PMID- 37703829 OWN - NLM STAT- MEDLINE DCOM- 20230915 LR - 20230918 IS - 1097-4180 (Electronic) IS - 1074-7613 (Linking) VI - 56 IP - 9 DP - 2023 Sep 12 TI - Making good of a tricky start: How IgE and mast cells manage a protective sway in food allergy. PG - 1988-1990 LID - S1074-7613(23)00366-7 [pii] LID - 10.1016/j.immuni.2023.08.010 [doi] AB - The immune and nervous systems respond to dangerous stimuli to maintain homeostasis. In a recent issue of Nature, Florsheim et al. and Plum et al. uncover the crosstalk between immunoglobulin E (IgE)-mast-cell-mediated immune activation and neural responses driving behavioral avoidance of allergenic food. CI - Copyright (c) 2023 Elsevier Inc. All rights reserved. FAU - Miranda-Waldetario, Mariana C G AU - Miranda-Waldetario MCG AD - Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, and Lipschultz Precision Immunology Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: mariana.waldetario@mssm.edu. FAU - Curotto de Lafaille, Maria A AU - Curotto de Lafaille MA AD - Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, and Lipschultz Precision Immunology Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: maria.lafaille@mssm.edu. LA - eng PT - Comment PT - Journal Article PL - United States TA - Immunity JT - Immunity JID - 9432918 RN - 37341-29-0 (Immunoglobulin E) SB - IM CON - Nature. 2023 Aug;620(7974):643-650. PMID: 37437602 CON - Nature. 2023 Aug;620(7974):634-642. PMID: 37438525 MH - Humans MH - *Mast Cells MH - *Food Hypersensitivity MH - Antigen Presentation MH - Cross Reactions MH - Immunoglobulin E COIS- Declaration of interests The authors declare no competing interests. EDAT- 2023/09/14 00:42 MHDA- 2023/09/15 06:43 CRDT- 2023/09/13 18:17 PHST- 2023/08/16 00:00 [received] PHST- 2023/08/16 00:00 [accepted] PHST- 2023/09/15 06:43 [medline] PHST- 2023/09/14 00:42 [pubmed] PHST- 2023/09/13 18:17 [entrez] AID - S1074-7613(23)00366-7 [pii] AID - 10.1016/j.immuni.2023.08.010 [doi] PST - ppublish SO - Immunity. 2023 Sep 12;56(9):1988-1990. doi: 10.1016/j.immuni.2023.08.010.