PMID- 37655618
OWN - NLM
STAT- MEDLINE
DCOM- 20230920
LR  - 20231101
IS  - 1526-4610 (Electronic)
IS  - 0017-8748 (Linking)
VI  - 63
IP  - 8
DP  - 2023 Sep
TI  - Resting-state electroencephalography microstate dynamics altered in patients with 
      migraine with and without aura-A pilot study.
PG  - 1087-1096
LID - 10.1111/head.14622 [doi]
AB  - OBJECTIVE: To evaluate electroencephalography (EEG) microstate differences 
      between patients with migraine with aura (MWA), patients with migraine without 
      aura (MWoA), and healthy controls (HC). BACKGROUND: Previous research employing 
      microstate analysis found unique microstate alterations in patients with MWoA; 
      however, it is uncertain how microstates appear in patients with MWA. METHODS: 
      This study was conducted at the Headache Clinic of the First Affiliated Hospital 
      of Xi'an Jiaotong University. In total, 30 patients with MWA, 30 with MWoA, and 
      30 HC were enrolled in this cross-sectional study. An EEG was recorded for all 
      participants under resting state. The microstate parameters of four widely 
      recognized microstate classes A-D were calculated and compared across the three 
      groups. RESULTS: The occurrence of microstate B (MsB) in the MWoA group was 
      significantly higher than in the HC (p = 0.006, Cohen's d = 0.72) and MWA 
      (p = 0.016, Cohen's d = 0.57) groups, while the contribution of MsB was 
      significantly increased in the MWoA group compared to the HC group (p = 0.016, 
      Cohen's d = 0.64). Microstate A (MsA) displayed a longer duration in the MWA 
      group compared to the MWoA group (p = 0.007, Cohen's d = 0.69). Furthermore, the 
      transition probability between MsB and microstate D was significantly increased 
      in the MWoA group compared to the HC group (p = 0.009, Cohen's d = 0.68 for B to 
      D; p = 0.007, Cohen's d = 0.71 for D to B). Finally, the occurrence and 
      contribution of MsB were positively related to headache characteristics in the 
      MWoA group but negatively in the MWA group, whereas the duration of MsA was 
      positively related to the visual analog scale in the MWA group (all p < 0.05). 
      CONCLUSIONS: Patients with MWA and MWoA have altered microstate dynamics, 
      indicating that resting-state brain network disorders may play a role in migraine 
      pathogenesis. Microstate parameters may have the potential to aid clinical 
      management, which needs to be investigated further.
CI  - (c) 2023 The Authors. Headache: The Journal of Head and Face Pain published by 
      Wiley Periodicals LLC on behalf of American Headache Society.
FAU - Lei, Xiangyu
AU  - Lei X
AD  - Department of Neurology, the First Affiliated Hospital of Xi'an Jiaotong 
      University, Xi'an, China.
FAU - Wei, Meng
AU  - Wei M
AD  - Department of Neurology, the First Affiliated Hospital of Xi'an Jiaotong 
      University, Xi'an, China.
FAU - Wang, Liang
AU  - Wang L
AD  - Department of Neurology, the First Affiliated Hospital of Xi'an Jiaotong 
      University, Xi'an, China.
FAU - Liu, Chenyu
AU  - Liu C
AD  - Department of Neurology, the First Affiliated Hospital of Xi'an Jiaotong 
      University, Xi'an, China.
FAU - Liu, Qin
AU  - Liu Q
AD  - Department of Neurology, the First Affiliated Hospital of Xi'an Jiaotong 
      University, Xi'an, China.
FAU - Wu, Xiaoyu
AU  - Wu X
AD  - Department of Neurology, the First Affiliated Hospital of Xi'an Jiaotong 
      University, Xi'an, China.
FAU - Wang, Qingfan
AU  - Wang Q
AD  - Department of Neurology, the First Affiliated Hospital of Xi'an Jiaotong 
      University, Xi'an, China.
FAU - Sun, Xinyue
AU  - Sun X
AD  - Department of Neurology, the First Affiliated Hospital of Xi'an Jiaotong 
      University, Xi'an, China.
FAU - Luo, Guogang
AU  - Luo G
AD  - Department of Neurology, the First Affiliated Hospital of Xi'an Jiaotong 
      University, Xi'an, China.
FAU - Qi, Yi
AU  - Qi Y
AD  - Department of Neurology, the First Affiliated Hospital of Xi'an Jiaotong 
      University, Xi'an, China.
LA  - eng
GR  - 2019QN-13/the First Affiliated Hospital of Xi'an Jiaotong University Foundation/
GR  - 2022JQ-987/Natural Science Foundation of Shaanxi Province/
GR  - 2021ZYTS-12/Research and Development Funds of Xian Jiaotong University First 
      Affiliated Hospital/
PT  - Comment
PT  - Journal Article
DEP - 20230901
PL  - United States
TA  - Headache
JT  - Headache
JID - 2985091R
SB  - IM
CON - J Headache Pain. 2023 Feb 20;24(1):13. PMID: 36800935
MH  - Humans
MH  - Pilot Projects
MH  - Cross-Sectional Studies
MH  - *Migraine with Aura/diagnostic imaging
MH  - *Migraine without Aura/diagnostic imaging
MH  - Headache
MH  - *Brain Diseases
MH  - Electroencephalography
MH  - *Epilepsy
OTO - NOTNLM
OT  - electroencephalography
OT  - microstate dynamics
OT  - migraine
EDAT- 2023/09/01 12:43
MHDA- 2023/09/20 06:42
CRDT- 2023/09/01 06:46
PHST- 2023/07/27 00:00 [revised]
PHST- 2023/04/04 00:00 [received]
PHST- 2023/07/28 00:00 [accepted]
PHST- 2023/09/20 06:42 [medline]
PHST- 2023/09/01 12:43 [pubmed]
PHST- 2023/09/01 06:46 [entrez]
AID - 10.1111/head.14622 [doi]
PST - ppublish
SO  - Headache. 2023 Sep;63(8):1087-1096. doi: 10.1111/head.14622. Epub 2023 Sep 1.