PMID- 37721206
OWN - NLM
STAT- MEDLINE
DCOM- 20230929
LR  - 20231013
IS  - 1759-9679 (Electronic)
IS  - 1759-9660 (Linking)
VI  - 15
IP  - 37
DP  - 2023 Sep 28
TI  - A quantum dot aptamer fluorescent sensor based on magnetic graphene oxide for the 
      detection of zearalenone.
PG  - 4946-4953
LID - 10.1039/d3ay01260c [doi]
AB  - As an estrogenic mycotoxin found in a wide range of agricultural crops, the 
      toxicity of zearalenone (ZEN) poses a serious risk to human health. Accordingly, 
      to achieve rapid detection of zearalenone in complex samples, an aptamer 
      fluorescence sensor based on magnetic graphene oxide was developed. Compared with 
      traditional methods, this technique has the virtues of simple operation, low 
      cost, and reliable performance. Magnetic graphene oxide (MGO) was synthesized as 
      a fluorescent bursting agent, using a chemical precipitation approach by 
      depositing Fe(3)O(4) on the surface of graphene oxide. As a fluorescent probe, an 
      aptamer coupling with CdTe quantum dots and zearalenone was used. Following the 
      specific binding of zearalenone and the aptamer, the affinity interaction between 
      the fluorescent probe and MGO was weakened, resulting in the recovery of 
      fluorescence and making the qualitative and quantitative analysis of zearalenone 
      available via fluorescence intensity determination. The results indicated that 
      the method's linear range was 5-120 mug L(-1) and its detection limit was 2.9 mug 
      L(-1). In addition, the recoveries varied from 76.4 to 118.8% for crop samples, 
      with relative standard deviations (RSDs) between 0.8 and 9.5%, which suggests an 
      effective method for the separation and detection of mycotoxins in actual 
      environmental samples.
FAU - Liao, Xianglin
AU  - Liao X
AUID- ORCID: 0009-0002-2780-5469
AD  - Guangzhou Key Laboratory of Analytical Chemistry for Biomedicine, GDMPA Key 
      Laboratory for Process Control and Quality Evaluation of Chiral Pharmaceuticals, 
      School of Chemistry, South China Normal University, Guangzhou, P. R. China. 
      huxg@scnu.edu.cn.
FAU - Liu, Yimin
AU  - Liu Y
AD  - Guangzhou Key Laboratory of Analytical Chemistry for Biomedicine, GDMPA Key 
      Laboratory for Process Control and Quality Evaluation of Chiral Pharmaceuticals, 
      School of Chemistry, South China Normal University, Guangzhou, P. R. China. 
      huxg@scnu.edu.cn.
FAU - Qiu, Liyu
AU  - Qiu L
AD  - Guangzhou Key Laboratory of Analytical Chemistry for Biomedicine, GDMPA Key 
      Laboratory for Process Control and Quality Evaluation of Chiral Pharmaceuticals, 
      School of Chemistry, South China Normal University, Guangzhou, P. R. China. 
      huxg@scnu.edu.cn.
FAU - Cao, Lu
AU  - Cao L
AD  - Guangzhou Key Laboratory of Analytical Chemistry for Biomedicine, GDMPA Key 
      Laboratory for Process Control and Quality Evaluation of Chiral Pharmaceuticals, 
      School of Chemistry, South China Normal University, Guangzhou, P. R. China. 
      huxg@scnu.edu.cn.
FAU - Yang, Xixiang
AU  - Yang X
AUID- ORCID: 0000-0003-4109-9505
AD  - Guangzhou Key Laboratory of Analytical Chemistry for Biomedicine, GDMPA Key 
      Laboratory for Process Control and Quality Evaluation of Chiral Pharmaceuticals, 
      School of Chemistry, South China Normal University, Guangzhou, P. R. China. 
      huxg@scnu.edu.cn.
FAU - Hu, Xiaogang
AU  - Hu X
AD  - Guangzhou Key Laboratory of Analytical Chemistry for Biomedicine, GDMPA Key 
      Laboratory for Process Control and Quality Evaluation of Chiral Pharmaceuticals, 
      School of Chemistry, South China Normal University, Guangzhou, P. R. China. 
      huxg@scnu.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230928
PL  - England
TA  - Anal Methods
JT  - Analytical methods : advancing methods and applications
JID - 101519733
RN  - 5W827M159J (Zearalenone)
RN  - 0 (graphene oxide)
RN  - STG188WO13 (cadmium telluride)
RN  - 0 (Cadmium Compounds)
RN  - 0 (Fluorescent Dyes)
RN  - 3A3U0GI71G (Magnesium Oxide)
RN  - NQA0O090ZJ (Tellurium)
RN  - 0 (Mycotoxins)
RN  - 0 (Aptamers, Nucleotide)
SB  - IM
MH  - Humans
MH  - *Zearalenone/analysis
MH  - *Quantum Dots
MH  - *Cadmium Compounds
MH  - Fluorescent Dyes
MH  - Magnesium Oxide
MH  - Limit of Detection
MH  - Tellurium
MH  - *Mycotoxins/analysis
MH  - *Aptamers, Nucleotide
MH  - Magnetic Phenomena
EDAT- 2023/09/18 12:42
MHDA- 2023/09/29 06:43
CRDT- 2023/09/18 06:53
PHST- 2023/09/29 06:43 [medline]
PHST- 2023/09/18 12:42 [pubmed]
PHST- 2023/09/18 06:53 [entrez]
AID - 10.1039/d3ay01260c [doi]
PST - epublish
SO  - Anal Methods. 2023 Sep 28;15(37):4946-4953. doi: 10.1039/d3ay01260c.