PMID- 37748503
OWN - NLM
STAT- MEDLINE
DCOM- 20240205
LR  - 20240206
IS  - 1438-8782 (Electronic)
IS  - 0172-4614 (Linking)
VI  - 45
IP  - 1
DP  - 2024 Feb
TI  - EFSUMB Technical Review - Update 2023: Dynamic Contrast-Enhanced Ultrasound 
      (DCE-CEUS) for the Quantification of Tumor Perfusion.
PG  - 36-46
LID - 10.1055/a-2157-2587 [doi]
AB  - Dynamic contrast-enhanced ultrasound (DCE-US) is a technique to quantify tissue 
      perfusion based on phase-specific enhancement after the injection of microbubble 
      contrast agents for diagnostic ultrasound. The guidelines of the European 
      Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) published 
      in 2004 and updated in 2008, 2011, and 2020 focused on the use of 
      contrast-enhanced ultrasound (CEUS), including essential technical requirements, 
      training, investigational procedures and steps, guidance regarding image 
      interpretation, established and recommended clinical indications, and safety 
      considerations. However, the quantification of phase-specific enhancement 
      patterns acquired with ultrasound contrast agents (UCAs) is not discussed here. 
      The purpose of this EFSUMB Technical Review is to further establish a basis for 
      the standardization of DCE-US focusing on treatment monitoring in oncology. It 
      provides some recommendations and descriptions as to how to quantify dynamic 
      ultrasound contrast enhancement, and technical explanations for the analysis of 
      time-intensity curves (TICs). This update of the 2012 EFSUMB introduction to 
      DCE-US includes clinical aspects for data collection, analysis, and 
      interpretation that have emerged from recent studies. The current study not only 
      aims to support future work in this research field but also to facilitate a 
      transition to clinical routine use of DCE-US.
CI  - Thieme. All rights reserved.
FAU - Dietrich, Christoph F
AU  - Dietrich CF
AUID- ORCID: 0000-0001-6015-6347
AD  - Department General Internal Medicine, Kliniken Hirslanden Beau Site, Salem und 
      Permanence, Bern, Switzerland.
AD  - Zentrum der Inneren Medizin, Johann Wolfgang Goethe Universitatsklinik Frankfurt, 
      Frankfurt, Germany.
FAU - Correas, Jean-Michel
AU  - Correas JM
AD  - Department of Adult Radiology, Assistance Publique Hopitaux de Paris, Necker 
      University Hospital, Paris, France.
AD  - Paris Cite University, Paris, France.
AD  - CNRS, INSERM Laboratoire d'Imagerie Biomedicale, Sorbonne Universite, Paris, 
      France.
FAU - Cui, Xin-Wu
AU  - Cui XW
AUID- ORCID: 0000-0003-3890-6660
AD  - Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, 
      Huazhong University of Science and Technology, Wuhan, China.
FAU - Dong, Yi
AU  - Dong Y
AD  - Department of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiaotong 
      University School of Medicine, Shanghai, China.
FAU - Havre, Roald Flesland
AU  - Havre RF
AUID- ORCID: 0000-0003-3004-551X
AD  - Department of Medicine, National Centre for Ultrasound in Gastroenterology, 
      Haukeland University Hospital, Bergen, Norway.
AD  - Department of Clinical Medicine, University of Bergen, Bergen, Norway.
FAU - Jenssen, Christian
AU  - Jenssen C
AUID- ORCID: 0000-0002-9530-1919
AD  - Department of Internal Medicine, Krankenhaus Markisch Oderland Strausberg/ 
      Wriezen, Wriezen, Germany.
AD  - Brandenburg Institute for Clinical Ultrasound (BICUS), Medical University 
      Brandenburg, Neuruppin, Brandenburg, Germany.
FAU - Jung, Ernst Michael
AU  - Jung EM
AD  - Institute of Diagnostic Radiology, Interdisciplinary Ultrasound Department, 
      University Hospital Regensburg, Regensburg, Germany.
FAU - Krix, Martin
AU  - Krix M
AD  - Global Medical & Regulatory Affairs, Bracco Imaging, Konstanz, Germany.
FAU - Lim, Adrian
AU  - Lim A
AUID- ORCID: 0000-0003-3904-2876
AD  - Department of Imaging, Imperial College London and Healthcare NHS Trust, Charing 
      Cross Hospital Campus, London, United Kingdom of Great Britain and Northern 
      Ireland.
FAU - Lassau, Nathalie
AU  - Lassau N
AD  - Imaging Department. Gustave Roussy cancer Campus. Villejuif, France. BIOMAPS. UMR 
      1281. CEA. CNRS. INSERM, Universite Paris-Saclay, France.
FAU - Piscaglia, Fabio
AU  - Piscaglia F
AUID- ORCID: 0000-0001-8264-1845
AD  - Division of Internal Medicine, Hepatobiliary and Immunoallergic Diseases, IRCCS 
      Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
AD  - Dept of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
LA  - eng
PT  - Journal Article
TT  - Technisches Review der EFSUMB - Update 2023: Dynamischer kontrastverstarkter 
      Ultraschall (DCE-US) zur Quantifizierung der Tumorperfusion.
DEP - 20230925
PL  - Germany
TA  - Ultraschall Med
JT  - Ultraschall in der Medizin (Stuttgart, Germany : 1980)
JID - 8303585
RN  - 0 (Contrast Media)
SB  - IM
MH  - Humans
MH  - *Contrast Media
MH  - Ultrasonography/methods
MH  - *Neoplasms
MH  - Perfusion
COIS- All other authors have received lecture honoraria from Bracco and from companies 
      selling ultrasound systems. Martin Krix is employee of Bracco.
EDAT- 2023/09/26 00:42
MHDA- 2024/02/05 06:42
CRDT- 2023/09/25 18:53
PHST- 2024/02/05 06:42 [medline]
PHST- 2023/09/26 00:42 [pubmed]
PHST- 2023/09/25 18:53 [entrez]
AID - 10.1055/a-2157-2587 [doi]
PST - ppublish
SO  - Ultraschall Med. 2024 Feb;45(1):36-46. doi: 10.1055/a-2157-2587. Epub 2023 Sep 
      25.