PMID- 37697687
OWN - NLM
STAT- MEDLINE
DCOM- 20240104
LR  - 20240106
IS  - 1744-9987 (Electronic)
IS  - 1744-9979 (Linking)
VI  - 28
IP  - 1
DP  - 2024 Feb
TI  - The addition of Cytosorb in patients on VA-ECMO improves urinary output and ICU 
      survival.
PG  - 103-111
LID - 10.1111/1744-9987.14064 [doi]
AB  - INTRODUCTION: The aim of this study was to analyze the efficiency of CytoSorb 
      adsorber in patients presenting with cardiogenic shock and treated with 
      venoarterial extracorporeal membrane oxygenation (VA-ECMO). METHODS: Sixteen 
      patients put on VA ECMO due to cardiogenic shock were included, stratified 
      according to the use of Cytosorb adsorber in the first 24 h and compared across 
      different clinical outcomes. RESULTS: Significantly lower vasopressor doses were 
      required among patients treated with Cytosorb at the initiation and before 
      weaning from ECMO. Furthermore, these patients showed significantly higher urine 
      output before weaning and lower lactate levels during the extracorporeal support. 
      Finally, the mortality rate was lower among the Cytosorb therapy group (22.2% vs 
      57.1%). CONCLUSION: While a decrease in vasopressor doses was already associated 
      with CytoSorb use, this is the first study showing an increase in urinary output 
      and a trend towards better survival among patients on VA ECMO treated with 
      CytoSorb.
CI  - (c) 2023 International Society for Apheresis and Japanese Society for Apheresis.
FAU - Lovric, Daniel
AU  - Lovric D
AUID- ORCID: 0000-0002-5052-6559
AD  - Cardiology Clinic, University Hospital Center Zagreb, Zagreb, Croatia.
FAU - Pasalic, Marijan
AU  - Pasalic M
AUID- ORCID: 0000-0002-3197-2190
AD  - Cardiology Clinic, University Hospital Center Zagreb, Zagreb, Croatia.
FAU - Krizanac, Stefan
AU  - Krizanac S
AUID- ORCID: 0000-0003-1170-1155
AD  - Franziskus Spital, Wien, Austria.
FAU - Kovacic, Karla
AU  - Kovacic K
AUID- ORCID: 0000-0002-9695-9704
AD  - Emergency Medicine Institute of Koprivnica-Krizevci County, Koprivnica, Croatia.
FAU - Skoric, Bosko
AU  - Skoric B
AUID- ORCID: 0000-0001-5979-2346
AD  - Cardiology Clinic, University Hospital Center Zagreb, Zagreb, Croatia.
FAU - Jurin, Hrvoje
AU  - Jurin H
AUID- ORCID: 0000-0002-2599-553X
AD  - Cardiology Clinic, University Hospital Center Zagreb, Zagreb, Croatia.
FAU - Milicic, Davor
AU  - Milicic D
AUID- ORCID: 0000-0001-9101-1570
AD  - Cardiology Clinic, University Hospital Center Zagreb, Zagreb, Croatia.
FAU - Premuzic, Vedran
AU  - Premuzic V
AUID- ORCID: 0000-0001-6264-6809
AD  - Department of Nephrology, Hypertension, Dialysis and Transplantation, University 
      Hospital Center Zagreb, Zagreb, Croatia.
LA  - eng
PT  - Journal Article
DEP - 20230911
PL  - Australia
TA  - Ther Apher Dial
JT  - Therapeutic apheresis and dialysis : official peer-reviewed journal of the 
      International Society for Apheresis, the Japanese Society for Apheresis, the 
      Japanese Society for Dialysis Therapy
JID - 101181252
SB  - IM
MH  - Humans
MH  - *Shock, Cardiogenic/therapy
MH  - *Extracorporeal Membrane Oxygenation
MH  - Hospital Mortality
MH  - Intensive Care Units
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Cytosorb
OT  - hemoperfusion
OT  - survival
OT  - venoarterial ECMO
EDAT- 2023/09/12 06:41
MHDA- 2024/01/04 11:43
CRDT- 2023/09/12 02:23
PHST- 2023/03/18 00:00 [revised]
PHST- 2022/07/31 00:00 [received]
PHST- 2023/09/01 00:00 [accepted]
PHST- 2024/01/04 11:43 [medline]
PHST- 2023/09/12 06:41 [pubmed]
PHST- 2023/09/12 02:23 [entrez]
AID - 10.1111/1744-9987.14064 [doi]
PST - ppublish
SO  - Ther Apher Dial. 2024 Feb;28(1):103-111. doi: 10.1111/1744-9987.14064. Epub 2023 
      Sep 11.