PMID- 37688649 OWN - NLM STAT- MEDLINE DCOM- 20231106 LR - 20231112 IS - 0942-0940 (Electronic) IS - 0001-6268 (Linking) VI - 165 IP - 11 DP - 2023 Nov TI - Effect of baseline veterans RAND-12 physical composite score on postoperative patient-reported outcome measures following lateral lumbar interbody fusion. PG - 3531-3537 LID - 10.1007/s00701-023-05763-8 [doi] AB - PURPOSE: To determine the prognostic value of preoperative Veterans RAND-12 (VR-12) Physical Composite Score (PCS) scores on postoperative clinical outcomes in patients undergoing lateral lumbar interbody fusion (LLIF). METHODS: LLIF patients were separated into 2 cohorts based on preoperative VR-12 PCS scores: VR-12 PCS < 30 (lesser physical function) and VR-12 PCS >/= 30 (greater physical function). Patient-reported outcome measures (PROMs) of VR-12 PCS, VR-12 Mental Composite Score (MCS), Short Form-12 (SF-12) PCS, SF-12 MCS, Patient-Reported Outcomes Measurement Information System Physical Function (PROMIS-PF), Patient Health Questionnaire-9 (PHQ-9), Visual Analog Scale (VAS) Back Pain (VAS-BP), VAS Leg Pain (VAS-LP), and Oswestry Disability Index (ODI) were collected at preoperative and up to 2-year postoperative time points. Mean postoperative follow-up time was 16.69 +/- 8.53 months. Minimum clinically important difference (MCID) achievement was determined by comparing ∆PROM to previously established thresholds. RESULTS: Seventy-eight patients were included, with 38 patients with lesser preoperative physical function scores. Patients with lesser physical function reported significantly inferior preoperative PROM scores in all domains, except for SF-12 MCS and VAS-LP. At the 6-week postoperative time point, patients with lesser physical function reported significantly inferior VR-12 PCS, VR-12 MCS, SF-12 PCS, PROMIS-PF, and PHQ-9. At the final postoperative time point, patients with lesser physical function reported significantly inferior VR-12 PCS, VR-12 MCS, PROMIS-PF, PHQ-9, and ODI. Magnitude of 6-week postoperative improvement was significantly higher in the lesser physical function cohort for VR-12 PCS. CONCLUSION: Patients undergoing LLIF with worse baseline VR-12 PCS scores reported inferior postoperative physical function, mental health, and disability outcomes. At the final postoperative follow-up, magnitude of postoperative improvement and MCID achievement did not significantly differ. Baseline VR-12 PCS scores may indicate inferior postoperative clinical outcomes in physical function, mental health, and disability in patients undergoing LLIF; however, baseline VR-12 PCS does not limit the magnitude of postoperative improvement. CI - (c) 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature. FAU - Oyetayo, Omolabake O AU - Oyetayo OO AD - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612, USA. FAU - Nie, James W AU - Nie JW AD - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612, USA. FAU - Hartman, Timothy J AU - Hartman TJ AD - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612, USA. FAU - MacGregor, Keith R AU - MacGregor KR AD - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612, USA. FAU - Zheng, Eileen AU - Zheng E AD - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612, USA. FAU - Anwar, Fatima N AU - Anwar FN AD - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612, USA. FAU - Roca, Andrea M AU - Roca AM AD - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612, USA. FAU - Federico, Vincent P AU - Federico VP AD - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612, USA. FAU - Massel, Dustin H AU - Massel DH AD - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612, USA. FAU - Lopez, Gregory D AU - Lopez GD AD - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612, USA. FAU - Sayari, Arash J AU - Sayari AJ AD - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612, USA. FAU - Singh, Kern AU - Singh K AUID- ORCID: 0000-0002-6118-7273 AD - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612, USA. kern.singh@rushortho.com. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20230909 PL - Austria TA - Acta Neurochir (Wien) JT - Acta neurochirurgica JID - 0151000 SB - IM MH - Humans MH - Treatment Outcome MH - *Veterans MH - Prognosis MH - Back Pain/surgery MH - *Spinal Fusion MH - Patient Reported Outcome Measures MH - Lumbar Vertebrae/surgery MH - Retrospective Studies OTO - NOTNLM OT - Lateral lumbar interbody fusion OT - Patient-reported outcome measures OT - Physical function OT - Veterans RAND-12 EDAT- 2023/09/09 21:42 MHDA- 2023/11/06 06:42 CRDT- 2023/09/09 11:05 PHST- 2023/05/10 00:00 [received] PHST- 2023/08/07 00:00 [accepted] PHST- 2023/11/06 06:42 [medline] PHST- 2023/09/09 21:42 [pubmed] PHST- 2023/09/09 11:05 [entrez] AID - 10.1007/s00701-023-05763-8 [pii] AID - 10.1007/s00701-023-05763-8 [doi] PST - ppublish SO - Acta Neurochir (Wien). 2023 Nov;165(11):3531-3537. doi: 10.1007/s00701-023-05763-8. Epub 2023 Sep 9.