PMID- 37743067
OWN - NLM
STAT- Publisher
LR  - 20230924
IS  - 2234-2400 (Print)
IS  - 2234-2400 (Linking)
DP  - 2023 Sep 8
TI  - Comparison of 19-gauge conventional and Franseen needles for the diagnosis of 
      lymphadenopathy and classification of malignant lymphoma using endoscopic 
      ultrasound fine-needle aspiration.
LID - 10.5946/ce.2023.095 [doi]
AB  - BACKGROUND/AIMS: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) 
      using a 19-gauge needle is an efficient sampling method for the diagnosis of 
      lymphadenopathy. This study compared 19-gauge conventional and Franseen needles 
      for the diagnosis of lymphadenopathy and classification of malignant lymphoma 
      (ML). METHODS: Patient characteristics, number of needle passes, puncture route, 
      sensitivity, specificity, and accuracy of cytology/histology for lymphadenopathy 
      were analyzed in patients diagnosed with lymphadenopathy by EUS-FNA using 
      conventional or Franseen needles. RESULTS: Between 2012 and 2022, 146 patients 
      met the inclusion criteria (conventional [n=70] and Franseen [n=76]). The median 
      number of needle passes was significantly lower in the conventional group than in 
      the Franseen group (3 [1-6] vs. 4 [1-6], p=0.023). There were no significant 
      differences in cytological/histological diagnoses between the two groups. For ML, 
      the immunohistochemical evaluation rate, sensitivity of flow cytometry, and 
      cytogenetic assessment were not significantly different in either group. Bleeding 
      adverse events (AEs) were observed in three patients in the Franseen group. 
      CONCLUSIONS: Both the 19-gauge conventional and Franseen needles showed high 
      accuracy in lymphadenopathy and ML classification. Considering sufficient tissue 
      collection and the avoidance of AEs, the use of 19-gauge conventional needles 
      seems to be a good option for the diagnosis of lymphadenopathy.
FAU - Okuno, Mitsuru
AU  - Okuno M
AD  - Department of Gastroenterology, Gifu Municipal Hospital, Gifu, Japan.
FAU - Iwata, Keisuke
AU  - Iwata K
AD  - Department of Gastroenterology, Gifu Municipal Hospital, Gifu, Japan.
FAU - Mukai, Tsuyoshi
AU  - Mukai T
AD  - Department of Gastroenterology, Gifu Municipal Hospital, Gifu, Japan.
AD  - Department of Gastroenterological Endoscopy, Kanazawa Medical University, 
      Ishikawa, Japan.
FAU - Kito, Yusuke
AU  - Kito Y
AD  - Department of Pathology and Translational Research, Gifu University Graduate 
      School of Medicine, Gifu, Japan.
FAU - Tanaka, Takuji
AU  - Tanaka T
AD  - Department of Diagnostic Pathology, Gifu Municipal Hospital, Gifu, Japan.
FAU - Watanabe, Naoki
AU  - Watanabe N
AD  - Department of Diagnostic Pathology, Gifu Municipal Hospital, Gifu, Japan.
FAU - Kasahara, Senji
AU  - Kasahara S
AD  - Department of Hematology, Gifu Municipal Hospital, Gifu, Japan.
FAU - Iwasa, Yuhei
AU  - Iwasa Y
AD  - Department of Gastroenterology, Gifu Municipal Hospital, Gifu, Japan.
FAU - Sugiyama, Akihiko
AU  - Sugiyama A
AD  - Department of Gastroenterology, Gifu Municipal Hospital, Gifu, Japan.
FAU - Nishigaki, Youichi
AU  - Nishigaki Y
AD  - Department of Gastroenterology, Gifu Municipal Hospital, Gifu, Japan.
FAU - Shibata, Yuhei
AU  - Shibata Y
AD  - Department of Hematology, Gifu Municipal Hospital, Gifu, Japan.
FAU - Kitagawa, Junichi
AU  - Kitagawa J
AD  - Department of Hematology, Gifu Municipal Hospital, Gifu, Japan.
FAU - Iwashita, Takuji
AU  - Iwashita T
AD  - First Department of Internal Medicine, Gifu Univeristy Hospital, Gifu, Japan.
FAU - Tomita, Eiichi
AU  - Tomita E
AD  - Department of Gastroenterology, Gifu Municipal Hospital, Gifu, Japan.
FAU - Shimizu, Masahito
AU  - Shimizu M
AD  - First Department of Internal Medicine, Gifu Univeristy Hospital, Gifu, Japan.
LA  - eng
PT  - Journal Article
DEP - 20230908
PL  - Korea (South)
TA  - Clin Endosc
JT  - Clinical endoscopy
JID - 101576886
OTO - NOTNLM
OT  - 19-gauge
OT  - Endoscopic ultrasound-guided fine-needle aspiration
OT  - Franseen needle
OT  - Lymphadenopathy
OT  - Malignant lymphoma
EDAT- 2023/09/25 00:42
MHDA- 2023/09/25 00:42
CRDT- 2023/09/24 20:34
PHST- 2023/03/25 00:00 [received]
PHST- 2023/05/11 00:00 [accepted]
PHST- 2023/09/25 00:42 [medline]
PHST- 2023/09/25 00:42 [pubmed]
PHST- 2023/09/24 20:34 [entrez]
AID - ce.2023.095 [pii]
AID - 10.5946/ce.2023.095 [doi]
PST - aheadofprint
SO  - Clin Endosc. 2023 Sep 8. doi: 10.5946/ce.2023.095.