PMID- 37690961 OWN - NLM STAT- MEDLINE DCOM- 20231002 LR - 20231003 IS - 1471-4981 (Electronic) IS - 1471-4906 (Linking) VI - 44 IP - 10 DP - 2023 Oct TI - HLA alleles: important pieces to the COVID-19 puzzle. PG - 754-756 LID - S1471-4906(23)00179-5 [pii] LID - 10.1016/j.it.2023.08.011 [doi] AB - Research on human leukocyte antigen (HLA) molecules in coronavirus disease 2019 (COVID-19) raised high expectations but has yielded limited results. Augusto et al.'s recent study in Nature unveils a strong association of HLA-B*15:01 with asymptomatic COVID-19, representing an important contribution to genetics in COVID-19. CI - Copyright (c) 2023 Elsevier Ltd. All rights reserved. FAU - Castro-Santos, Patricia AU - Castro-Santos P AD - Fundacion Publica Galega de Medicina Xenomica (SERGAS). Centro Nacional de Genotipado. Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain; Faculty of Health Sciences, Universidad Autonoma de Chile, Talca, Chile. FAU - Carracedo, Angel AU - Carracedo A AD - Fundacion Publica Galega de Medicina Xenomica (SERGAS). Centro Nacional de Genotipado. Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain; Grupo de Medicina Xenomica- CIMUS- Universidade de Santiago de Compostela, Santiago de Compostela, Spain; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain. FAU - Diaz-Pena, Roberto AU - Diaz-Pena R AD - Fundacion Publica Galega de Medicina Xenomica (SERGAS). Centro Nacional de Genotipado. Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain; Faculty of Health Sciences, Universidad Autonoma de Chile, Talca, Chile. Electronic address: roberto.diaz.pena@sergas.es. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20230909 PL - England TA - Trends Immunol JT - Trends in immunology JID - 100966032 RN - 0 (Histocompatibility Antigens Class I) RN - 0 (HLA Antigens) RN - 0 (HLA-B Antigens) SB - IM MH - Humans MH - *COVID-19/genetics MH - Alleles MH - Histocompatibility Antigens Class I/genetics MH - HLA Antigens/genetics MH - HLA-B Antigens/genetics COIS- Declaration of interests None declared by authors. EDAT- 2023/09/11 00:42 MHDA- 2023/10/02 06:42 CRDT- 2023/09/10 22:02 PHST- 2023/08/16 00:00 [received] PHST- 2023/08/31 00:00 [accepted] PHST- 2023/10/02 06:42 [medline] PHST- 2023/09/11 00:42 [pubmed] PHST- 2023/09/10 22:02 [entrez] AID - S1471-4906(23)00179-5 [pii] AID - 10.1016/j.it.2023.08.011 [doi] PST - ppublish SO - Trends Immunol. 2023 Oct;44(10):754-756. doi: 10.1016/j.it.2023.08.011. Epub 2023 Sep 9.