PMID- 37746146 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230926 IS - 1662-4548 (Print) IS - 1662-453X (Electronic) IS - 1662-453X (Linking) VI - 17 DP - 2023 TI - The durable effect of acupuncture for episodic migraine: a systematic review and meta-analysis. PG - 1211438 LID - 10.3389/fnins.2023.1211438 [doi] LID - 1211438 AB - BACKGROUND: Migraine is a common and recurrent type of headache. Avoiding trigger factors is not often successful in reducing headache frequency, duration, and severity. Prophylactic medications may be effective but are limited by strict indications and daily medication intake. This review aimed to investigate the durable effect of acupuncture on episodic migraine. METHODS: Seven databases including Medline, Embase, PubMed, etc., were searched for English and Chinese literature from their inception to 23 November 2022. Two independent reviewers screened the retrieved studies and extracted the data. Primary outcomes were monthly migraine days, monthly migraine attacks, and VAS score at 3 months post-treatment. The risk of bias in included studies was assessed using the Cochrane Risk of Bias 2.0 tool. Meta-analysis was conducted where applicable. RESULTS: Fifteen studies were included in this review. Acupuncture reduced the number of migraine attacks (MD -0.68; 95% CI -0.93, -0.43; p < 0.001), the number of days with migraine (MD -0.86; 95% CI -1.18, -0.55; p < 0.001), and VAS score (MD -1.01; 95% CI -1.30, -0.72; p < 0.001) to a greater degree than sham acupuncture at 3 months after treatment. Significant differences in reducing pain intensity of migraine in favor of acupuncture compared with waitlist (MD -1.84; 95% CI -2.31, -1.37; p < 0.001) or flunarizine (MD -2.00; 95% CI -2.35, -1.65; p < 0.001) at 3 months after treatment were found, and the differences reached the minimal clinically important difference (MCID). CONCLUSION: This review found that the durable effect of acupuncture for episodic migraine lasted at least 3 months after treatment. More high-quality studies with longer follow-up periods in the future are needed to confirm the findings. CI - Copyright (c) 2023 Shi, Miao, Gao, Zhu, Fang and Liu. FAU - Shi, Hangyu AU - Shi H AD - Department of Acupuncture, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. AD - Graduate College, Beijing University of Chinese Medicine, Beijing, China. FAU - Miao, Runyu AU - Miao R AD - Graduate College, Beijing University of Chinese Medicine, Beijing, China. AD - Institute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. FAU - Gao, Shuai AU - Gao S AD - Department of Acupuncture, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. FAU - Zhu, Lili AU - Zhu L AD - Department of Acupuncture, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. FAU - Fang, Jiufei AU - Fang J AD - Department of Acupuncture, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. FAU - Liu, Zhishun AU - Liu Z AD - Department of Acupuncture, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. LA - eng PT - Systematic Review DEP - 20230908 PL - Switzerland TA - Front Neurosci JT - Frontiers in neuroscience JID - 101478481 PMC - PMC10514352 OTO - NOTNLM OT - RCTs OT - acupuncture OT - durable effect OT - migraine OT - systematic review COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2023/09/25 06:42 MHDA- 2023/09/25 06:43 PMCR- 2023/01/01 CRDT- 2023/09/25 05:12 PHST- 2023/04/24 00:00 [received] PHST- 2023/08/21 00:00 [accepted] PHST- 2023/09/25 06:43 [medline] PHST- 2023/09/25 06:42 [pubmed] PHST- 2023/09/25 05:12 [entrez] PHST- 2023/01/01 00:00 [pmc-release] AID - 10.3389/fnins.2023.1211438 [doi] PST - epublish SO - Front Neurosci. 2023 Sep 8;17:1211438. doi: 10.3389/fnins.2023.1211438. eCollection 2023.