PMID- 37737711
OWN - NLM
STAT- MEDLINE
DCOM- 20231109
LR  - 20231109
IS  - 1651-2251 (Electronic)
IS  - 0001-6489 (Linking)
VI  - 143
IP  - 9
DP  - 2023 Sep
TI  - Type 2 diabetes mellitus increases postoperative recurrence risk in Chinese 
      patients with chronic rhinosinusitis.
PG  - 783-788
LID - 10.1080/00016489.2023.2255222 [doi]
AB  - BACKGROUND: The effect of type 2 diabetes mellitus (T2DM) on postoperative 
      recurrence of chronic sinusitis (CRS) is unclear. OBJECTIVE: To investigate the 
      association between T2DM and postoperative recurrence in CRS patients. METHODS: 
      CRS patients who underwent surgery in our hospital from January 2018 to April 
      2020 were included and followed up for three years. Patients were classified into 
      non-recurrent and recurrent CRS groups based on follow-up outcome, and logistic 
      regression analysis was performed to identify risk factors for postoperative 
      recurrence. RESULTS: A total of 412 CRS patients were included of whom 68 had 
      T2DM. The postoperative recurrence rate was significantly higher in the T2DM 
      group compared to the non-T2DM group (p < .05). T2DM prevalence and fasting blood 
      glucose (FBG) levels were higher in recurrent CRS patients than those in 
      non-recurrent CRS cases (p < .05). Multivariate regression analyses showed that 
      age, duration of disease, FBG, and comorbid allergic rhinitis (AR) were 
      significantly associated with an increased risk of postoperative recurrence of 
      CRS (p < .05). Furthermore, adjusted logistic regression model revealed that T2DM 
      was an independent risk factor for postoperative recurrence of CRS (p < .05). 
      CONCLUSIONS: Elevated FBG levels may significantly influenced the postoperative 
      recurrence of CRS in Chinese patients, and T2DM was an independent risk factor 
      for recurrence.
FAU - Luo, Mengfei
AU  - Luo M
AD  - Department of Otolaryngology Head and Neck Surgery, The Center Hospital of Loudi 
      City, Loudi, PR China.
FAU - Zhou, En
AU  - Zhou E
AD  - Department of Otolaryngology Head and Neck Surgery, Hunan Provincial People's 
      Hospital, Changsha, PR China.
FAU - Peng, Fusen
AU  - Peng F
AD  - Department of Otolaryngology Head and Neck Surgery, The Center Hospital of Loudi 
      City, Loudi, PR China.
LA  - eng
PT  - Journal Article
DEP - 20231108
PL  - England
TA  - Acta Otolaryngol
JT  - Acta oto-laryngologica
JID - 0370354
SB  - IM
MH  - Humans
MH  - *Diabetes Mellitus, Type 2/complications/epidemiology
MH  - *Rhinitis/complications/epidemiology/surgery
MH  - East Asian People
MH  - *Sinusitis/complications/epidemiology/surgery
MH  - Chronic Disease
OTO - NOTNLM
OT  - Chronic rhinosinusitis
OT  - fasting blood glucose
OT  - recurrence
OT  - surgery
OT  - type 2 diabetes mellitus
EDAT- 2023/09/22 12:43
MHDA- 2023/11/09 06:42
CRDT- 2023/09/22 10:40
PHST- 2023/11/09 06:42 [medline]
PHST- 2023/09/22 12:43 [pubmed]
PHST- 2023/09/22 10:40 [entrez]
AID - 10.1080/00016489.2023.2255222 [doi]
PST - ppublish
SO  - Acta Otolaryngol. 2023 Sep;143(9):783-788. doi: 10.1080/00016489.2023.2255222. 
      Epub 2023 Nov 8.