PMID- 37670851
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230907
IS  - 1178-7007 (Print)
IS  - 1178-7007 (Electronic)
IS  - 1178-7007 (Linking)
VI  - 16
DP  - 2023
TI  - The Relationship Between Non-HDL-C /HDL-C Ratio (NHHR) and Vitamin D in Type 2 
      Diabetes Mellitus.
PG  - 2661-2673
LID - 10.2147/DMSO.S414673 [doi]
AB  - PURPOSE: The objective of this research was to examine the relationship between 
      non-HDL cholesterol/HDL cholesterol ratio (NHHR) and vitamin D in type 2 diabetes 
      mellitus (T2DM). PATIENTS AND METHODS: This study enrolled 617 T2DM participants. 
      Participants were separated into two groups: no vitamin D deficiency and vitamin 
      D deficiency. Participants were split into two categories: individuals who had a 
      high NHHR and those with a low NHHR, with the median NHHR serving as the cut-off. 
      Eventually, the study participants were classified into two groups by gender, 
      which were further classified into vitamin D deficient and non-vitamin D 
      deficient groups. RESULTS: NHHR values were substantially greater in vitamin D 
      deficient group than in the non-deficient group in both male and female T2DM 
      patients (P<0.05). The high NHHR group displayed substantially lower vitamin D 
      levels than the low NHHR group [16.21 (12.55,21.35) vs 19.05 (14.59,24.07), 
      P<0.001]. NHHR was discovered to be negatively and independently associated with 
      vitamin D levels, and there was no sex difference. CONCLUSION: For the first 
      time, our research revealed a negative relationship between NHHR and vitamin D in 
      patients with T2DM.
CI  - (c) 2023 Zhen et al.
FAU - Zhen, Ruoxi
AU  - Zhen R
AUID- ORCID: 0009-0004-4517-8571
AD  - Graduate School, Hebei Medical University, Shijiazhuang, Hebei, People's Republic 
      of China.
AD  - Department of Endocrinology, Hebei General Hospital, Shijiazhuang, Hebei, 
      People's Republic of China.
FAU - Ban, Jiangli
AU  - Ban J
AD  - Department of Endocrinology, Hebei General Hospital, Shijiazhuang, Hebei, 
      People's Republic of China.
AD  - Graduate School, Hebei North University, Zhangjiakou, People's Republic of China.
FAU - Jia, Zhuoya
AU  - Jia Z
AD  - Graduate School, Hebei Medical University, Shijiazhuang, Hebei, People's Republic 
      of China.
AD  - Department of Endocrinology, Hebei General Hospital, Shijiazhuang, Hebei, 
      People's Republic of China.
FAU - Liu, Yanhui
AU  - Liu Y
AD  - Department of Endocrinology, Hebei General Hospital, Shijiazhuang, Hebei, 
      People's Republic of China.
AD  - Graduate School, Hebei North University, Zhangjiakou, People's Republic of China.
FAU - Li, Zelin
AU  - Li Z
AD  - Graduate School, Hebei Medical University, Shijiazhuang, Hebei, People's Republic 
      of China.
AD  - Department of Endocrinology, Hebei General Hospital, Shijiazhuang, Hebei, 
      People's Republic of China.
FAU - Chen, Shuchun
AU  - Chen S
AD  - Graduate School, Hebei Medical University, Shijiazhuang, Hebei, People's Republic 
      of China.
AD  - Department of Endocrinology, Hebei General Hospital, Shijiazhuang, Hebei, 
      People's Republic of China.
AD  - Hebei Key Laboratory of Metabolic Diseases, Shijiazhuang, Hebei, People's 
      Republic of China.
LA  - eng
PT  - Journal Article
DEP - 20230831
PL  - New Zealand
TA  - Diabetes Metab Syndr Obes
JT  - Diabetes, metabolic syndrome and obesity : targets and therapy
JID - 101515585
PMC - PMC10476667
OTO - NOTNLM
OT  - diabetes
OT  - lipid ratio
OT  - non-HDL-C /HDL-C
OT  - type 2 diabetes
OT  - vitamin D
COIS- The authors report no conflicts of interest in this work.
EDAT- 2023/09/06 06:42
MHDA- 2023/09/06 06:43
PMCR- 2023/08/31
CRDT- 2023/09/06 03:46
PHST- 2023/03/31 00:00 [received]
PHST- 2023/08/19 00:00 [accepted]
PHST- 2023/09/06 06:43 [medline]
PHST- 2023/09/06 06:42 [pubmed]
PHST- 2023/09/06 03:46 [entrez]
PHST- 2023/08/31 00:00 [pmc-release]
AID - 414673 [pii]
AID - 10.2147/DMSO.S414673 [doi]
PST - epublish
SO  - Diabetes Metab Syndr Obes. 2023 Aug 31;16:2661-2673. doi: 10.2147/DMSO.S414673. 
      eCollection 2023.