PMID- 37666953
OWN - NLM
STAT- MEDLINE
DCOM- 20230906
LR  - 20231123
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 13
IP  - 1
DP  - 2023 Sep 4
TI  - Identification and classification of ATS in oral fluid based on Ag nanoassemblies 
      on Si surface doped with Au nanobipyramids.
PG  - 14526
LID - 10.1038/s41598-023-41860-5 [doi]
LID - 14526
AB  - Herein, a novel Ag NP substrate doped with Au nanobipyramids was designed and 
      fabricated via a convenient procedure of galvanic reaction for the identification 
      and classification of amphetamine-type stimulants (ATS) in oral fluids in 
      combination with surface enhanced Raman scattering (SERS). The substrate was 
      shown to have a three-dimensional nanostructure, high SERS activity, and good 
      stability. In combination with SERS, the Ag NP substrate doped with Au 
      nanobipyramids was able to detect ultra-low traces of ATS, including amphetamine, 
      methylamphetamine (MA), 3,4-methylenedioxyamphetamine (MDA), and 
      3,4-methylenedioxymethylamphetamine (MDMA) in oral fluid with limit of detection 
      (LOD) and limit of determination quantitation (LOQ) as low as 10(-9) mg/mL, which 
      is much better than the current spectroscopic techniques. The equations between 
      concentration and peaks intensity for quantitative analysis displied good 
      doublelogarithmic linear relations and reliability figures of merit at nanogram 
      concentration level in compartion with GC-MS method. The approach can be broadly 
      applied to the ultra-low trace detection of ATS in oral fluid and would be 
      particularly useful for the analyses of nitrogenous organic compounds.
CI  - (c) 2023. Springer Nature Limited.
FAU - Cui, Sheng-Feng
AU  - Cui SF
AD  - Center for Traffic Evidence Technology, Zhengzhou Key Laboratory of Criminal 
      Science and Technology, Department of Criminal Science and Technology, Railway 
      Police College, Zhengzhou, 450053, People's Republic of China. 
      cuishengfeng@rpc.edu.cn.
FAU - Yang, Hai-Long
AU  - Yang HL
AD  - Center for Traffic Evidence Technology, Zhengzhou Key Laboratory of Criminal 
      Science and Technology, Department of Criminal Science and Technology, Railway 
      Police College, Zhengzhou, 450053, People's Republic of China.
FAU - Huang, Xin
AU  - Huang X
AD  - Center for Traffic Evidence Technology, Zhengzhou Key Laboratory of Criminal 
      Science and Technology, Department of Criminal Science and Technology, Railway 
      Police College, Zhengzhou, 450053, People's Republic of China.
FAU - Wan, Jing-Wei
AU  - Wan JW
AD  - Center for Traffic Evidence Technology, Zhengzhou Key Laboratory of Criminal 
      Science and Technology, Department of Criminal Science and Technology, Railway 
      Police College, Zhengzhou, 450053, People's Republic of China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230904
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
RN  - CK833KGX7E (Amphetamine)
RN  - 0 (Central Nervous System Stimulants)
RN  - 44RAL3456C (Methamphetamine)
RN  - 4764-17-4 (3,4-Methylenedioxyamphetamine)
RN  - 0 (Nitrogen Compounds)
SB  - IM
MH  - Amphetamine
MH  - Reproducibility of Results
MH  - *Central Nervous System Stimulants
MH  - *Methamphetamine
MH  - *3,4-Methylenedioxyamphetamine
MH  - Nitrogen Compounds
PMC - PMC10477168
COIS- The authors declare no competing interests.
EDAT- 2023/09/05 00:42
MHDA- 2023/09/06 06:42
PMCR- 2023/09/04
CRDT- 2023/09/04 23:29
PHST- 2023/07/09 00:00 [received]
PHST- 2023/09/01 00:00 [accepted]
PHST- 2023/09/06 06:42 [medline]
PHST- 2023/09/05 00:42 [pubmed]
PHST- 2023/09/04 23:29 [entrez]
PHST- 2023/09/04 00:00 [pmc-release]
AID - 10.1038/s41598-023-41860-5 [pii]
AID - 41860 [pii]
AID - 10.1038/s41598-023-41860-5 [doi]
PST - epublish
SO  - Sci Rep. 2023 Sep 4;13(1):14526. doi: 10.1038/s41598-023-41860-5.