PMID- 37744992
OWN - NLM
STAT- MEDLINE
DCOM- 20230926
LR  - 20230926
IS  - 1750-2659 (Electronic)
IS  - 1750-2640 (Print)
IS  - 1750-2640 (Linking)
VI  - 17
IP  - 9
DP  - 2023 Sep
TI  - Lessons learned from identifying clusters of severe acute respiratory infections 
      with influenza sentinel surveillance, Bangladesh, 2009-2020.
PG  - e13201
LID - 10.1111/irv.13201 [doi]
LID - e13201
AB  - BACKGROUND: We explored whether hospital-based surveillance is useful in 
      detecting severe acute respiratory infection (SARI) clusters and how often these 
      events result in outbreak investigation and community mitigation. METHODS: During 
      May 2009-December 2020, physicians at 14 sentinel hospitals prospectively 
      identified SARI clusters (i.e., >/=2 SARI cases who developed symptoms </=10 days of 
      each other and lived <30 min walk or <3 km from each other). Oropharyngeal and 
      nasopharyngeal swabs were tested for influenza and other respiratory viruses by 
      real-time reverse transcriptase-polymerase chain reaction (rRT-PCR). We describe 
      the demographic of persons within clusters, laboratory results, and outbreak 
      investigations. RESULTS: Field staff identified 464 clusters comprising 1427 SARI 
      cases (range 0-13 clusters per month). Sixty percent of clusters had three, 23% 
      had two, and 17% had >/=4 cases. Their median age was 2 years (inter-quartile range 
      [IQR] 0.4-25) and 63% were male. Laboratory results were available for the 464 
      clusters with a median of 9 days (IQR = 6-13 days) after cluster identification. 
      Less than one in five clusters had cases that tested positive for the same virus: 
      respiratory syncytial virus (RSV) in 58 (13%), influenza viruses in 24 (5%), 
      human metapneumovirus (HMPV) in five (1%), human parainfluenza virus (HPIV) in 
      three (0.6%), adenovirus in two (0.4%). While 102/464 (22%) had poultry exposure, 
      none tested positive for influenza A (H5N1) or A (H7N9). None of the 464 clusters 
      led to field deployments for outbreak response. CONCLUSIONS: For 11 years, none 
      of the hundreds of identified clusters led to an emergency response. The value of 
      this event-based surveillance might be improved by seeking larger clusters, with 
      stronger epidemiologic ties or decedents.
CI  - (c) 2023 The Authors. Influenza and Other Respiratory Viruses published by John 
      Wiley & Sons Ltd.
FAU - Islam, Md Ariful
AU  - Islam MA
AUID- ORCID: 0000-0002-0734-5832
AD  - Infectious Diseases Division, icddr,b Dhaka Bangladesh.
FAU - Hassan, Md Zakiul
AU  - Hassan MZ
AD  - Infectious Diseases Division, icddr,b Dhaka Bangladesh.
AD  - Nuffield Department of Medicine University of Oxford Oxford UK.
FAU - Aleem, Mohammad Abdul
AU  - Aleem MA
AUID- ORCID: 0000-0003-1634-8725
AD  - Infectious Diseases Division, icddr,b Dhaka Bangladesh.
AD  - School of Population Health University of New South Wales Sydney New South Wales 
      Australia.
FAU - Akhtar, Zubair
AU  - Akhtar Z
AUID- ORCID: 0000-0001-5054-9243
AD  - Infectious Diseases Division, icddr,b Dhaka Bangladesh.
AD  - Biosecurity Program, Kirby Institute University of New South Wales Sydney New 
      South Wales Australia.
FAU - Chowdhury, Sukanta
AU  - Chowdhury S
AD  - Infectious Diseases Division, icddr,b Dhaka Bangladesh.
FAU - Rahman, Mustafizur
AU  - Rahman M
AD  - Infectious Diseases Division, icddr,b Dhaka Bangladesh.
FAU - Rahman, Mohammed Ziaur
AU  - Rahman MZ
AD  - Infectious Diseases Division, icddr,b Dhaka Bangladesh.
FAU - Ahmmed, Md Kaousar
AU  - Ahmmed MK
AD  - Infectious Diseases Division, icddr,b Dhaka Bangladesh.
FAU - Mah-E-Muneer, Syeda
AU  - Mah-E-Muneer S
AD  - Infectious Diseases Division, icddr,b Dhaka Bangladesh.
FAU - Alamgir, A S M
AU  - Alamgir ASM
AD  - Institute of Epidemiology, Disease Control and Research (IEDCR) Dhaka Bangladesh.
FAU - Anwar, Shah Niaz Rubaid
AU  - Anwar SNR
AD  - Institute of Epidemiology, Disease Control and Research (IEDCR) Dhaka Bangladesh.
FAU - Alam, Ahmed Nawsher
AU  - Alam AN
AD  - Institute of Epidemiology, Disease Control and Research (IEDCR) Dhaka Bangladesh.
FAU - Shirin, Tahmina
AU  - Shirin T
AD  - Institute of Epidemiology, Disease Control and Research (IEDCR) Dhaka Bangladesh.
FAU - Rahman, Mahmudur
AU  - Rahman M
AD  - Global Health Development EMPHNET Dhaka Bangladesh.
FAU - Davis, William W
AU  - Davis WW
AUID- ORCID: 0000-0001-7062-9531
AD  - Influenza Division Centers for Disease Control and Prevention (CDC) Atlanta 
      Georgia USA.
FAU - Mott, Joshua A
AU  - Mott JA
AUID- ORCID: 0000-0001-6474-8390
AD  - Influenza Division Centers for Disease Control and Prevention (CDC) Atlanta 
      Georgia USA.
FAU - Azziz-Baumgartner, Eduardo
AU  - Azziz-Baumgartner E
AUID- ORCID: 0000-0002-0298-5814
AD  - Influenza Division Centers for Disease Control and Prevention (CDC) Atlanta 
      Georgia USA.
FAU - Chowdhury, Fahmida
AU  - Chowdhury F
AD  - Infectious Diseases Division, icddr,b Dhaka Bangladesh.
LA  - eng
GR  - U01 GH002259/GH/CGH CDC HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
DEP - 20230922
PL  - England
TA  - Influenza Other Respir Viruses
JT  - Influenza and other respiratory viruses
JID - 101304007
SB  - IM
MH  - Humans
MH  - Male
MH  - Child, Preschool
MH  - Female
MH  - *Influenza, Human/epidemiology
MH  - Bangladesh/epidemiology
MH  - *Influenza A Virus, H5N1 Subtype
MH  - *Influenza A Virus, H7N9 Subtype
MH  - Sentinel Surveillance
MH  - *Pneumonia
PMC - PMC10515138
OTO - NOTNLM
OT  - Bangladesh
OT  - SARI
OT  - cluster
OT  - influenza
OT  - surveillance
COIS- None declared.
EDAT- 2023/09/25 06:43
MHDA- 2023/09/26 13:44
PMCR- 2023/09/22
CRDT- 2023/09/25 04:52
PHST- 2022/10/31 00:00 [received]
PHST- 2023/08/29 00:00 [revised]
PHST- 2023/08/31 00:00 [accepted]
PHST- 2023/09/26 13:44 [medline]
PHST- 2023/09/25 06:43 [pubmed]
PHST- 2023/09/25 04:52 [entrez]
PHST- 2023/09/22 00:00 [pmc-release]
AID - IRV13201 [pii]
AID - 10.1111/irv.13201 [doi]
PST - epublish
SO  - Influenza Other Respir Viruses. 2023 Sep 22;17(9):e13201. doi: 10.1111/irv.13201. 
      eCollection 2023 Sep.