PMID- 37742304
OWN - NLM
STAT- MEDLINE
DCOM- 20240401
LR  - 20240401
IS  - 1945-5119 (Electronic)
IS  - 1074-9357 (Linking)
VI  - 31
IP  - 4
DP  - 2024 May
TI  - Estimating the minimal clinically important difference of upper extremity outcome 
      measures in chronic stroke patients with moderate to severe impairment: a 
      cross-sectional study.
PG  - 409-417
LID - 10.1080/10749357.2023.2259649 [doi]
AB  - BACKGROUND: Approximately 70% of chronic stroke patients experience upper 
      extremity (UE) functional impairments, and UE outcome measures are often used as 
      quality-of-life indicators. OBJECTIVE: The purpose of this study was to estimate 
      minimal clinically important difference (MCID) values for UE outcome measures in 
      chronic stroke patients with moderate to severe UE hemiplegia. METHODS: This 
      study was a cross-sectional study, conducted as a secondary analysis of data from 
      the ReoGo-J study, a multicenter, prospective, randomized, parallel-group trial 
      of robot-assisted self-training for UE hemiplegia in chronic stroke. The patients 
      were randomized to 1 of 3 treatment groups. Treatment was provided 3 times a week 
      for 10 weeks, and UE outcome measures were evaluated before and after treatment. 
      The anchor-based method was used to estimate MCID values for UE outcome measures, 
      with Stroke Impact Scale (SIS) subscales as anchors. MCID values were estimated 
      by identifying cutoff values in a receiver operating characteristic (ROC) curve. 
      RESULTS: Between-group comparisons of UE outcome measures, based on the 
      clinically important difference (CID) values of SIS subscales, revealed 
      significant differences in both the Amount of Use (AOU) and Quality of Movement 
      (QOM) components of the Motor Activity Log (MAL)-14. The estimated MCID values 
      were 0.89 for the AOU component and 0.77 for the QOM component. CONCLUSIONS: The 
      estimated MCID values for the MAL-14 not only add information regarding the 
      clinical characteristics of the MAL-14 but also facilitate interpretations of 
      changing scores in chronic stroke patients with moderate to severe UE hemiplegia 
      undergoing rehabilitation therapy. STUDY REGISTRATION: 
      https://www.umin.ac.jp/ctr/index.htm (UMIN000022509; 1 July 2016).
FAU - Uchiyama, Yuki
AU  - Uchiyama Y
AD  - Department of Rehabilitation Medicine, School of Medicine, Hyogo Medical 
      University, Hyogo, Japan.
FAU - Takebayashi, Takashi
AU  - Takebayashi T
AD  - Department of Rehabilitation Science, School of Medicine, Osaka Metropolitan 
      University, Osaka, Japan.
FAU - Takahashi, Kayoko
AU  - Takahashi K
AD  - Department of Occupational Therapy, School of Allied Health Science, Kitasato 
      University, Kanagawa, Japan.
FAU - Amano, Satoru
AU  - Amano S
AD  - Department of Occupational Therapy, School of Allied Health Science, Kitasato 
      University, Kanagawa, Japan.
FAU - Gosho, Masahiko
AU  - Gosho M
AD  - Department of Biostatistics, Faculty of Medicine, University of Tsukuba, Tsukuba, 
      Japan.
FAU - Sakai, Masahiro
AU  - Sakai M
AD  - Tsukuba Clinical Research and Development Organization, University of Tsukuba, 
      Tsukuba, Japan.
FAU - Hashimoto, Koichi
AU  - Hashimoto K
AD  - Tsukuba Clinical Research and Development Organization, University of Tsukuba, 
      Tsukuba, Japan.
FAU - Hachisuka, Kenji
AU  - Hachisuka K
AD  - Moji Medical Center, Fukuoka, Japan.
FAU - Domen, Kazuhisa
AU  - Domen K
AD  - Department of Rehabilitation Medicine, School of Medicine, Hyogo Medical 
      University, Hyogo, Japan.
LA  - eng
PT  - Journal Article
DEP - 20230924
PL  - England
TA  - Top Stroke Rehabil
JT  - Topics in stroke rehabilitation
JID - 9439750
SB  - IM
MH  - Humans
MH  - Brain Damage, Chronic/complications
MH  - Cross-Sectional Studies
MH  - Hemiplegia
MH  - Minimal Clinically Important Difference
MH  - Outcome Assessment, Health Care
MH  - Prospective Studies
MH  - Recovery of Function
MH  - *Stroke/complications/therapy
MH  - *Stroke Rehabilitation
MH  - Upper Extremity
OTO - NOTNLM
OT  - Stroke
OT  - minimal clinically important difference
OT  - rehabilitation
OT  - robotics
OT  - upper extremity
EDAT- 2023/09/24 18:41
MHDA- 2024/04/01 06:43
CRDT- 2023/09/24 15:10
PHST- 2024/04/01 06:43 [medline]
PHST- 2023/09/24 18:41 [pubmed]
PHST- 2023/09/24 15:10 [entrez]
AID - 10.1080/10749357.2023.2259649 [doi]
PST - ppublish
SO  - Top Stroke Rehabil. 2024 May;31(4):409-417. doi: 10.1080/10749357.2023.2259649. 
      Epub 2023 Sep 24.