PMID- 37718296
OWN - NLM
STAT- MEDLINE
DCOM- 20230919
LR  - 20231223
IS  - 1833-3516 (Print)
IS  - 2209-1491 (Electronic)
IS  - 1833-3516 (Linking)
VI  - 53
IP  - 3
DP  - 2023 Sep 30
TI  - Outcomes of hyperbaric oxygen treatment for central and branch retinal artery 
      occlusion at a major Australian referral hospital.
PG  - 224-229
LID - 10.28920/dhm53.3.224-229 [doi]
AB  - INTRODUCTION: This study analysed the treatment outcomes of patients that 
      received hyperbaric oxygen treatment (HBOT) for retinal artery occlusion (RAO) at 
      the Royal Brisbane and Women's Hospital in Brisbane, Australia between 2015 and 
      2021. METHODS: Retrospective study from patient records including 22 eyes from 22 
      patients that received HBOT for either central RAO (17 patients) or branch RAO 
      (five patients). Patients received the Royal Brisbane and Women's Hospital RAO 
      protocol for their HBOT. Analysis included best corrected visual acuity pre- and 
      post-treatment, subjective improvements, side effects and patient risk factors 
      were also recorded. RESULTS: Improvement in best corrected visual acuity was 
      LogMAR -0.2 for central RAO on average with 8/17 (47%) experiencing objective 
      improvement, 5/17 (29%) experienced no change and 4/22 (24%) experienced a 
      reduction in best corrected visual acuity. Subjective improvement (colour 
      perception or visual fields) was reported in an additional 4/17 patients, 
      resulting in 12/17 (71%) reporting improvement either in visual acuity or 
      subjectively. There was no improvement in the best corrected visual acuity of any 
      of the five patients suffering from branch RAO. Cardiovascular risk factors 
      present in the cohort included hypertension, hypercholesterolaemia, previous 
      cardiovascular events, cardiac disease and smoking. Limited side effects were 
      experienced by this patient cohort with no recorded irreversible side effects. 
      CONCLUSIONS: Hyperbaric oxygen treatment appears a safe, beneficial treatment for 
      central RAO. No benefit was demonstrated in branch RAO although numbers were 
      small. Increased awareness of HBOT for RAO resulting in streamlined referrals and 
      transfers and greater uptake of this intervention may further improve patient 
      outcomes.
CI  - Copyright: This article is the copyright of the authors who grant Diving and 
      Hyperbaric Medicine a non-exclusive licence to publish the article in electronic 
      and other forms.
FAU - Williamson, Jeremy
AU  - Williamson J
AD  - Department of Ophthalmology, Royal Brisbane and Women's Hospital, Brisbane, 
      Australia.
FAU - Sharma, Anil
AU  - Sharma A
AD  - Department of Ophthalmology, Royal Brisbane and Women's Hospital, Brisbane, 
      Australia.
FAU - Murray-Douglass, Alexander
AU  - Murray-Douglass A
AD  - Department of Ophthalmology, Royal Brisbane and Women's Hospital, Brisbane, 
      Australia.
FAU - Peters, Matthew
AU  - Peters M
AD  - Department of Ophthalmology, Royal Brisbane and Women's Hospital, Brisbane, 
      Australia.
FAU - Lee, Lawrence
AU  - Lee L
AD  - Department of Ophthalmology, Royal Brisbane and Women's Hospital, Brisbane, 
      Australia.
FAU - Webb, Robert
AU  - Webb R
AD  - Department of Hyperbaric Medicine, Royal Brisbane and Women's Hospital, Brisbane, 
      Australia.
FAU - Thistlethwaite, Kenneth
AU  - Thistlethwaite K
AD  - Department of Hyperbaric Medicine, Royal Brisbane and Women's Hospital, Brisbane, 
      Australia.
FAU - Moloney, Thomas P
AU  - Moloney TP
AD  - Department of Ophthalmology, Royal Brisbane and Women's Hospital, Brisbane, 
      Australia.
AD  - School of Medicine, University of Queensland, Brisbane, Australia.
AD  - Corresponding author: Dr Thomas P Moloney, Department of Ophthalmology, Royal 
      Brisbane and Women's Hospital, Brisbane, Australia, t.moloney@uq.edu.au.
LA  - eng
PT  - Journal Article
PL  - Australia
TA  - Diving Hyperb Med
JT  - Diving and hyperbaric medicine
JID - 101282742
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Humans
MH  - Female
MH  - *Hyperbaric Oxygenation
MH  - Oxygen
MH  - Retrospective Studies
MH  - Australia
MH  - *Retinal Artery Occlusion/therapy
MH  - Hospitals
PMC - PMC10735708
OTO - NOTNLM
OT  - Blindness
OT  - Circulation
OT  - Ophthalmology
OT  - Retinal artery occlusion
COIS- Conflict of interest and funding: nil
EDAT- 2023/09/18 00:41
MHDA- 2023/09/19 06:42
PMCR- 2024/09/30
CRDT- 2023/09/17 22:53
PHST- 2023/01/18 00:00 [received]
PHST- 2023/05/14 00:00 [accepted]
PHST- 2024/09/30 00:00 [pmc-release]
PHST- 2023/09/19 06:42 [medline]
PHST- 2023/09/18 00:41 [pubmed]
PHST- 2023/09/17 22:53 [entrez]
AID - 10.28920/dhm53.3.224-229 [doi]
PST - ppublish
SO  - Diving Hyperb Med. 2023 Sep 30;53(3):224-229. doi: 10.28920/dhm53.3.224-229.