PMID- 3774224
OWN - NLM
STAT- MEDLINE
DCOM- 19861217
LR  - 20190701
IS  - 0304-3940 (Print)
IS  - 0304-3940 (Linking)
VI  - 70
IP  - 1
DP  - 1986 Sep 25
TI  - The effect of naloxone on sexual behavior in female rats depends on the site of 
      injection.
PG  - 97-100
AB  - Intraperitoneal injections of the opiate receptor antagonist naloxone (0.1, 1, 5 
      or 10 mg) had no effects on sexual behavior in ovariectomized female rats made 
      either partially or fully receptive by injections of ovarian hormones. 
      Intracerebroventricular (i.c.v.) injections of naloxone (10, 50 or 100 
      micrograms) had no effects on the behavior of partially receptive rats and in 
      fully receptive rats an i.c.v. injection of a high dose of naloxone (100 
      micrograms) inhibited the behavior. Intrathecal (i.t.) injections of naloxone (50 
      or 100 micrograms) facilitated sexual behavior in partially receptive rats while 
      i.t. injections of even very high doses of naloxone (500 micrograms) had no 
      behavioral effects in fully receptive rats. Thus, the effects of naloxone on 
      female sexual behavior depend on the site of injection.
FAU - Lindblom, C
AU  - Lindblom C
FAU - Forsberg, G
AU  - Forsberg G
FAU - Sodersten, P
AU  - Sodersten P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Ireland
TA  - Neurosci Lett
JT  - Neuroscience letters
JID - 7600130
RN  - 36B82AMQ7N (Naloxone)
RN  - 4G7DS2Q64Y (Progesterone)
RN  - 4TI98Z838E (Estradiol)
SB  - IM
MH  - Animals
MH  - Central Nervous System/*drug effects
MH  - Estradiol/pharmacology
MH  - Female
MH  - Injections, Intraperitoneal
MH  - Injections, Intraventricular
MH  - Injections, Spinal
MH  - Naloxone/*pharmacology
MH  - Ovariectomy
MH  - Posture
MH  - Progesterone/pharmacology
MH  - Rats
MH  - Sexual Behavior, Animal/*drug effects
EDAT- 1986/09/25 00:00
MHDA- 1986/09/25 00:01
CRDT- 1986/09/25 00:00
PHST- 1986/09/25 00:00 [pubmed]
PHST- 1986/09/25 00:01 [medline]
PHST- 1986/09/25 00:00 [entrez]
AID - 0304-3940(86)90444-1 [pii]
AID - 10.1016/0304-3940(86)90444-1 [doi]
PST - ppublish
SO  - Neurosci Lett. 1986 Sep 25;70(1):97-100. doi: 10.1016/0304-3940(86)90444-1.