PMID- 37722017 OWN - NLM STAT- MEDLINE DCOM- 20240223 LR - 20240223 IS - 2153-7933 (Electronic) IS - 2153-7658 (Print) IS - 2153-7658 (Linking) VI - 13 IP - 4 DP - 2023 Dec TI - Successful Therapeutic Hypothermia in a Patient with Drug-Induced J Waves and Cardiac Arrest: A Case Report. PG - 230-233 LID - 10.1089/ther.2023.0041 [doi] AB - A 50-year-old man was admitted to our hospital with hypotension and bradycardia after receiving high doses of atenolol, amlodipine, and etizolam. He had a drug-induced J wave on electrocardiography and subsequently underwent cardiac arrest. The patient was successfully rescued by venoarterial extracorporeal membrane oxygenation (VA-ECMO) and a good neurological outcome was achieved with therapeutic hypothermia (TH). In patients with J waves, TH is thought to increase the J waves and cause fatal arrhythmias, but in this case, rapid cooling with VA-ECMO allowed the patient to successfully complete TH. FAU - Sato, Jun AU - Sato J AUID- ORCID: 0000-0002-1120-8312 AD - Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, Tokyo, Japan. FAU - Yagi, Tsukasa AU - Yagi T AD - Division of Cardiology, Department of Internal Medicine, Nihon University Hospital, Tokyo, Japan. FAU - Shimada, Erika AU - Shimada E AD - Division of Cardiology, Department of Internal Medicine, Nihon University Hospital, Tokyo, Japan. FAU - Kobori, Masashi AU - Kobori M AD - Division of Cardiology, Department of Internal Medicine, Nihon University Hospital, Tokyo, Japan. FAU - Watanabe, Kazuhiro AU - Watanabe K AD - Division of Cardiology, Department of Internal Medicine, Nihon University Hospital, Tokyo, Japan. FAU - Kuwana, Tsukasa AU - Kuwana T AD - Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, Tokyo, Japan. FAU - Chiba, Nobutaka AU - Chiba N AD - Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, Tokyo, Japan. FAU - Saito, Takeshi AU - Saito T AD - Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, Tokyo, Japan. FAU - Kinoshita, Kosaku AU - Kinoshita K AUID- ORCID: 0000-0002-9451-9027 AD - Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, Tokyo, Japan. LA - eng PT - Case Reports PT - Journal Article DEP - 20230919 PL - United States TA - Ther Hypothermia Temp Manag JT - Therapeutic hypothermia and temperature management JID - 101543518 SB - IM MH - Humans MH - Male MH - Middle Aged MH - *Cardiopulmonary Resuscitation MH - Cold Temperature MH - *Extracorporeal Membrane Oxygenation MH - *Heart Arrest/chemically induced/therapy MH - *Hypothermia, Induced MH - Treatment Outcome PMC - PMC10698792 OTO - NOTNLM OT - J wave OT - beta-blocker OT - calcium channel blocker OT - extracorporeal cardiopulmonary resuscitation OT - therapeutic hypothermia COIS- No competing financial interests exist. EDAT- 2023/09/18 18:42 MHDA- 2023/12/04 12:43 PMCR- 2023/11/30 CRDT- 2023/09/18 15:06 PHST- 2023/12/04 12:43 [medline] PHST- 2023/09/18 18:42 [pubmed] PHST- 2023/09/18 15:06 [entrez] PHST- 2023/11/30 00:00 [pmc-release] AID - 10.1089/ther.2023.0041 [pii] AID - 10.1089/ther.2023.0041 [doi] PST - ppublish SO - Ther Hypothermia Temp Manag. 2023 Dec;13(4):230-233. doi: 10.1089/ther.2023.0041. Epub 2023 Sep 19.