PMID- 37654566
OWN - NLM
STAT- Publisher
LR  - 20230902
IS  - 1664-2392 (Print)
IS  - 1664-2392 (Electronic)
IS  - 1664-2392 (Linking)
VI  - 14
DP  - 2023
TI  - Quality of life in the course of a one-year use of an advanced hybrid closed-loop 
      system in adults with type 1 diabetes previously naive to advanced diabetes 
      technology.
PG  - 1210756
LID - 10.3389/fendo.2023.1210756 [doi]
LID - 1210756
AB  - AIM: To evaluate the effect of a one-year use of an advanced hybrid closed-loop 
      (AHCL) system on the quality of life, level of anxiety, and level of 
      self-efficacy in adults with type 1 diabetes (T1D) previously treated with 
      multiple daily injections (MDI) and naive to advanced diabetes technology. 
      METHODS: A total of 18 participants of a previously published 3-month randomized 
      trial (10 men, 8 women; age 40.9 +/- 7.6 years) who were switched directly from 
      MDI/BMG to AHCL completed 12 months of MiniMed 780Gsystem use (a 3-month 
      randomized trial followed by a 9-month follow-up phase). At month 6 of the study, 
      patients were switched from the sensor GS3 (Continuous Glucose Monitoring) 
      system, powered by Guardian Sensor 3) to GS4. Quality of life was assessed using 
      the Polish validated version of the 'QoL-Q Diabetes' questionnaire. The level of 
      anxiety was evaluated with the use of the State-Trait Anxiety Inventory (STAI). 
      Self-efficacy was assessed with the General Self-Efficacy Scale (GSES). Results 
      were obtained at baseline and at the end of the study. RESULTS: Significant 
      increase in QoL was reported in the global score (p=0.02, Cohen d=0.61) and in as 
      many as 11 out of 23 analyzed areas of life: being physically active (p=0.02, 
      Cohen d = 0.71); feeling well (p<.01, Cohen d = 0.73); feeling in control of my 
      body (p<.01, Cohen d = 0.72); looking good (p<.01, Cohen d = 1.07); working 
      (p<.01, Cohen d = 1.12); sleeping (p=0.01, Cohen d = 0.66); eating as I would 
      like (p<.01, Cohen d = 0.79); looking after or being useful to others (p= 0.02, 
      Cohen d = 0.65); being active with pets/animals (p<.01, Cohen d = 0.95); being 
      spontaneous (p=0.02, Cohen d = 0.67); and doing "normal" things (p=0.02, Cohen d 
      = 0.67). Both state (p=0.04, Cohen d = 0.56) and trait (p=0.02, Cohen d = 0.60) 
      anxiety decreased while the general self-efficacy increased (p=0.03, Cohen d = 
      0.76). No participant stopped the use of the pump. CONCLUSION: Adult patients 
      with T1D previously treated with MDI and naive to modern technologies experienced 
      significant improvement in their psychological well-being after transitioning to 
      the AHCL system after 12 months of treatment.
CI  - Copyright (c) 2023 Cyranka, Matejko, Juza, Kiec-Wilk, Cohen, Malecki and Klupa.
FAU - Cyranka, Katarzyna
AU  - Cyranka K
AD  - Department of Metabolic Diseases, Jagiellonian University Medical College, 
      Krakow, Poland.
AD  - University Hospital in Krakow, Krakow, Poland.
AD  - Department of Psychiatry, Jagiellonian University Medical College, Krakow, 
      Poland.
FAU - Matejko, Bartlomiej
AU  - Matejko B
AD  - Department of Metabolic Diseases, Jagiellonian University Medical College, 
      Krakow, Poland.
AD  - University Hospital in Krakow, Krakow, Poland.
FAU - Juza, Anna
AU  - Juza A
AD  - Clinical Provincial Hospital of Frederic Chopin No. 1 in Rzeszow, Rzeszow, 
      Poland.
AD  - College of Medical Sciences, University of Rzeszow, Rzeszow, Poland.
FAU - Kiec-Wilk, Beata
AU  - Kiec-Wilk B
AD  - Department of Metabolic Diseases, Jagiellonian University Medical College, 
      Krakow, Poland.
AD  - University Hospital in Krakow, Krakow, Poland.
FAU - Cohen, Ohad
AU  - Cohen O
AD  - Medtronic, Tolochenaz, Switzerland.
FAU - Malecki, Maciej T
AU  - Malecki MT
AD  - Department of Metabolic Diseases, Jagiellonian University Medical College, 
      Krakow, Poland.
AD  - University Hospital in Krakow, Krakow, Poland.
FAU - Klupa, Tomasz
AU  - Klupa T
AD  - Department of Metabolic Diseases, Jagiellonian University Medical College, 
      Krakow, Poland.
AD  - University Hospital in Krakow, Krakow, Poland.
LA  - eng
PT  - Journal Article
DEP - 20230815
PL  - Switzerland
TA  - Front Endocrinol (Lausanne)
JT  - Frontiers in endocrinology
JID - 101555782
SB  - IM
PMC - PMC10466125
OTO - NOTNLM
OT  - advanced hybrid closed-loop system
OT  - anxiety
OT  - diabetes type 1
OT  - quality of life
OT  - self-efficacy
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2023/09/01 06:43
MHDA- 2023/09/01 06:43
PMCR- 2023/01/01
CRDT- 2023/09/01 03:57
PHST- 2023/04/23 00:00 [received]
PHST- 2023/07/25 00:00 [accepted]
PHST- 2023/09/01 06:43 [medline]
PHST- 2023/09/01 06:43 [pubmed]
PHST- 2023/09/01 03:57 [entrez]
PHST- 2023/01/01 00:00 [pmc-release]
AID - 10.3389/fendo.2023.1210756 [doi]
PST - epublish
SO  - Front Endocrinol (Lausanne). 2023 Aug 15;14:1210756. doi: 
      10.3389/fendo.2023.1210756. eCollection 2023.