PMID- 37655673 OWN - NLM STAT- MEDLINE DCOM- 20231110 LR - 20231110 IS - 1600-0501 (Electronic) IS - 0905-7161 (Linking) VI - 34 IP - 11 DP - 2023 Nov TI - Evaluation of alveolar ridge preservation in sockets with buccal dehiscence defects using two types of xenogeneic biomaterials: An in vivo experimental study. PG - 1289-1298 LID - 10.1111/clr.14169 [doi] AB - OBJECTIVES: Alveolar ridge preservation (ARP) has been extensively investigated in various preclinical and clinical studies, yielding favorable results. We aim to evaluate the effects of ARP using collagenated bovine bone mineral (CBBM) alone or particulated bovine bone mineral with a non-cross-linked collagen membrane (PBBM/NCLM) in tooth extraction sockets with buccal dehiscence in an experimental dog model. MATERIALS AND METHODS: The mesial roots of three mandibular premolars (P2, P3, and P4) were extracted from six mongrel dogs 4 weeks after inducing dehiscence defects. ARP was randomly performed using two different protocols: 1) CBBM alone and 2) PBBM/NCLM. Three-dimensional (3D) volumetric, micro-computed tomography, and histological analyses were employed to determine changes over a span of 20 weeks. RESULTS: In 3D volumetric and radiographic analyses, CBBM alone demonstrated similar effectiveness to PBBM/NCLM in ARP (p > .05). However, in the PBBM/NCLM group (3.05 +/- 0.60 mm), the horizontal ridge width was well maintained 3 mm below the alveolar crest compared with the CBBM group (2.11 +/- 1.01 mm, p = .002). CONCLUSION: Although the radiographic changes in the quality and quantity of bone were not significant between the two groups, the use of PBBM/NCLM resulted in greater horizontal dimensions and more favorable maintenance of the ridge profile. CI - (c) 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. FAU - Han, Hee-Seung AU - Han HS AUID- ORCID: 0000-0002-6034-3246 AD - Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University and Seoul National University Dental Hospital, Seoul, Republic of Korea. FAU - Lee, Jung-Tae AU - Lee JT AUID- ORCID: 0000-0001-5383-3004 AD - One-Stop Specialty Center, Seoul National University, Dental Hospital, Seoul, Republic of Korea. FAU - Oh, Seunghan AU - Oh S AUID- ORCID: 0000-0002-7250-721X AD - Department of Dental Biomaterials, The Institute of Biomaterial and Implant, School of Dentistry, Wonkwang University, Iksan, Republic of Korea. FAU - Cho, Young-Dan AU - Cho YD AUID- ORCID: 0000-0002-4694-5988 AD - Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University and Seoul National University Dental Hospital, Seoul, Republic of Korea. FAU - Kim, Sungtae AU - Kim S AUID- ORCID: 0000-0001-6361-4104 AD - Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University and Seoul National University Dental Hospital, Seoul, Republic of Korea. LA - eng GR - Ministry of Health and Welfare, Republic of Korea/ GR - Ministry of Trade, Industry and Energy/ GR - National Research Foundation of Korea/ PT - Journal Article DEP - 20230901 PL - Denmark TA - Clin Oral Implants Res JT - Clinical oral implants research JID - 9105713 RN - 9007-34-5 (Collagen) RN - TRS31EO6ZN (bone meal) RN - 0 (Minerals) MH - Dogs MH - Animals MH - Cattle MH - X-Ray Microtomography MH - *Alveolar Ridge Augmentation/methods MH - Alveolar Process/diagnostic imaging/surgery/pathology MH - Tooth Socket/diagnostic imaging/surgery/pathology MH - Collagen MH - Minerals/pharmacology/therapeutic use OTO - NOTNLM OT - alveolar ridge augmentation OT - bone regeneration OT - collagen OT - tooth extraction OT - tooth socket EDAT- 2023/09/01 12:42 MHDA- 2023/11/10 06:45 CRDT- 2023/09/01 06:49 PHST- 2023/07/11 00:00 [revised] PHST- 2023/03/14 00:00 [received] PHST- 2023/08/09 00:00 [accepted] PHST- 2023/11/10 06:45 [medline] PHST- 2023/09/01 12:42 [pubmed] PHST- 2023/09/01 06:49 [entrez] AID - 10.1111/clr.14169 [doi] PST - ppublish SO - Clin Oral Implants Res. 2023 Nov;34(11):1289-1298. doi: 10.1111/clr.14169. Epub 2023 Sep 1.