PMID- 37692789
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230913
IS  - 2296-858X (Print)
IS  - 2296-858X (Electronic)
IS  - 2296-858X (Linking)
VI  - 10
DP  - 2023
TI  - Is acupuncture safe in the ICU? A systematic review and meta-analysis.
PG  - 1190635
LID - 10.3389/fmed.2023.1190635 [doi]
LID - 1190635
AB  - BACKGROUND AND PURPOSE: The safety of interventions for critically ill patients 
      is a crucial issue. In recent years, several studies have treated critically ill 
      patients with acupuncture. However, the safety of acupuncture in this setting 
      remains to be systematically measured. METHODS: In May 2022, the electronic 
      databases of PubMed and the Cochrane Library were searched for studies comparing 
      acupuncture interventions to control interventions in critically ill patients. 
      Study outcomes examined the incidence of severe adverse events (AEs), minor AEs, 
      adverse reactions, ICU stays, and 28-day mortality. RESULTS: A total of 31 
      articles were analyzed, and no serious AEs related to acupuncture treatment were 
      identified. No significant differences were found between the groups in the 
      meta-analysis of minor AEs (risk ratio [RR] 5.69 [0.34, 96.60], P = 0.23, I(2) = 
      76%). A reduced risk in the incidence of adverse reactions following acupuncture 
      intervention was evidenced (RR 0.33 [0.22, 0.50], P = 0.00001, I(2) = 44%). The 
      patients in the acupuncture arm spent significantly less time in the intensive 
      care unit (ICU) (Mean difference -1.45 [-11.94, -10.97], P = 0.00001, I(2) = 56%) 
      and also exhibited lower 28-day mortality rates (odds ratio 0.61 [0.48, 0.78], P 
      = 0.0001, I(2) = 0%). CONCLUSION: There is no evidence to indicate a higher risk 
      of severe or minor AEs in patients who receive acupuncture. Acupuncture 
      demonstrated favorable results in both ICU stay and 28-day mortality 
      measurements, in addition to presenting with fewer adverse reactions compared to 
      routine ICU care. However, the low certainty of the evidence resulting from a 
      high risk of bias in the included studies merits substantial consideration, and 
      further research is still warranted. SYSTEMATIC REVIEW REGISTRATION: 
      https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=142131, 
      identifier: CRD42020142131.
CI  - Copyright (c) 2023 Ben-Arie, Lottering, Chen, Ho, Lee, Inprasit and Kao.
FAU - Ben-Arie, Eyal
AU  - Ben-Arie E
AD  - Graduate School of Acupuncture Science, China Medical University, Taichung, 
      Taiwan.
FAU - Lottering, Bernice Jeanne
AU  - Lottering BJ
AD  - Graduate School of Acupuncture Science, China Medical University, Taichung, 
      Taiwan.
FAU - Chen, Fang-Pey
AU  - Chen FP
AD  - Institute of Traditional Medicine, School of Medicine, National Yang Ming Chiao 
      Tung University, Taipei, Taiwan.
FAU - Ho, Wen-Chao
AU  - Ho WC
AD  - Department of Public Health, China Medical University, Taichung, Taiwan.
FAU - Lee, Yu-Chen
AU  - Lee YC
AD  - Graduate School of Acupuncture Science, China Medical University, Taichung, 
      Taiwan.
AD  - Department of Acupuncture, China Medical University Hospital, Taichung, Taiwan.
AD  - Chinese Medicine Research Center, China Medical University, Taichung, Taiwan.
FAU - Inprasit, Chanya
AU  - Inprasit C
AD  - Suphanburi Campus Establishment Project, Kasetsart University, Suphan Buri, 
      Thailand.
FAU - Kao, Pei-Yu
AU  - Kao PY
AD  - Institute of Traditional Medicine, School of Medicine, National Yang Ming Chiao 
      Tung University, Taipei, Taiwan.
AD  - Surgical Intensive Care Unit, China Medical University Hospital, Taichung, 
      Taiwan.
AD  - Division of Thoracic Surgery, Department of Surgery, China Medical University 
      Hospital, Taichung, Taiwan.
LA  - eng
PT  - Journal Article
DEP - 20230824
PL  - Switzerland
TA  - Front Med (Lausanne)
JT  - Frontiers in medicine
JID - 101648047
PMC - PMC10484589
OTO - NOTNLM
OT  - acupuncture
OT  - adverse effects
OT  - adverse events
OT  - intensive care unit
OT  - safety
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2023/09/11 06:43
MHDA- 2023/09/11 06:44
PMCR- 2023/08/24
CRDT- 2023/09/11 04:42
PHST- 2023/03/22 00:00 [received]
PHST- 2023/07/28 00:00 [accepted]
PHST- 2023/09/11 06:44 [medline]
PHST- 2023/09/11 06:43 [pubmed]
PHST- 2023/09/11 04:42 [entrez]
PHST- 2023/08/24 00:00 [pmc-release]
AID - 10.3389/fmed.2023.1190635 [doi]
PST - epublish
SO  - Front Med (Lausanne). 2023 Aug 24;10:1190635. doi: 10.3389/fmed.2023.1190635. 
      eCollection 2023.