PMID- 37672606 OWN - NLM STAT- MEDLINE DCOM- 20240320 LR - 20240320 IS - 2768-3613 (Electronic) IS - 2768-3605 (Linking) VI - 30 IP - 3 DP - 2024 Mar TI - Effects of qigong Training on Muscle Strengths, Flexibility, Cardiopulmonary Fitness, and Antioxidant/Oxidant Responses in Sedentary Middle-Aged and Elderly Type 2 Diabetes Mellitus Women: A Quasi-Experimental Design, Placebo-Controlled Study. PG - 288-296 LID - 10.1089/jicm.2023.0180 [doi] AB - Background: Qigong exercise training has been suggested to elicit beneficial effects on physical functioning, reduction of oxidative stress, and improved antioxidant capacity in women. However, regular exercise training may support the development of antioxidant defense mechanisms and beneficially modulate oxidant/antioxidant responses. Objective: To evaluate the effects of an 8-week qigong exercise training on exercise performance and oxidative stress responses in sedentary middle-aged and elderly women suffering from type 2 diabetic mellitus (T2DM). Method/design: Quasi-experimental design, placebo-controlled study. Setting: The Department of Physical Therapy, Faculty of Allied Health Science, Burapha University, Thailand. Participants: Thirty-six sedentary middle-aged and elderly women with T2DM. Intervention: Participants were allocated to qigong exercise (n = 20) or to the control group (CG, n = 20). Primary outcome measures: Muscle strengths, flexibility, VO(2) max predicted, and walking intensity derived from the 6-minute walk test. Secondary outcome measures: Fasting plasma glucose, antioxidant/oxidant stress parameters, and body composition. Results: Leg strength and trunk flexibility were improved after qigong training and changes were significantly different compared with the CG (all p < 0.05). VO(2) max predicted, 6-min walking distance, and walking intensity were all increased (p < 0.05), and oxidative stress markers were diminished after qigong training (p < 0.05). The antioxidant/oxidant balance was improved after qigong training (p < 0.05). Conclusion: The presented findings indicate that 8 weeks of qigong training significantly improved leg strength and trunk flexibility in middle-aged and elderly women with T2DM, partly associated with a more favorable antioxidant/oxidant balance. These effects may beneficially impact on health in this specific population. Clinical Trial Number: TCTR20221003001. FAU - Klarod, Kultida AU - Klarod K AUID- ORCID: 0000-0002-2310-7551 AD - Department of Physical Therapy, Faculty of Allied Health Sciences, Burapha University, Chonburi, Thailand. FAU - Singsanan, Sanita AU - Singsanan S AD - Department of Medical Technology, Faculty of Allied Health Sciences, Burapha University, Chonburi, Thailand. FAU - Luangpon, Nongnuch AU - Luangpon N AD - Department of Physical Therapy, Faculty of Allied Health Sciences, Burapha University, Chonburi, Thailand. FAU - Kiatkulanusorn, Sirirat AU - Kiatkulanusorn S AD - Department of Physical Therapy, Faculty of Allied Health Sciences, Burapha University, Chonburi, Thailand. FAU - Boonsiri, Patcharee AU - Boonsiri P AD - Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. FAU - Burtscher, Martin AU - Burtscher M AD - Medical Section, Department of Sport Science, Faculty of Psychology and Sport Science, University of Innsbruck, Innsbruck, Austria. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20230906 PL - United States TA - J Integr Complement Med JT - Journal of integrative and complementary medicine JID - 9918283075806676 RN - 0 (Antioxidants) RN - 0 (Oxidants) SB - IM MH - Aged MH - Middle Aged MH - Humans MH - Female MH - Antioxidants MH - *Diabetes Mellitus, Type 2/therapy MH - Oxidants MH - *Qigong MH - Exercise MH - Muscle Strength/physiology MH - Double-Blind Method OTO - NOTNLM OT - aerobic capacity OT - antioxidant/oxidant balance OT - exercise performance OT - metabolic changes OT - mind/body exercise EDAT- 2023/09/06 18:41 MHDA- 2024/03/20 06:45 CRDT- 2023/09/06 14:13 PHST- 2024/03/20 06:45 [medline] PHST- 2023/09/06 18:41 [pubmed] PHST- 2023/09/06 14:13 [entrez] AID - 10.1089/jicm.2023.0180 [doi] PST - ppublish SO - J Integr Complement Med. 2024 Mar;30(3):288-296. doi: 10.1089/jicm.2023.0180. Epub 2023 Sep 6.