PMID- 37694566
OWN - NLM
STAT- MEDLINE
DCOM- 20240112
LR  - 20240306
IS  - 1475-2662 (Electronic)
IS  - 0007-1145 (Linking)
VI  - 131
IP  - 3
DP  - 2024 Feb 14
TI  - Association of dietary and lifestyle inflammation score with type 2 diabetes 
      mellitus and cardiometabolic risk factors in Iranian adults: Sabzevar Persian 
      Cohort Study.
PG  - 521-530
LID - 10.1017/S0007114523001903 [doi]
AB  - Systemic inflammation may contribute to the initiation and progression of type 2 
      diabetes mellitus (T2DM) through diet and lifestyle. We examined the association 
      of dietary inflammation score (DIS), lifestyle inflammation score (LIS) and 
      dietary and lifestyle inflammation score (DLIS) with T2DM and cardiometabolic 
      risk factors among Iranian adults. In this study, we identified and recruited 619 
      patients with T2DM and 2113 without T2DM from 35 to 75 years old men and women in 
      the baseline phase of the Sabzevar Persian Cohort Study. Using a validated 
      115-item semi-quantitative FFQ, we calculated a 19-component DIS and a 
      3-component LIS weighted by circulating inflammation biomarkers. The DIS, LIS and 
      DLIS associations with diabetes were assessed by multivariable logistic 
      regression analysis. The average age of the participants was 48.29 (sd 8.53) 
      (without T2DM: 47.66 (sd 8.42); with T2DM: 50.44 (sd 8.57)). Individuals in the 
      highest compared with the lowest tertiles of DLIS (OR: 3.40; 95 % CI 2.65, 4.35; 
      P(trend) < 0.001), DIS (OR: 3.41; 95 % CI 2.66, 4.38; P(trend) < 0.001) and LIS 
      (OR: 1.15; 95 % CI 0.90, 1.46; P(trend) = 0.521) had an increased risk of T2DM. 
      For those in the highest relative to the lowest joint DIS and LIS tertiles, the 
      results were OR: 3.37; 95 % CI 2.13, 5.32; P(interaction) < 0.001. No significant 
      associations were found between DLIS and cardiometabolic risk factors, including 
      blood pressure, liver enzymes and glycaemic and lipid profiles, except for waist 
      circumference (P < 0.001) and waist-to-hip ratio (P = 0.010). A higher DIS and 
      DLIS score was associated with a higher risk of T2DM, while the LIS score was not 
      associated with T2DM risk.
FAU - Bakhshimoghaddam, Farnush
AU  - Bakhshimoghaddam F
AD  - Nutrition and Metabolic Diseases Research Center, Clinical Sciences Research 
      Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
AD  - Department of Nutrition, School of Allied Medical Sciences, Ahvaz Jundishapur 
      University of Medical Sciences, Ahvaz, Iran.
FAU - Jafarirad, Sima
AU  - Jafarirad S
AUID- ORCID: 0000-0002-3161-5329
AD  - Nutrition and Metabolic Diseases Research Center, Clinical Sciences Research 
      Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
AD  - Department of Nutrition, School of Allied Medical Sciences, Ahvaz Jundishapur 
      University of Medical Sciences, Ahvaz, Iran.
FAU - Maraghi, Elham
AU  - Maraghi E
AUID- ORCID: 0000-0003-3556-8838
AD  - Department of Biostatistics and Epidemiology, Faculty of Public Health, Ahvaz 
      Jundishapur University of Medical Sciences, Ahvaz, Iran.
FAU - Ghorat, Fereshteh
AU  - Ghorat F
AUID- ORCID: 0000-0002-7620-2544
AD  - Non-Communicable Diseases Research Center, Sabzevar University of Medical 
      Sciences, Sabzevar, Iran.
LA  - eng
PT  - Journal Article
DEP - 20230911
PL  - England
TA  - Br J Nutr
JT  - The British journal of nutrition
JID - 0372547
SB  - IM
MH  - Male
MH  - Adult
MH  - Humans
MH  - Female
MH  - Middle Aged
MH  - Aged
MH  - *Diabetes Mellitus, Type 2
MH  - Iran/epidemiology
MH  - Cardiometabolic Risk Factors
MH  - Cohort Studies
MH  - Diet/adverse effects
MH  - Inflammation
MH  - Life Style
MH  - Risk Factors
OTO - NOTNLM
OT  - Diabetes
OT  - Diet
OT  - Inflammation
OT  - Lifestyle
EDAT- 2023/09/11 12:43
MHDA- 2024/01/12 06:42
CRDT- 2023/09/11 06:40
PHST- 2024/01/12 06:42 [medline]
PHST- 2023/09/11 12:43 [pubmed]
PHST- 2023/09/11 06:40 [entrez]
AID - S0007114523001903 [pii]
AID - 10.1017/S0007114523001903 [doi]
PST - ppublish
SO  - Br J Nutr. 2024 Feb 14;131(3):521-530. doi: 10.1017/S0007114523001903. Epub 2023 
      Sep 11.