PMID- 37741440
OWN - NLM
STAT- MEDLINE
DCOM- 20240326
LR  - 20240326
IS  - 1877-0568 (Electronic)
IS  - 1877-0568 (Linking)
VI  - 110
IP  - 2
DP  - 2024 Apr
TI  - Defining the minimum clinically important difference (MCID) in the hospital 
      anxiety and depression scale (HADS) in patients undergoing total hip and knee 
      arthroplasty.
PG  - 103689
LID - S1877-0568(23)00198-6 [pii]
LID - 10.1016/j.otsr.2023.103689 [doi]
AB  - INTRODUCTION: Total hip (THA) and knee (TKA) arthroplasty are effective 
      procedures, but whose success depends on various factors, including patients' 
      genetics, sociocultural environments, and psychological factors. Patient-reported 
      outcome measures (PROMs) provide objective health status outcomes measurements, 
      whose lowest significant variation is detected by the minimum clinically 
      important difference (MCID). HYPOTHESIS: We aimed to find the MCID scores for the 
      Hospital Anxiety and Depression Scale (HADS), HADS-A, and HADS-D in a cohort of 
      individuals undergoing THA or TKA. PATIENTS AND METHODS: We enrolled 88 patients 
      suffering from osteoarthritis (43 undergoing THA, and 45 TKA) by administering 
      HADS, SF-12 and WOMAC at baseline and then with a 12-month prospective follow-up. 
      The MCID for HADS, HADS-A, and HADS-D was calculated using the distribution-based 
      approach, according to various techniques (0.5 standard deviation [0.5 SD]), the 
      standard error of measurement (SEM), the effect size (ES), and the minimum 
      detectable change (MDC). RESULTS: The analysis of HADS, HADS-A, and HADS-D scores 
      revealed clinically significant improvements in symptoms in patients who 
      underwent THA and TKA. The MCID range values were determined to be between 
      2.7-8.5 for the HADS, 1.4-4.4 for the HADS-A, and 1.5-4.8 for the HADS-D in the 
      group of patients undergoing THA, and 2.1-6.7 for the HADS, 1.2-3.8 for the 
      HADS-A, and 1.1-3.6 for the HADS-D in the TKA group. DISCUSSION: The study 
      determined significant improvement in all scores applying MCID analysis, which 
      can aid physicians in interpreting anxiety and depression scores and developing 
      both preoperative and postoperative procedures to enhance outcomes for patients 
      undergoing THA and TKA. LEVEL OF EVIDENCE: I; well-designed cohort study.
CI  - Copyright (c) 2023 The Author(s). Published by Elsevier Masson SAS.. All rights 
      reserved.
FAU - de Filippis, Renato
AU  - de Filippis R
AD  - Psychiatry Unit, Department of Health Sciences, University Magna Graecia of 
      Catanzaro, 88100 Catanzaro, Italy.
FAU - Mercurio, Michele
AU  - Mercurio M
AD  - Department of Orthopaedic and Trauma Surgery, "Magna Graecia" University, "Mater 
      Domini" University Hospital, V. le Europa, 88100 Catanzaro, Italy. Electronic 
      address: mercuriomi@gmail.com.
FAU - Segura-Garcia, Cristina
AU  - Segura-Garcia C
AD  - Psychiatry Unit, Department of Medical and Surgical Sciences, University Magna 
      Graecia of Catanzaro, 88100 Catanzaro, Italy.
FAU - De Fazio, Pasquale
AU  - De Fazio P
AD  - Psychiatry Unit, Department of Health Sciences, University Magna Graecia of 
      Catanzaro, 88100 Catanzaro, Italy.
FAU - Gasparini, Giorgio
AU  - Gasparini G
AD  - Department of Orthopaedic and Trauma Surgery, "Magna Graecia" University, "Mater 
      Domini" University Hospital, V. le Europa, 88100 Catanzaro, Italy.
FAU - Galasso, Olimpio
AU  - Galasso O
AD  - Department of Orthopaedic and Trauma Surgery, "Magna Graecia" University, "Mater 
      Domini" University Hospital, V. le Europa, 88100 Catanzaro, Italy.
LA  - eng
PT  - Journal Article
DEP - 20230921
PL  - France
TA  - Orthop Traumatol Surg Res
JT  - Orthopaedics & traumatology, surgery & research : OTSR
JID - 101494830
SB  - IM
MH  - Humans
MH  - *Arthroplasty, Replacement, Knee/adverse effects
MH  - Cohort Studies
MH  - Prospective Studies
MH  - Depression/diagnosis
MH  - *Arthroplasty, Replacement, Hip/psychology
MH  - Hospitals
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Anxiety
OT  - Depression
OT  - Psychological factors
OT  - Total hip arthroplasty (THA)
OT  - Total knee arthroplasty (TKA)
EDAT- 2023/09/24 00:42
MHDA- 2024/03/26 06:44
CRDT- 2023/09/23 19:15
PHST- 2023/06/06 00:00 [received]
PHST- 2023/08/02 00:00 [revised]
PHST- 2023/08/30 00:00 [accepted]
PHST- 2024/03/26 06:44 [medline]
PHST- 2023/09/24 00:42 [pubmed]
PHST- 2023/09/23 19:15 [entrez]
AID - S1877-0568(23)00198-6 [pii]
AID - 10.1016/j.otsr.2023.103689 [doi]
PST - ppublish
SO  - Orthop Traumatol Surg Res. 2024 Apr;110(2):103689. doi: 
      10.1016/j.otsr.2023.103689. Epub 2023 Sep 21.