PMID- 37744321
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230926
IS  - 1948-5190 (Print)
IS  - 1948-5190 (Electronic)
VI  - 15
IP  - 9
DP  - 2023 Sep 16
TI  - Endoscopic Ruler for varix size measurement: A multicenter pilot study.
PG  - 564-573
LID - 10.4253/wjge.v15.i9.564 [doi]
AB  - BACKGROUND: We invented Endoscopic Ruler, a new endoscopic device to measure the 
      size of varices in patients with cirrhosis and portal hypertension. AIM: To 
      assess the feasibility and safety of Endoscopic Ruler, and evaluate the agreement 
      on identifying large oesophageal varices (OV) between Endoscopic Ruler and the 
      endoscopists, as well as the interobserver agreement on diagnosing large OV using 
      Endoscopic Ruler. METHODS: We prospectively and consecutively enrolled patients 
      with cirrhosis from 11 hospitals, all of whom got esophagogastroduodenoscopy 
      (EGD) with Endoscopic Ruler. The primary study outcome was a successful 
      measurement of the size of varices using Endoscopic Ruler. The secondary outcomes 
      included adverse events, operation time, the agreement of identifying large OV 
      between the objective measurement of Endoscopic Ruler and the empirical reading 
      of endoscopists, together with the interobserver agreement on diagnosing large OV 
      by Endoscopic Ruler. RESULTS: From November 2020 to April 2022, a total of 120 
      eligible patients with cirrhosis were recruited and all of them underwent EGD 
      examinations with Endoscopic Ruler successfully without any adverse event. The 
      median operation time of Endoscopic Ruler was 3.00 min [interquartile range 
      (IQR): 3.00 min]. The kappa value between Endoscopic Ruler and the endoscopists 
      while detecting large OV was 0.52, demonstrating a moderate agreement. The kappa 
      value for diagnosing large OV using Endoscopic Ruler among the six independent 
      observers was 0.77, demonstrating a substantial agreement. CONCLUSION: The data 
      demonstrates that Endoscopic Ruler is feasible and safe for measuring the size of 
      varices in patients with cirrhosis and portal hypertension. Endoscopic Ruler is 
      potential to promote the clinical practice of the two-grade classification system 
      of OV.
CI  - (c)The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights 
      reserved.
FAU - Huang, Yi-Fei
AU  - Huang YF
AD  - Institute of Portal Hypertension, The First Hospital of Lanzhou University, 
      Lanzhou 730000, Gansu Province, China.
FAU - Hu, Sheng-Juan
AU  - Hu SJ
AD  - Department of Gastroenterology, People's Hospital of Ningxia Hui Autonomous 
      Region, Ningxia Medical University Affiliated People's Hospital of Autonomous 
      Region, Yinchuan 750000, Ningxia Hui Autonomous Region, China.
FAU - Bu, Yang
AU  - Bu Y
AD  - Department of Gastroenterology, People's Hospital of Ningxia Hui Autonomous 
      Region, Ningxia Medical University Affiliated People's Hospital of Autonomous 
      Region, Yinchuan 750000, Ningxia Hui Autonomous Region, China.
FAU - Li, Yi-Ling
AU  - Li YL
AD  - Department of Gastroenterology, The First Affiliated Hospital of China Medical 
      University, Shenyang 110000, Liaoning Province, China.
FAU - Deng, Yan-Hong
AU  - Deng YH
AD  - Department of Gastroenterology, People's Hospital of Ningxia Hui Autonomous 
      Region, Ningxia Medical University Affiliated People's Hospital of Autonomous 
      Region, Yinchuan 750000, Ningxia Hui Autonomous Region, China.
FAU - Hu, Jian-Ping
AU  - Hu JP
AD  - Department of Gastroenterology, Yinchuan First People's Hospital, Yinchuan 
      750000, Ningxia Hui Autonomous Region, China.
FAU - Yang, Shao-Qi
AU  - Yang SQ
AD  - Department of Gastroenterology, Ningxia Medical University General Hospital, 
      Yinchuan 750000, Ningxia Hui Autonomous Region, China.
FAU - Shen, Qian
AU  - Shen Q
AD  - Department of Gastroenterology, Yinchuan Second People's Hospital, Yinchuan 
      750000, Ningxia Hui Autonomous Region, China.
FAU - McAlindon, Mark
AU  - McAlindon M
AD  - Academic Department of Gastroenterology and Hepatology, Sheffield Teaching 
      Hospitals NHS Trust, AL 35660, Sheffield, United Kingdom.
FAU - Shi, Rui-Chun
AU  - Shi RC
AD  - Department of Gastroenterology, Wuzhong People's Hospital, Wuzhong 751100, 
      Ningxia Hui Autonomous Region, China.
FAU - Li, Xiao-Qin
AU  - Li XQ
AD  - Department of Gastroenterology, The Fifth People's Hospital of Ningxia Hui 
      Autonomous Region, Shizuishan 753000, Ningxia Hui Autonomous Region, China.
FAU - Song, Tie-Ying
AU  - Song TY
AD  - Department of Second Gastroenterology, The Sixth People's Hospital of Shenyang, 
      Shenyang 110000, Liaoning Province, China.
FAU - Qi, Hai-Long
AU  - Qi HL
AD  - Department of Gastroenterology, Shizuishan Second People's Hospital, Shizuishan 
      753000, Ningxia Hui Autonomous Region, China.
FAU - Jiao, Tai-Wei
AU  - Jiao TW
AD  - Department of Gastroenterology, The First Affiliated Hospital of China Medical 
      University, Shenyang 110000, Liaoning Province, China.
FAU - Liu, Meng-Yuan
AU  - Liu MY
AD  - Department of Gastroenterology, The First Affiliated Hospital of China Medical 
      University, Shenyang 110000, Liaoning Province, China.
FAU - He, Fang
AU  - He F
AD  - Department of Gastroenterology, Ningxia Medical University General Hospital, 
      Yinchuan 750000, Ningxia Hui Autonomous Region, China.
FAU - Zhu, Jun
AU  - Zhu J
AD  - Department of Gastroenterology, The Fifth People's Hospital of Ningxia Hui 
      Autonomous Region, Shizuishan 753000, Ningxia Hui Autonomous Region, China.
FAU - Ma, Bin
AU  - Ma B
AD  - Department of Gastroenterology, Yinchuan First People's Hospital, Yinchuan 
      750000, Ningxia Hui Autonomous Region, China.
FAU - Yu, Xiao-Bin
AU  - Yu XB
AD  - Department of Gastroenterology, People's Hospital of Ningxia Hui Autonomous 
      Region, Ningxia Medical University Affiliated People's Hospital of Autonomous 
      Region, Yinchuan 750000, Ningxia Hui Autonomous Region, China.
FAU - Guo, Jian-Yang
AU  - Guo JY
AD  - Department of Gastroenterology, People's Hospital of Ningxia Hui Autonomous 
      Region, Ningxia Medical University Affiliated People's Hospital of Autonomous 
      Region, Yinchuan 750000, Ningxia Hui Autonomous Region, China.
FAU - Yu, Yue-Hua
AU  - Yu YH
AD  - Department of Gastroenterology, Yinchuan First People's Hospital, Yinchuan 
      750000, Ningxia Hui Autonomous Region, China.
FAU - Yong, Hai-Jiang
AU  - Yong HJ
AD  - Department of Gastroenterology, Wuzhong People's Hospital, Wuzhong 751100, 
      Ningxia Hui Autonomous Region, China.
FAU - Yao, Wen-Tun
AU  - Yao WT
AD  - Department of Gastroenterology, Yinchuan First People's Hospital, Yinchuan 
      750000, Ningxia Hui Autonomous Region, China.
FAU - Ye, Ting
AU  - Ye T
AD  - Department of Gastroenterology, Yinchuan First People's Hospital, Yinchuan 
      750000, Ningxia Hui Autonomous Region, China.
FAU - Wang, Hua
AU  - Wang H
AD  - Department of Gastroenterology, The Fifth People's Hospital of Ningxia Hui 
      Autonomous Region, Shizuishan 753000, Ningxia Hui Autonomous Region, China.
FAU - Dong, Wen-Fu
AU  - Dong WF
AD  - Department of Gastroenterology, The Fifth People's Hospital of Ningxia Hui 
      Autonomous Region, Shizuishan 753000, Ningxia Hui Autonomous Region, China.
FAU - Liu, Jian-Guo
AU  - Liu JG
AD  - Department of Gastroenterology, Zhongwei People's Hospital, Zhongwei 755000, 
      Ningxia Hui Autonomous Region, China.
FAU - Wei, Qiang
AU  - Wei Q
AD  - Department of Gastroenterology, Zhongwei People's Hospital, Zhongwei 755000, 
      Ningxia Hui Autonomous Region, China.
FAU - Tian, Jing
AU  - Tian J
AD  - Department of Gastroenterology, Zhongwei People's Hospital, Zhongwei 755000, 
      Ningxia Hui Autonomous Region, China.
FAU - Li, Xiao-Guo
AU  - Li XG
AD  - Institute of Portal Hypertension, The First Hospital of Lanzhou University, 
      Lanzhou 730000, Gansu Province, China.
FAU - Dray, Xavier
AU  - Dray X
AD  - Department of Hepato-Gastroenterology, ETIS, ENSEA, CNRS, Sorbonne Universite & 
      APHP, Hopital Saint Antoine, Universite Paris-Seine, Universite de 
      Cergy-Pontoise, Paris 75012, Selectionner, France.
FAU - Qi, Xiao-Long
AU  - Qi XL
AD  - Center of Portal Hypertension, Department of Radiology, Zhongda Hospital, Medical 
      School, Southeast University, Nanjing 210000, Jiangsu Province, China. 
      qixiaolong@vip.163.com.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - World J Gastrointest Endosc
JT  - World journal of gastrointestinal endoscopy
JID - 101532474
PMC - PMC10514704
OTO - NOTNLM
OT  - Cirrhosis
OT  - Endoscopic ruler
OT  - Esophagogastroduodenoscopy
OT  - Oesophageal varices
OT  - Portal hypertension
COIS- Conflict-of-interest statement: All authors declared no conflicts of interest 
      related to this study.
EDAT- 2023/09/25 06:42
MHDA- 2023/09/25 06:43
PMCR- 2023/09/16
CRDT- 2023/09/25 04:42
PHST- 2023/08/03 00:00 [received]
PHST- 2023/08/18 00:00 [revised]
PHST- 2023/09/01 00:00 [accepted]
PHST- 2023/09/25 06:43 [medline]
PHST- 2023/09/25 06:42 [pubmed]
PHST- 2023/09/25 04:42 [entrez]
PHST- 2023/09/16 00:00 [pmc-release]
AID - 10.4253/wjge.v15.i9.564 [doi]
PST - ppublish
SO  - World J Gastrointest Endosc. 2023 Sep 16;15(9):564-573. doi: 
      10.4253/wjge.v15.i9.564.