PMID- 37714053
OWN - NLM
STAT- Publisher
LR  - 20231016
IS  - 1878-0334 (Electronic)
IS  - 1871-4021 (Linking)
VI  - 17
IP  - 9
DP  - 2023 Sep
TI  - Diabetes burden, trends, and inequalities in western pacific region, 1990-2019: A 
      population-based study.
PG  - 102852
LID - S1871-4021(23)00148-0 [pii]
LID - 10.1016/j.dsx.2023.102852 [doi]
AB  - AIMS: The aim was to describe the diabetes regional burden, trends, and 
      inequalities in the Western Pacific region. METHODS: The Global Burden of Disease 
      2019 study was used to evaluate the prevalence, incidence, mortality, 
      disability-adjusted life year (DALY) rates and average annual percentage changes 
      (AAPCs) in diabetes in the Western Pacific region from 1990 to 2019. 
      Cross-country inequalities in the DALY rates of diabetes were estimated between 
      1990 and 2019. RESULTS: The age-standardized incidence of type 1 diabetes 
      mellitus (T1DM) and type 2 diabetes mellitus (T2DM) in the Western Pacific region 
      increased from 2.6 to 3.8 per 100,000 population (AAPC, 0.97 [95% CI 0.84 to 
      1.1]) and from 174.8 to 207.3 per 100,000 population (AAPC, 0.63 [95% CI 0.48 to 
      0.77]) between 1990 and 2019, respectively. The most substantial increase in the 
      incidence of T1DM and T2DM was found in the groups aged 70 years and older (AAPC, 
      2.38 [95% CI 2.19 to 2.58]) and 15-49 years (AAPC, 1.58 [95% CI 1.43 to 1.72]) 
      from 1990 to 2019, respectively. Age-standardized DALYs for T1DM decreased but 
      those for T2DM increased between 1990 and 2019. The relative concentration index 
      of DALYs in T1DM and T2DM changed from 0.11 in 1990 to -0.08 in 2019 and from 
      0.03 in 1990 to -0.04 in 2019, respectively. CONCLUSIONS: Over three decades, 
      diabetes incidence in the Western Pacific region rose substantially, with 
      inequalities among countries. The burden shifted from higher to lower 
      sociodemographic index countries. Diabetes remains a public health challenge, 
      especially among young populations. Urgent interventions for prevention and early 
      detection are crucial.
CI  - Copyright (c) 2023 Research Trust of DiabetesIndia (DiabetesIndia) and National 
      Diabetes Obesity and Cholesterol Foundation (N-DOC). Published by Elsevier Ltd. 
      All rights reserved.
FAU - Cao, Yanli
AU  - Cao Y
AD  - Department of Endocrinology and Metabolism, The Institute of Endocrinology, NHC 
      Key Laboratory of Diagnosis and Treatment of Thyroid Disease, The First Hospital 
      of China Medical University, Shenyang, Liaoning, China.
FAU - Jin, Chenye
AU  - Jin C
AD  - Department of Rheumatology and Immunology, The First Hospital of China Medical 
      University, Shenyang, Liaoning, China.
FAU - Zhang, Jing
AU  - Zhang J
AD  - Department of Biostatistics and Epidemiology, School of Public Health, Health 
      Science Center, Shenzhen University, Shenzhen, Guangdong, China.
FAU - Sun, Hao
AU  - Sun H
AD  - Department of Clinical Epidemiology and Evidence-based Medicine, The First 
      Hospital of China Medical University, Shenyang, Liaoning, China.
FAU - Ma, Bing
AU  - Ma B
AD  - Department of Clinical Epidemiology and Evidence-based Medicine, The First 
      Hospital of China Medical University, Shenyang, Liaoning, China.
FAU - Yang, Xue
AU  - Yang X
AD  - Department of Endocrinology and Metabolism, The Institute of Endocrinology, NHC 
      Key Laboratory of Diagnosis and Treatment of Thyroid Disease, The First Hospital 
      of China Medical University, Shenyang, Liaoning, China.
FAU - Liu, Tingting
AU  - Liu T
AD  - Department of Endocrinology and Metabolism, The Institute of Endocrinology, NHC 
      Key Laboratory of Diagnosis and Treatment of Thyroid Disease, The First Hospital 
      of China Medical University, Shenyang, Liaoning, China.
FAU - Yang, Kaijie
AU  - Yang K
AD  - Department of Endocrinology and Metabolism, The Institute of Endocrinology, NHC 
      Key Laboratory of Diagnosis and Treatment of Thyroid Disease, The First Hospital 
      of China Medical University, Shenyang, Liaoning, China.
FAU - Li, Yongze
AU  - Li Y
AD  - Department of Endocrinology and Metabolism, The Institute of Endocrinology, NHC 
      Key Laboratory of Diagnosis and Treatment of Thyroid Disease, The First Hospital 
      of China Medical University, Shenyang, Liaoning, China. Electronic address: 
      yzli87@cmu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20230911
PL  - Netherlands
TA  - Diabetes Metab Syndr
JT  - Diabetes & metabolic syndrome
JID - 101462250
SB  - IM
OTO - NOTNLM
OT  - Diabetes
OT  - Disease burden
OT  - Epidemiology
OT  - Inequalities
OT  - Western pacific region
COIS- Declaration of competing interest We declare no competing interests.
EDAT- 2023/09/16 05:41
MHDA- 2023/09/16 05:41
CRDT- 2023/09/15 18:10
PHST- 2023/05/18 00:00 [received]
PHST- 2023/09/01 00:00 [revised]
PHST- 2023/09/05 00:00 [accepted]
PHST- 2023/09/16 05:41 [pubmed]
PHST- 2023/09/16 05:41 [medline]
PHST- 2023/09/15 18:10 [entrez]
AID - S1871-4021(23)00148-0 [pii]
AID - 10.1016/j.dsx.2023.102852 [doi]
PST - ppublish
SO  - Diabetes Metab Syndr. 2023 Sep;17(9):102852. doi: 10.1016/j.dsx.2023.102852. Epub 
      2023 Sep 11.