTS: Experiment 1: Transport stress induced an increase in blood cortisol, 
      serum amyloid A (SAA), glucose, non-esterified fatty acid, and derivatives of 
      reactive oxygen metabolites (d-ROMs) and decreased the biological antioxidant 
      potential (BAP)/d-ROMs ratio yet did not affect BAP. Acupuncture suppressed the 
      increases in SAA and d-ROMs values and the decrease in BAP/d-ROMs ratio. 
      Experiment 2: The total diarrhea incidence was 25% in the control group, whereas 
      diarrhea was not observed in the treatment group. CONCLUSION: Acupuncture 
      treatment suppresses hypothalamic-pituitary-adrenal function and, as a result, 
      reduces transport stress without affecting the suppression of the central 
      catecholaminergic system. Acupuncture treatment for transport stress can improve 
      animal welfare.
CI  - Copyright (c) 2023, International Institute of Anticancer Research (Dr. George J. 
      Delinasios), All rights reserved.
FAU - Ijiri, Moe
AU  - Ijiri M
AD  - Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
FAU - Akioka, Kohei
AU  - Akioka K
AD  - Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
FAU - Kitano, Taisuke
AU  - Kitano T
AD  - School of Veterinary Medicine, Kitasato University, Aomori, Japan.
FAU - Miura, Hiroshi
AU  - Miura H
AD  - School of Veterinary Medicine, Kitasato University, Aomori, Japan.
FAU - Ono, Hisaya K
AU  - Ono HK
AD  - School of Veterinary Medicine, Kitasato University, Aomori, Japan.
FAU - Terashima, Ryota
AU  - Terashima R
AD  - School of Veterinary Medicine, Kitasato University, Aomori, Japan.
FAU - Fujimoto, Yoshikazu
AU  - Fujimoto Y
AD  - Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
FAU - Matsuo, Tomohide
AU  - Matsuo T
AD  - Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
FAU - Yamato, Osamu
AU  - Yamato O
AD  - Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
FAU - Kawaguchi, Hiroaki
AU  - Kawaguchi H
AD  - Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan; 
      hirok@vmas.kitasato-u.ac.jp.
AD  - School of Veterinary Medicine, Kitasato University, Aomori, Japan.
LA  - eng
PT  - Journal Article
PL  - Greece
TA  - In Vivo
JT  - In vivo (Athens, Greece)
JID - 8806809
RN  - 0 (Antioxidants)
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Animals
MH  - *Acupuncture Points
MH  - Follow-Up Studies
MH  - Oxidative Stress
MH  - Antioxidants/pharmacology
MH  - *Acupuncture Therapy
MH  - Oxygen
MH  - Diarrhea
PMC - PMC10500517
OTO - NOTNLM
OT  - Acupuncture
OT  - animal welfare
OT  - swine
OT  - transport stress
COIS- No conflicts of interest exist concerning this study.
EDAT- 2023/09/01 00:42
MHDA- 2023/09/01 00:43
PMCR- 2023/09/03
CRDT- 2023/08/31 20:37
PHST- 2023/06/06 00:00 [received]
PHST- 2023/07/06 00:00 [revised]
PHST- 2023/07/07 00:00 [accepted]
PHST- 2023/09/01 00:43 [medline]
PHST- 2023/09/01 00:42 [pubmed]
PHST- 2023/08/31 20:37 [entrez]
PHST- 2023/09/03 00:00 [pmc-release]
AID - 37/5/2100 [pii]
AID - 10.21873/invivo.13307 [doi]
PST - ppublish
SO  - In Vivo. 2023 Sep-Oct;37(5):2100-2104. doi: 10.21873/invivo.13307.