PMID- 37719918
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230920
IS  - 1831-4732 (Electronic)
IS  - 1831-4732 (Linking)
VI  - 21
IP  - 9
DP  - 2023 Sep
TI  - Modification of the existing maximum residue levels for mefentrifluconazole in 
      various commodities.
PG  - e08237
LID - 10.2903/j.efsa.2023.8237 [doi]
LID - e08237
AB  - In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant BASF 
      Agro B.V. Arnhem (NL) Freienbach Branch submitted a request to the competent 
      national authority in Austria to modify the existing maximum residue levels 
      (MRLs) for the active substance mefentrifluconazole in various crops and swine 
      liver and other swine products. The data submitted in support of the request were 
      found to be sufficient to derive MRL proposals. Adequate analytical methods for 
      enforcement are available to control the residues of mefentrifluconazole in the 
      plant commodities under consideration and in animal matrices at the validated 
      limit of quantification (LOQ) of 0.01 mg/kg. New data relevant to the data gaps 
      on storage stability and feeding studies of triazole derivative metabolites 
      (TDMs), that were identified during the peer review of confirmatory data of the 
      TDMs, were submitted in support of the present MRL application. Based on the risk 
      assessment results, EFSA concluded that the short-term and long-term intake of 
      residues resulting from the use of mefentrifluconazole according to the reported 
      agricultural practices is unlikely to present a risk to consumer health. EFSA 
      noted a narrow safety margin with regard to acute exposure to mefentrifluconazole 
      residues from the intake of spinaches if residues occur at the level of the 
      proposed MRL. EFSA also performed an indicative risk assessment for the TDMs 
      based on uses of mefentrifluconazole only. The estimated exposure for TDMs did 
      not exceed the toxicological reference values.
CI  - (c) 2023 European Food Safety Authority. EFSA Journal published by Wiley-VCH GmbH 
      on behalf of European Food Safety Authority.
CN  - EFSA (European Food Safety Authority)
FAU - Bellisai, Giulia
AU  - Bellisai G
FAU - Bernasconi, Giovanni
AU  - Bernasconi G
FAU - Carrasco Cabrera, Luis
AU  - Carrasco Cabrera L
FAU - Castellan, Irene
AU  - Castellan I
FAU - Del Aguila, Monica
AU  - Del Aguila M
FAU - Ferreira, Lucien
AU  - Ferreira L
FAU - Santonja, German Giner
AU  - Santonja GG
FAU - Greco, Luna
AU  - Greco L
FAU - Jarrah, Samira
AU  - Jarrah S
FAU - Leuschner, Renata
AU  - Leuschner R
FAU - Perez, Javier Martinez
AU  - Perez JM
FAU - Miron, Ileana
AU  - Miron I
FAU - Nave, Stefanie
AU  - Nave S
FAU - Pedersen, Ragnor
AU  - Pedersen R
FAU - Reich, Hermine
AU  - Reich H
FAU - Ruocco, Silvia
AU  - Ruocco S
FAU - Santos, Miguel
AU  - Santos M
FAU - Scarlato, Alessia Pia
AU  - Scarlato AP
FAU - Theobald, Anne
AU  - Theobald A
FAU - Tiramani, Manuela
AU  - Tiramani M
FAU - Verani, Alessia
AU  - Verani A
LA  - eng
PT  - Journal Article
DEP - 20230915
PL  - United States
TA  - EFSA J
JT  - EFSA journal. European Food Safety Authority
JID - 101642076
PMC - PMC10502649
OTO - NOTNLM
OT  - MRL
OT  - Mefentrifluconazole
OT  - consumer risk assessment
OT  - honey
OT  - livestock
OT  - pesticide
OT  - various crops
EDAT- 2023/09/18 06:42
MHDA- 2023/09/18 06:43
PMCR- 2023/09/15
CRDT- 2023/09/18 04:30
PHST- 2023/09/18 06:43 [medline]
PHST- 2023/09/18 06:42 [pubmed]
PHST- 2023/09/18 04:30 [entrez]
PHST- 2023/09/15 00:00 [pmc-release]
AID - EFS28237 [pii]
AID - 10.2903/j.efsa.2023.8237 [doi]
PST - epublish
SO  - EFSA J. 2023 Sep 15;21(9):e08237. doi: 10.2903/j.efsa.2023.8237. eCollection 2023 
      Sep.